Charles D Derby

US Patent:

20060051337, Mar 9, 2006

Filed:

Apr 6, 2005

Appl. No.:

11/100328

Inventors:

Paul Johnson - Brighton MI, US
Hsiuchin Yang - Decatur GA, US
Charles Derby - Atlanta GA, US
Phang Tai - Atlanta GA, US

International Classification:

A61K 38/44
C12N 9/02
C07H 21/04
C12P 21/06

US Classification:

424094400, 435069100, 435189000, 435320100, 435325000, 536023200

Abstract:

The present invention provides an isolated polypeptide (escapin), and fragments thereof, from the sea hare that have antimicrobial action directed against fungi, yeast, bacteria, and cyanobacteria. Further, the present invention provides an isolated nucleic acid, and fragments thereof, that encode the polypeptide and fragments thereof. Also provided are primers for detecting the nucleic acids of the present invention. A method of inhibiting microbial growth and inhibiting biofilm formation on a surface is also provided.

US Patent:

20110165261, Jul 7, 2011

Filed:

Jul 27, 2009

Appl. No.:

13/055221

Inventors:

Charles Derby - Decatur GA, US
Binghe Wang - Marietta GA, US
Phang C. Tai - Atlanta GA, US
Ko-Chun Ko - Taichung, TW
Michiya Kamio - Tokyo, JP

Assignee:

GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC - ATLANTA GA

International Classification:

A61K 33/40
A01N 59/00
A61K 31/19
A01N 37/00
A01P 1/00
A61P 31/00

US Classification:

424616, 514557

Abstract:

Disclosed herein are antimicrobial compositions, kits, and articles of manufacture. Further disclosed herein are methods for treating surfaces, including tissue, inter alia, wounds, with the disclosed compositions.