Christopher Y Bull

US Patent:

53169492, May 31, 1994

Filed:

Dec 10, 1992

Appl. No.:

7/988511

Inventors:

Christopher Bull - Bethesda MD
Charles R. Barmore - Moore SC

Assignee:

W. R. Grace & Co.-Conn. - New York NY

International Classification:

G01N 3100

US Classification:

436 5

Abstract:

A method of detecting the permeability of an article to oxygen is disclosed. A fluorescent redox indicator, preferably riboflavin, is dispersed in a carrier and placed on an impermeable substrate. The article to be measured is placed adjacent to the carrier. Residual oxygen is removed, the redox indicator is photoreduced, the article and carrier are exposed to oxygen, and the indicator is exposed to UV light.

US Patent:

55830471, Dec 10, 1996

Filed:

Apr 22, 1994

Appl. No.:

8/231411

Inventors:

Thomas A. Blinka - Columbia MD
Christopher Bull - Bethesda MD
Charles R. Barmore - Moore SC
Drew V. Speer - Columbia MD

Assignee:

W. R. Grace & Co.-Conn. - New York NY

International Classification:

G01N 3100

US Classification:

436 5

Abstract:

A method of detecting the permeability of an article to oxygen is disclosed. A fluorescent redox indicator, preferably riboflavin, is dispersed in a carrier and placed on an impermeable substrate. The article to be measured is placed adjacent to the carrier. Residual oxygen is removed, the redox indicator is photoreduced, the article and carrier are exposed to oxygen, and the indicator is exposed to UV light.

US Patent:

51027925, Apr 7, 1992

Filed:

Aug 13, 1987

Appl. No.:

7/084782

Inventors:

James F. Walter - Ashton MD
Christopher Bull - Bethesda MD

Assignee:

W. R. Grace & Co.-Conn. - New York NY

International Classification:

C12P 1306

US Classification:

435116

Abstract:

L-Serine derivatives produced by the enzyme catalyzed aldol condensation of glycine and an aldehyde in aqueous solution are recovered in high yield by extracting the aqueous product solution containing said serine derivatives with an organic phase comprising (i) an aldehyde, or (ii) mixtures of an aldehyde and a water immiscible organic solvent, followed by re-extracting the organic phase with an aqueous phase having a pH of less than about 7. The L-erythro isomers of L-serine derivatives such as L-phenylserine may be preferentially prepared by the use of this extraction/re-extraction procedure in combination with bioreactor reaction conditions which include a pH of from about 7. 5 to 10, an aldehyde concentration of from about 1 to about 90 grams/liter, a glycine concentration of from about 10 to about 300 grams/liter, and a molar ratio of glycine to aldehyde of from about 4:1 to about 100:1.

US Patent:

50981862, Mar 24, 1992

Filed:

Oct 12, 1990

Appl. No.:

7/596711

Inventors:

Christopher Bull - Bethesda MD

International Classification:

G01N 2105

US Classification:

356246

Abstract:

An improvement in rapid mixers for stopped flow spectrophotometers is disclosed. This improvement involves the dispersion of one solution from the bore of a disperser through notches into a flowing sheath of a second solution. The dispersed mixture is then mixed by passage through a mixer made up of a series of mixing rings with lands and grooves. The lands and grooves of adjoining rings are aligned so grooves are adjacent to lands, thus providing maximum mixing. The ratio of volumes of solutions mixed may vary from 1:1 to 40:1 by varying the number and size of notches in the end of the disperser tube. The viscosity ratio of the solutions mixed may vary from 1:1 to 100:1. Complete (greater than 99%) mixing occurs in less than one millisecond.

US Patent:

20190010076, Jan 10, 2019

Filed:

Jun 29, 2018

Appl. No.:

16/024086

Inventors:

- Providence RI, US
Rajiv GUPTA - Wayland MA, US
Avilash CRAMER - Lynnfield MA, US
Christopher BULL - Rehoboth MA, US
Paul WALTZ - Seekonk MA, US
Angus KINGON - Providence RI, US

International Classification:

C03B 37/012
G02B 6/08
B29C 43/00
G01T 1/20
B29C 43/58
B29D 11/00
B29K 505/02
B29K 105/16
B29K 77/00
B29K 27/12
B29K 25/00
B29C 43/18
B29K 505/08
B29L 11/00
B82Y 15/00
B29K 23/00

Abstract:

A method and apparatus to manufacture a coherent bundle of scintillating fibers is disclosed. A method includes providing a collimated bundle having a glass preform with capillaries therethrough known in the industry as a glass capillary array, and infusing the glass capillary array with a scintillating polymer or a polymer matrix containing scintillating nanoparticles.

US Patent:

20170362114, Dec 21, 2017

Filed:

Jun 19, 2017

Appl. No.:

15/626784

Inventors:

- Providence RI, US
Rajiv Gupta - Wayland MA, US
Avilash Cramer - Lynnfield MA, US
Christopher Bull - Rehoboth MA, US
Paul Waltz - Seekonk MA, US
Angus Kingon - Providence RI, US

International Classification:

C03B 37/012
G01T 1/20
B29C 43/00
B82Y 15/00
B29K 27/12

Abstract:

A method and apparatus to manufacture a coherent bundle of scintillating fibers is disclosed. A method includes providing a collimated bundle having a glass preform with capillaries therethrough known in the industry as a glass capillary array, and infusing the glass capillary array with a scintillating polymer or a polymer matrix containing scintillating nanoparticles.

US Patent:

20170176606, Jun 22, 2017

Filed:

Mar 3, 2017

Appl. No.:

15/449205

Inventors:

- Providence RI, US
Rajiv Gupta - Wayland MA, US
Avilash Cramer - Lynnfield MA, US
Christopher Bull - Rehoboth MA, US
Paul Waltz - Seekonk MA, US

International Classification:

G01T 1/20
C03B 37/012
B29D 11/00
B29C 43/58
B29C 43/00

Abstract:

A method and apparatus to manufacture a coherent bundle of scintillating fibers is disclosed. In the method and apparatus, a polymer matrix of a transparent polymer and nanoparticle scintillators is placed on top of a collimated bundle having a plurality of capillaries and pressed in a pressure vessel until the polymer matrix is forced into the capillaries. Pressure is applied via an anvil on top of the polymer matrix. To prevent fracturing of the collimated bundle during pressing, back pressure is supplied to the pressure vessel via a valve, which controls a supply of high pressure gas. Alternatively, the back pressure may also be supplied by a press (and or pressure) and support to the collimated bundle is provided by a high melting point thermoplastic. Heat may be applied to the polymer matrix via the anvil to speed the pressing operation due to the viscosity of the polymer.