Christopher Becker - Wilmington DE, US Bruce Dembofsky - Wilmington DE, US Robert Jacobs - Wilmington DE, US James Kang - Wilmington DE, US Cyrus Ohnmacht - Wilmington DE, US James Rosamond - Wilmington DE, US Ashokkumar Bhikkappa Shenvi - Wilmington DE, US Thomas Simpson - Wilmington DE, US James Woods - Wilmington DE, US
Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid β protein production and neurological disorders such as Alzheimer's disease. These compounds inhibit γ secretase and thereby inhibit the production of amyloid β protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.
Marc J. Chapdelaine - Wilmington DE, US Cyrus J. Ohnmacht - Wilmington DE, US Christopher Becker - West Chester PA, US Hui-Fang Chang - Wilmington DE, US Bruce T. Dembofsky - Wallingford PA, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A61K 31/502 A61K 31/498 C07D 237/28 A61P 25/22
US Classification:
514248, 544235
Abstract:
This invention relates to novel compounds having the structural formula I below:.
Marc J. Chapdelaine - Wilmington DE, US Cyrus J. Ohnmacht - Wilmington DE, US Christopher Becker - West Chester PA, US Hui-Fang Chang - Wilmington DE, US Bruce T. Dembofsky - Wallingford PA, US
Christopher Becker - Wilmington DE, US Jeanne Comstock - West Boylston MA, US William Michne - Wilmington DE, US Megan Murphy - Wilmington DE, US Eifion Phillips - Wilmington DE, US James Rosamond - Wilmington DE, US Thomas Simpson - Wilmington DE, US
International Classification:
A61K 31/4743 A61K 31/4741 A61K 31/473
US Classification:
514290000, 514291000
Abstract:
Compounds of Formula I or Formula II wherein R, X and Ar are as described in the specification, pharmaceutically-acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially for treatment of conditions associated with reductions in nicotinic transmission.
Christopher Becker - Wilmington DE, US Bruce Dembofsky - Wilmington DE, US Robert Jacobs - Wilmington DE, US James Kang - Wilmington DE, US Cyrus Ohnmacht - Wilmington DE, US James Rosamond - Wilmington DE, US Ashokkumar Shenvi - Wilmington DE, US Thomas Simpson - Wilmington DE, US James Woods - Wilmington DE, US
Assignee:
ASTRAZENECA AB - Sodertalje
International Classification:
A61K 31/554 A61P 25/28
US Classification:
514211070, 514211030
Abstract:
Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid β protein production and neurological disorders such as Alzheimer's disease. These compounds inhibit γ secretase and thereby inhibit the production of amyloid β protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.
Marc J. Chapdelaine - Wilmington DE, US Cyrus J. Ohnmacht - Wilmington DE, US Christopher Becker - West Chester PA, US Hui-Fang Chang - Wilmington DE, US Bruce T. Dembofsky - Wallingford PA, US
This invention relates to novel compounds having the structural formula I below:and their pharmaceutically acceptable salts, tautomers or in vivo-hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of anxiety disorders, cognitive disorders, and/or mood disorders.
Marc J. Chapdelaine - Wilmington DE, US Cyrus J. Ohnmacht - Wilmington DE, US Christopher Becker - West Chester PA, US Hui-Fang Chang - Wilmington DE, US Bruce T. Dembofsky - Wallingford PA, US
This invention relates to novel compounds having the structural formula I below:and their pharmaceutically acceptable salts, tautomers or in vivo-hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of anxiety disorders, cognitive disorders, and/or mood disorders.
Cinnoline Compounds For The Treatment Of Anxiety, Cognitive And Mood Disorders
Marc J. Chapdelaine - Wilmington DE, US Cyrus J. Ohnmacht - Wilmington DE, US Christopher Becker - Wilmington DE, US Hui-Fang Chang - Wilmington DE, US Bruce T. Dembofsky - Wilmington DE, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
C07D 403/10 C07D 237/28 C07D 401/10
US Classification:
544235
Abstract:
This invention relates to novel compounds having the structural formula I below:and their pharmaceutically acceptable salts, tautomers or in vivo-hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of anxiety disorders, cognitive disorders, and/or mood disorders.
