Christopher D Austin

US Patent:

20130123214, May 16, 2013

Filed:

Jul 19, 2011

Appl. No.:

13/810774

Inventors:

Wei Zheng - Potomac MD, US
Juan Jose Marugan - Gaithersburg MD, US
Ke Liu - Cambridge MD, US
Noel Terrence Southall - Chevy Chase MD, US
Christopher P. Austin - Potomac MD, US

Assignee:

The United States of America as Represented by the Secretary Department of HR - Rockville MD

International Classification:

A61K 31/355
A61K 31/724
A61K 45/06

US Classification:

514 58, 514458

Abstract:

This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of delta tocopherol in the treatment of diseases and conditions related to lysosomal storage disorders. Included in the present disclosure is a method for the modulation of cholesterol recycling. Further, the disclosure relates to conditions such as Niemann-Pick type C disease, Farber disease, Niemann-Pick type A disease, Wolman disease and Tay Sachs disease. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of delta tocopherol. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of delta tocopherol in combination with cyclodextrin to a patient in need thereof.

US Patent:

20210039901, Feb 11, 2021

Filed:

Oct 21, 2020

Appl. No.:

17/076701

Inventors:

- Washington DC, US
Edward F. Houston - Bristow VA, US
Juan A. Roman - Fairfax VA, US
Leung M. Shiu - Gaithersburg MD, US
Riley H. Mayhall - Germantown MD, US
Jacob L. Timm - Pasadena MD, US
Matthew G. Good - Eldersburg MD, US
William P. McConnell - Woodstock MD, US
Robert L. Schlender - Columbia MD, US
Christopher D. Austin - Parkville MD, US

International Classification:

B65H 3/12
B65H 5/24
B65H 3/46
B65H 5/22
B65H 7/12
B65G 47/06
B65G 47/28
B65G 47/46
B65G 59/04

Abstract:

Embodiments of a system and method for shingulating, singulating, and synchronizing articles in an article feeder system are disclosed. The article feeder system may include a shingulating device configured to receive a stack of articles and to produce a positively lapped stack of articles, a plurality of picking devices configured to pick one or more articles from the positively lapped stack of articles and to produce one or more singulated articles, and one or more synchronization devices configured to deliver the one or more singulated articles to one or more sorter windows.

US Patent:

20190367293, Dec 5, 2019

Filed:

Aug 15, 2019

Appl. No.:

16/542172

Inventors:

- Washington DC, US
Edward F. Houston - Bristow VA, US
Juan A. Roman - Fairfax VA, US
Leung M. Shiu - Gaithersburg MD, US
Riley H. Mayhall - Germantown MD, US
Jacob L. Timm - Pasadena MD, US
Matthew G. Good - Eldersburg MD, US
William P. McConnell - Woodstock MD, US
Robert L. Schlender - Columbia MD, US
Christopher D. Austin - Parkville MD, US

International Classification:

B65G 47/74
B65H 5/24
B65H 3/46
B65H 5/22
B65H 7/12
B65H 3/12
B65G 47/06
B65G 47/28
B65G 47/46
B65G 59/04

Abstract:

Embodiments of a system and method for shingulating, singulating, and synchronizing articles in an article feeder system are disclosed. The article feeder system may include a shingulating device configured to receive a stack of articles and to produce a positively lapped stack of articles, a plurality of picking devices configured to pick one or more articles from the positively lapped stack of articles and to produce one or more singulated articles, and one or more synchronization devices configured to deliver the one or more singulated articles to one or more sorter windows.

US Patent:

20180265308, Sep 20, 2018

Filed:

May 24, 2018

Appl. No.:

15/989039

Inventors:

- Washington DC, US
Edward F. Houston - Bristow VA, US
Juan A. Roman - Fairfax VA, US
Leung M. Shiu - Gaithersburg MD, US
Riley H. Mayhall - Germantown MD, US
Jacob L. Timm - Pasadena MD, US
Matthew G. Good - Eldersburg MD, US
William P. McConnell - Woodstock MD, US
Robert L. Schlender - Columbia MD, US
Christopher D. Austin - Parkville MD, US

International Classification:

B65G 47/74
B65H 5/24
B65H 5/22
B65G 59/04
B65G 47/46
B65G 47/28
B65G 47/06
B65H 3/12
B65H 3/46

Abstract:

Embodiments of a system and method for shingulating, singulating, and synchronizing articles in an article feeder system are disclosed. The article feeder system may include a shingulating device configured to receive a stack of articles and to produce a positively lapped stack of articles, a plurality of picking devices configured to pick one or more articles from the positively lapped stack of articles and to produce one or more singulated articles, and one or more synchronization devices configured to deliver the one or more singulated articles to one or more sorter windows.

