Christopher Lange Calhoun

US Patent:

6391059, May 21, 2002

Filed:

Oct 16, 2000

Appl. No.:

09/673164

Inventors:

Stefan M. Lemperle - La Jolla CA
Christopher J. Calhoun - San Diego CA

Assignee:

MacroPore, Inc. - San Diego CA

International Classification:

A61F 236

US Classification:

623 235, 623 1111, 606151

Abstract:

A resorbing, flexible implant in the form of a continuous macro-porous sheet ( ) is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vitro repair. The membrane ( ) has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature, and connective tissue cells derived from the adjacent soft tissues including the periosteum, can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature, and does not collapse.

US Patent:

6712851, Mar 30, 2004

Filed:

May 25, 2001

Appl. No.:

09/865872

Inventors:

Stefan M. Lemperle - La Jolla CA
Christopher J. Calhoun - San Diego CA

Assignee:

MacroPore Biosurgery, Inc. - San Diego CA

International Classification:

A61F 202

US Classification:

623 1611, 623 111, 606 74, 606151, 606154

Abstract:

A resorbable, flexible implant in the form of a continuous macro-porous sheet is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vivo repair. The membrane has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature and connective tissue cells derived from the adjacent soft tissues including the periosteum can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature and does not collapse.

US Patent:

7104994, Sep 12, 2006

Filed:

Oct 5, 2000

Appl. No.:

10/110161

Inventors:

James Peter Amis - Carlsbad CA, US
Christopher J. Calhoun - San Diego CA, US

Assignee:

Cytori Therapeutics, Inc. - San Diego CA

International Classification:

A61B 17/58
H05B 1/00

US Classification:

606 69, 606104, 219229

Abstract:

A method, apparatus and system for applying bio-resorbable membranes or plates to bone for internal fixation of bone defects is disclosed.

US Patent:

8048444, Nov 1, 2011

Filed:

Jan 11, 2007

Appl. No.:

11/652724

Inventors:

Christopher J. Calhoun - Del Mar CA, US
Ralph E. Holmes - San Diego CA, US
G. Bryan Cornwall - San Diego CA, US

Assignee:

MAST Biosurgery AG - Zurich

International Classification:

A61K 9/00
A61F 2/12

US Classification:

424426, 623 8, 424450

Abstract:

An anti-adhesion membrane is placed onto an implant introduced into a surgical site of a patient to prevent post-surgical adhesions between the implant and surrounding tissue. The implant may comprise either biological material, such as a transplanted organ, or non-biological material such as a medical device. The membrane may be applied in a variety of ways. In one example, a membrane according to the present invention is shrink-wrapped around a pace-maker. In another example, a breast implant is spray-coated or dipped with the membrane material.

US Patent:

20080140451, Jun 12, 2008

Filed:

Jan 12, 2005

Appl. No.:

11/813579

Inventors:

Marc H. Hedrick - Encinitas CA, US
Christopher Calhoun - San Diego CA, US

International Classification:

G06F 19/00
C12N 5/08

US Classification:

705 3, 424 937

Abstract:

A method and apparatus for billing entities for use of a medical device, which relates to the processing of regenerative cells to facilitate at least one of hard and soft tissue formation, are described. When an operator uses the medical device, a corresponding charge is determined. Billing for usage of the medical device is performed on a periodic or per-use basis. Communication over a network facilitates remote management and servicing of the medical device. Support is provided for automatic ordering of supplies consumed by the medical device.

US Patent:

20090288753, Nov 26, 2009

Filed:

Jul 29, 2009

Appl. No.:

12/511898

Inventors:

Christopher J. Calhoun - Del Mar CA, US
Ralph E. Homes - San Diego CA, US
G. Bryan Comwall - San Diego CA, US

International Classification:

B32B 37/00

US Classification:

156 60

Abstract:

An anti-adhesion membrane is placed onto an implant introduced into a surgical site of a patient to prevent post-surgical adhesions between the implant and surrounding tissue. The implant may comprise either biological material, such as a transplanted organ, or non-biological material such as a medical device. The membrane may be applied in a variety of ways. In one example, a membrane according to the present invention is shrink-wrapped around a pace-maker. In another example, a breast implant is spray-coated or dipped with the membrane material.

US Patent:

20120221253, Aug 30, 2012

Filed:

May 9, 2012

Appl. No.:

13/467828

Inventors:

Marc H. Hedrick - Encinitas CA, US
Christopher Calhoun - San Diego CA, US

Assignee:

CYTORI THERAPEUTICS, INC. - SAN DIEGO CA

International Classification:

G06F 19/00

US Classification:

702 19

Abstract:

A method and apparatus for billing entities for use of a medical device, which relates to the processing of regenerative cells to facilitate at least one of hard and soft tissue formation, are described. When an operator uses the medical device, a corresponding charge is determined. Billing for usage of the medical device is performed on a periodic or per-use basis. Communication over a network facilitates remote management and servicing of the medical device. Support is provided for automatic ordering of supplies consumed by the medical device.

US Patent:

62804731, Aug 28, 2001

Filed:

Feb 23, 1999

Appl. No.:

9/256422

Inventors:

Stephan M. Lemperle - La Jolla CA
Christopher J. Calhoun - San Diego CA

Assignee:

MacroPore, Inc. - San Diego CA

International Classification:

A61F 202

US Classification:

623 1611

Abstract:

A resorbable, flexible implant in the form of a continuous macro-porous sheet is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vivo repair. The membrane has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature and connective tissue cells derived from the adjacent soft tissues including the periosteum can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature and does not collapse.