Cheryl Lynne Armstrong

US Patent:

20020137762, Sep 26, 2002

Filed:

Jan 25, 2002

Appl. No.:

10/056913

Inventors:

Harish Joshi - Decatur GA, US
Keqiang Ye - Lilburn GA, US
Judith Kapp - Atlanta GA, US
Jaren Landen - Decatur GA, US
David Archer - Roswell GA, US
Cheryl Armstrong - Winnetka IL, US
Fuqiang Liu - Edison NJ, US

International Classification:

A61K031/4741
A61K031/36

US Classification:

514/291000, 514/466000

Abstract:

The present invention relates to methods useful for the treatment of neoplastic diseases, tumor cells, and the treatment of cancer delivering compounds of the formula The invention provides various methods of delivering such compounds, combinations of treatments, and altering such compounds to enhance their effectiveness.

US Patent:

20020012630, Jan 31, 2002

Filed:

May 9, 2001

Appl. No.:

09/851743

Inventors:

James Nolan - Guilford CT, US
Cheryl Armstrong - Atlanta GA, US
John Ansel - Atlanta GA, US

International Classification:

A61K049/00

US Classification:

424/009200

Abstract:

The present invention provides methods for testing compounds to determine whether such compounds are useful for improving treatment of wounds in animals, particularly diabetic animals, and improving diabetic neuropathy or neurological disorders associated with diabetes. The invention also provides methods for characterizing compounds, particularly aldose reductase inhibitors, that are useful in improving wound healing in diabetic animals or improving diabetic neuropathy or neurological disorders associated with diabetes. In addition, the invention relates to methods for improving wound healing and improves diabetic neuropathy or neurological disorders associated with diabetes in diabetic animals using aldose reductase inhibitors.