Isbn (Books And Publications)
Improved Analysis of DNA Short Tandem Repeats: With Time-Of-Flight Mass Spectroscopy
817 Stratford Ave, South Pasadena, CA 91030 1250 Hoover St, Carlsbad, CA 92008
Christopher Becker Managing Director, Vice-President
Education Advisors, Inc Business Consulting Services
144 Quincy Ave, Long Beach, CA 90803
Christopher W Becker
BECK TECH LIMITED LIABILITY COMPANY
Christopher Becker Vice-President
Educational Advisors Education Management · Radio Broadcast Station
111 W Ocean Blvd SUITE 1940, Long Beach, CA 90802 555 E Ocean Blvd STE 450, Long Beach, CA 90802 211 E Ocean Blvd, Long Beach, CA 90802 5624363900
Christopher James Becker President
B SCHOOL, INC Amusement/Recreation Services
5738 E Lucia Walk, Long Beach, CA 90803 5 Arrivo Dr, San Juan Capistrano, CA 92692 3930 Paige St, Los Angeles, CA 90031 25 Catamaran St, Venice, CA 90292 6267947066
Christopher Clayton Becker President
RAIL-TECH CONSULTANTS, INC Business Consulting Services
4 Douglass Dr, Trabuco Canyon, CA 92679 37 Santa Agatha, Trabuco Canyon, CA 92688
Medical School Ohio State University College of Medicine Graduated: 1996
Procedures:
Destruction of Benign/Premalignant Skin Lesions Electrocardiogram (EKG or ECG) Hearing Evaluation Psychological and Neuropsychological Tests Pulmonary Function Tests Vaccine Administration
Dr. Becker graduated from the Ohio State University College of Medicine in 1996. He works in Rockwall, TX and specializes in Pediatrics. Dr. Becker is affiliated with Childrens Health.
West Sound Emergency Physicians 2520 Cherry Ave, Bremerton, WA 98310 3607446710 (phone), 3607446889 (fax)
Education:
Medical School University of Washington SOM Graduated: 2003
Languages:
English
Description:
Dr. Becker graduated from the University of Washington SOM in 2003. He works in Bremerton, WA and specializes in Emergency Medicine. Dr. Becker is affiliated with Harrison Medical Center and Harrison Medical Center.
Dec 2010 to 2000 Patient Appeals CoordinatorOrange Coast College
Apr 2009 to 2000 Campus Safety (CSA) / Compliance OfficerBlockbuster Newport Beach, CA Mar 2008 to May 2010 Shift ManagerMBC SYSTEMS Santa Ana, CA Mar 2007 to Apr 2007 Collections RepresentativeAPRIA HEALTHCARE Tustin, CA Nov 2006 to Mar 2007 Collections RepresentativeMPC NETWORK Costa Mesa, CA Nov 2005 to Nov 2006 Administrative Data Entry / Supply orderscategorization Newport Beach, CA Jun 2002 to Dec 2005 Supply manager
Education:
ORANGE COAST COLLEGE Jun 2004 to Jul 2006 AA in General Education
Personal Injury Plaintiffs Personal Injury No Fault Automobile Insurance Business Litigation Breach of Contract Premises Liability Hit and Run Animal Attacks Motor Vehicle Accidents
Weber State University - Sociology, University of North Carolina at Chapel Hill - Sociology
Bragging Rights:
2nd Place in Game Crazy's Halo: Reach tournament. That counts for something, right?
Christopher Becker
Work:
US Cellular - Sales
Education:
College of Lake County
Relationship:
In_a_relationship
Christopher Becker
Work:
Open Source Solutions, LLC - Consultant (2009)
About:
I am a dynamic figure, often seen scaling walls, saving money, and crushing ice. I have been known to redesign power stations on my coffee breaks, making them more efficient in the area of heat transf...
Christopher Becker
Work:
Empresa Júnior de Estatística - Diretor Financeiro (2012)
Denver, COI am currently Manager of Talent and Organizational Development for Level 3 Communications. I am managing three training development and delivery specialists... I am currently Manager of Talent and Organizational Development for Level 3 Communications. I am managing three training development and delivery specialists who manage a large workload from managing our LMS Content to Training Consultation to Training Development and Delivery. In close to 10...