Christian Munz

US Patent:

20100266541, Oct 21, 2010

Filed:

Feb 20, 2007

Appl. No.:

12/280269

Inventors:

Christian Munz - New York NY, US

International Classification:

A61K 38/21
A61K 39/00
A61K 39/12
A61K 39/04
A61K 39/02
A61K 35/12
C12N 5/10
C12N 5/02
C12N 15/00
C07H 21/04
A61P 37/00

US Classification:

424 855, 4241841, 4242041, 4242341, 4242481, 424 9371, 435325, 435375, 4353201, 536 231, 536 2372

Abstract:

This invention is directed to the targeting of proteins or peptides of interest to an autophagosome, for their presentation on a major histocompatibility complex (MHC) class II molecule and methods of use thereof. Nucleic acids, vectors comprising the same, and compositions for targeting proteins or peptides of interest to an autophagosome, for their presentation on a major histocompatibility complex (MHC) class II molecule are disclosed as are methods of use thereof for stimulating or enhancing immune responses in a subject.

US Patent:

20090155208, Jun 18, 2009

Filed:

Feb 20, 2007

Appl. No.:

11/708125

Inventors:

Christian Munz - New York NY, US

International Classification:

A61K 38/21
C07H 21/00
C12N 15/63
C12N 5/00
C12N 5/02
A61K 31/7052
A61K 35/12
A61P 37/02

US Classification:

424 855, 536 234, 4353201, 435325, 435375, 514 44, 424 937, 424 9371

Abstract:

This invention is directed to the targeting of proteins or peptides of interest to an autophagosome, for their presentation on a major histocompatibility complex (MHC) class II molecule and methods of use thereof. Nucleic acids, vectors comprising the same, and compositions for targeting proteins or peptides of interest to an autophagosome, for their presentation on a major histocompatibility complex (MHC) class II molecule are disclosed as are methods of use thereof for stimulating or enhancing immune responses in a subject.