Christopher M Butler

US Patent:

8256348, Sep 4, 2012

Filed:

Nov 30, 2011

Appl. No.:

13/373772

Inventors:

Howard A. Fromson - Stonington CT, US
Christopher M. Butler - Storrs CT, US
William J. Ryan - North Granby CT, US

Assignee:

Anocoil Corporation - Rockville CT

International Classification:

B41C 1/10
B41F 7/00
B41M 1/06

US Classification:

1014631, 4302731, 430302, 1014501, 101453, 101481, 101485, 101DIG 36

Abstract:

A method for preparing lithographic printing plates for on-press development, including sequentially feeding the plates to an imaging station to produce a plurality of latent image reference marks allocated among at least two margins along a respective two sides of the plate, and a latent print image within the margins. The imaged plates are transported from the imaging station to a plate bending station where the short ends of the plate are bent over. Between the imaging station and the bending station, the unimaged areas of the coating in at least two of the margins are removed to reveal the reference marks without developing the latent print image. Preferably, the reference marks are revealed while the plate is temporarily aligned in landscape orientation at stop, such as at the feeder to the bending station.

US Patent:

20210024497, Jan 28, 2021

Filed:

Mar 25, 2019

Appl. No.:

17/040479

Inventors:

- New York NY, US
Erik Alphie LaChapelle - Uncasville CT, US
Christopher Ryan Butler - Canton MA, US
Natasha Mariam Kablaoui - Newton MA, US
Michael Aaron Brodney - Newton MA, US
Laura Ann McAllister - Arlington MA, US
Qingyi Yang - Lexington MA, US
Christopher John Helal - Mystic CT, US
Damien Webb - Bottminggen, CH

International Classification:

C07D 401/14
C07D 401/12
C07D 417/14
C07D 471/04
C07D 491/107
C07D 413/14

Abstract:

The present invention provides, in part, compounds of Formula I: or an N-oxide thereof, or a pharmaceutically acceptable salt of the compound or the N-oxide, wherein: X, X, R, R, m and n are as described herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds, N-oxides, or salts, and their uses for treating M4-mediated (or M4-associated) disorders including, e.g., Alzheimer's Disease, Parkinson's Disease, schizophrenia (e.g., its cognitive and negative symptoms), pain, addiction, and a sleep disorder.

US Patent:

20160002264, Jan 7, 2016

Filed:

Dec 4, 2013

Appl. No.:

14/653549

Inventors:

- New York NY, US
Brian Thomas O'Neill - Haddam CT, US
Christopher Ryan Butler - Canton MA, US
Erik Alphie LaChapelle - Johnston RI, US

Assignee:

PFIZER INC. - New York NY

International Classification:

C07D 513/04

Abstract:

The present invention provides compounds of formula I,wherein the variables R, R, Rand b are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

US Patent:

20150376207, Dec 31, 2015

Filed:

Feb 2, 2014

Appl. No.:

14/767414

Inventors:

- New York NY, US
Brian Thomas O'Neill - Haddam CT, US
Christopher Ryan Butler - Canton MA, US
Elizabeth Mary Beck - Edinburgh, GB

Assignee:

PFIZER INC. - New York NY

International Classification:

C07D 513/04

Abstract:

The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I,and the variables Rand Rare as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.