Christopher M Bailey

US Patent:

8352215, Jan 8, 2013

Filed:

Oct 23, 2009

Appl. No.:

12/604631

Inventors:

Lin (Colin) Chen - Rockville MD, US
Steve Krueger - Raleigh NC, US
Christopher D. Bailey - Cary NC, US

Assignee:

SAS Institute Inc. - Cary NC

International Classification:

G06F 17/18
G06F 19/00

US Classification:

702179

Abstract:

Systems and methods are provided for performing an estimation using an iteratively reweighted least squares technique on a scenario defined by a design matrix, a response variable vector, and a parameter to be estimated. A system and method can be configured to include a root data processor, where a least squares estimate is calculated by the root data processor during each of a plurality of processing iterations. A plurality of node data processors can also be configured to: update values of a weight matrix according to a current state of the least squares estimate, determine a first intermediate value based on the design matrix and the weight matrix, determine a second intermediate value based on the design and weight matrices and the response variable vector. The root data processor calculates an updated least squares estimate based on the intermediate values.

US Patent:

20180344642, Dec 6, 2018

Filed:

Nov 9, 2016

Appl. No.:

15/774217

Inventors:

- Washington DC, US
Yin WANG - Washington DC, US
Yan LIU - Washington DC, US
Christopher BAILEY - Merritt Island FL, US
Pan ZHENG - Washington DC, US

International Classification:

A61K 9/127
A61K 38/16
A61K 47/69
A61P 35/02
A61P 37/02

Abstract:

A liposomal drug formulation for treating a disease in a patient characterized by overexpression of HIF-1α and/or HIF-2α includes a plurality of liposomes in a pharmaceutically acceptable carrier. The liposomes encapsulate echinomycin and are made from a peglyated phospholipid, a neutral phosphoglyceride, and a sterol. The PEGylated liposomes may be used to treat proliferative diseases, leukemia, cancer, autoimmune diseases and graft-versus-host disease.

US Patent:

20140252312, Sep 11, 2014

Filed:

Mar 6, 2014

Appl. No.:

14/198735

Inventors:

Matthew Lumb - Alexandria VA, US
Michael K. Yakes - Alexandria VA, US
Marla González - Washington DC, US
Christopher Bailey - Washington DC, US
Robert J. Walters - Alexandria VA, US

Assignee:

The Government of the United States of America, as represented by the Secretary of the Navy - Washington DC

International Classification:

H01L 29/15

US Classification:

257 14

Abstract:

A strain-balanced quantum well tunnel junction (SB-QWTJ) device. QW structures are formed from alternating quantum well and barrier layers situated between n and p layers in a tunnel junction formed on a substrate. The quantum well layers exhibit a compressive strain with respect to the substrate, while the barrier layers exhibit a tensile strain. The composition and layer thicknesses of the quantum well and barrier layers are configured so that the compressive and tensile strains in the structure are balanced.