Christopher J Calhoun

US Patent:

6391059, May 21, 2002

Filed:

Oct 16, 2000

Appl. No.:

09/673164

Inventors:

Stefan M. Lemperle - La Jolla CA
Christopher J. Calhoun - San Diego CA

Assignee:

MacroPore, Inc. - San Diego CA

International Classification:

A61F 236

US Classification:

623 235, 623 1111, 606151

Abstract:

A resorbing, flexible implant in the form of a continuous macro-porous sheet ( ) is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vitro repair. The membrane ( ) has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature, and connective tissue cells derived from the adjacent soft tissues including the periosteum, can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature, and does not collapse.

US Patent:

6531146, Mar 11, 2003

Filed:

Mar 12, 2001

Appl. No.:

09/805411

Inventors:

Christopher J. Calhoun - San Diego CA
Ralph E. Holmes - San Diego CA

Assignee:

MacroPore, Inc. - San Diego CA

International Classification:

A61F 202

US Classification:

424426, 5147723

Abstract:

Resorbable polylactide polymer scar tissue reduction barrier membranes and methods of their application are disclosed. The scar-tissue reduction barrier membranes are constructed entirely of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The scar tissue reduction barrier membranes are formed to have thicknesses on the order of microns, such as, for example, thicknesses between 10 and 300 microns. The membranes are preshaped with welding flanges and stored in sterile packaging.

US Patent:

6673362, Jan 6, 2004

Filed:

Mar 10, 2003

Appl. No.:

10/385399

Inventors:

Christopher J. Calhoun - San Diego CA
Ralph E. Holmes - San Diego CA

Assignee:

MacroPore Biosurgery, Inc. - San Diego CA

International Classification:

A61F 202

US Classification:

424426, 5147723

Abstract:

Resorbable polylactide polymer scar tissue reduction barrier membranes and methods of their application are disclosed. The scar-tissue reduction barrier membranes are constructed entirely of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The scar tissue reduction barrier membranes are formed to have thicknesses on the order of microns, such as, for example, thicknesses between 10 and 300 microns. The membranes are preshaped with welding flanges and stored in sterile packaging.

US Patent:

6712851, Mar 30, 2004

Filed:

May 25, 2001

Appl. No.:

09/865872

Inventors:

Stefan M. Lemperle - La Jolla CA
Christopher J. Calhoun - San Diego CA

Assignee:

MacroPore Biosurgery, Inc. - San Diego CA

International Classification:

A61F 202

US Classification:

623 1611, 623 111, 606 74, 606151, 606154

Abstract:

A resorbable, flexible implant in the form of a continuous macro-porous sheet is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vivo repair. The membrane has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature and connective tissue cells derived from the adjacent soft tissues including the periosteum can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature and does not collapse.

US Patent:

7104994, Sep 12, 2006

Filed:

Oct 5, 2000

Appl. No.:

10/110161

Inventors:

James Peter Amis - Carlsbad CA, US
Christopher J. Calhoun - San Diego CA, US

Assignee:

Cytori Therapeutics, Inc. - San Diego CA

International Classification:

A61B 17/58
H05B 1/00

US Classification:

606 69, 606104, 219229

Abstract:

A method, apparatus and system for applying bio-resorbable membranes or plates to bone for internal fixation of bone defects is disclosed.

US Patent:

7537782, May 26, 2009

Filed:

Feb 27, 2003

Appl. No.:

10/375451

Inventors:

Christopher J. Calhoun - San Diego CA, US
G. Bryan Cornwall - San Diego CA, US

Assignee:

Kensey Nash Corporation - Exton PA

International Classification:

A61F 2/28

US Classification:

424426, 523112, 523115, 528323, 528324, 528326, 623 1611, 623 1711, 623 2358

Abstract:

Resorbable polymer barrier membranes and methods of their applications are disclosed. In a broad embodiment, methods of governing bone growth, or preventing bone growth into a certain spatial area, includes the step of forming a spatial barrier with the present resorbable barrier membrane. The barrier membrane separates a bone-growth area and a non-bone-growth area, and prevents bone from growing into the non-growth area.

US Patent:

7592017, Sep 22, 2009

Filed:

Jul 31, 2003

Appl. No.:

10/631980

Inventors:

Christopher J. Calhoun - San Diego CA, US
Ralph E. Holmes - San Diego CA, US
Kenneth K. Kleinhenz - Lakeside CA, US

Assignee:

MAST Biosurgery AG - Zurich

International Classification:

A61K 2/00
A01N 37/18

US Classification:

424426, 424423, 514 2

Abstract:

Resorbable lactide polymer thin membranes are disclosed. The thin membranes are constructed of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The membranes are formed to have very thin thicknesses, for example, thicknesses between about 0. 010 mm and about 0. 300 mm. The membranes can be extruded from polylactide polymers having a relatively high viscosity property, can be preshaped with relatively thick portions, and can be stored in sterile packages.

US Patent:

7704520, Apr 27, 2010

Filed:

Sep 10, 2003

Appl. No.:

10/660461

Inventors:

Christopher J. Calhoun - San Diego CA, US

Assignee:

MAST Biosurgery AG - Zurich

International Classification:

A61F 2/00

US Classification:

424423

Abstract:

Resorbable polylactide polymer healing membranes and methods of their applications are disclosed. In a broad embodiment, the invention features methods for inducing proper tissue healing after an open heart surgery. In one embodiment, the methods includes a step of forming a patch with a healing membrane over the open pericardium to induce proper tissue healing and placement in other open heart surgery procedures to facilitate re-entry by the surgeon.

Address:

13496 Wyngate Pt, San Diego, CA 92130

Phone:

8582324562

VIN:

WP0AA2A99CS789218

Make:

PORSCHE

Model:

911

Year:

2012