US Patent:

20170027903, Feb 2, 2017

Filed:

Aug 17, 2016

Appl. No.:

15/239753

Inventors:

- Rockville MD, US
Juan Jose Marugan - Gaithersburg MD, US
Ke Liu - Cambridge MD, US
Noel Terrence Southall - Chevy Chase MD, US
Christopher P. Austin - Potomac MD, US

International Classification:

A61K 31/355
A61K 31/36
A61K 36/185
A61K 31/496
A61K 31/724
A61K 45/06

Abstract:

This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of δ tocopherol in the treatment of diseases and conditions related to lysosomal storage disorders. Included in the present disclosure is a method for the modulation of cholesterol recycling. Further, the disclosure relates to conditions such as Niemann-Pick type C disease, Farber disease, Niemann-Pick type A disease, Wolman disease and Tay Sachs disease. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of δ tocopherol. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of δ tocopherol in combination with cyclodextrin to a patient in need thereof.

US Patent:

20160001985, Jan 7, 2016

Filed:

Jun 17, 2015

Appl. No.:

14/742480

Inventors:

- Washington DC, US
Edward F. Houston - Bristow VA, US
Juan A. Roman - Fairfax VA, US
Leung M. Shiu - Gaithersburg MD, US
Riley H. Mayhall - Germantown MD, US
Jacob L. Timm - Pasadena MD, US
Matthew G. Good - Eldersburg MD, US
William P. McConnell - Woodstock MD, US
Robert L. Schlender - Columbia MD, US
Christopher D. Austin - Parkville MD, US

International Classification:

B65G 47/74
B65G 59/04
B65G 47/46
B65G 47/06
B65G 47/28

Abstract:

Embodiments of a system and method for shingulating, singulating, and synchronizing articles in an article feeder system are disclosed. The article feeder system may include a shingulating device configured to receive a stack of articles and to produce a positively lapped stack of articles, a plurality of picking devices configured to pick one or more articles from the positively lapped stack of articles and to produce one or more singulated articles, and one or more synchronization devices configured to deliver the one or more singulated articles to one or more sorter windows.

US Patent:

20150265571, Sep 24, 2015

Filed:

May 13, 2015

Appl. No.:

14/711381

Inventors:

- ROCKVILLE MD, US
Juan Jose MARUGAN - GAITHERSBURG MD, US
Ke LIU - CAMBRIDGE MD, US
Noel Terrence SOUTHALL - CHEVY CHASE MD, US
Christopher P. AUSTIN - POTOMAC MD, US

International Classification:

A61K 31/355

Abstract:

This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of δ tocopherol in the treatment of diseases and conditions related to lysosomal storage disorders. Included in the present disclosure is a method for the modulation of cholesterol recycling. Further, the disclosure relates to conditions such as Niemann-Pick type C disease, Farber disease, Niemann-Pick type A disease, Wolman disease and Tay Sachs disease. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of δ tocopherol. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of δ tocopherol in combination with cyclodextrin to a patient in need thereof.

US Patent:

20140271090, Sep 18, 2014

Filed:

Mar 14, 2013

Appl. No.:

13/827122

Inventors:

United States Postal Service - , US
Edward F. Houston - Bristow VA, US
Juan A. Roman - Fairfax VA, US
Leung M. Shiu - Gaithersburg MD, US
Riley H. Mayhall - Germantown MD, US
Jacob L. Timm - Pasadena MD, US
Matthew G. Good - Eldersburg MD, US
William P. McConnell - Woodstock MD, US
Robert L. Schlender - Columbia MD, US
Christopher D. Austin - Parkville MD, US

International Classification:

B65G 47/91

US Classification:

414797, 4147972, 414801

Abstract:

Embodiments of a system and method for shingulating, singulating, and synchronizing articles in an article feeder system are disclosed. The article feeder system may include a shingulating device configured to receive a stack of articles and to produce a positively lapped stack of articles, a plurality of picking devices configured to pick one or more articles from the positively lapped stack of articles and to produce one or more singulated articles, and one or more synchronization devices configured to deliver the one or more singulated articles to one or more sorter windows.