Christopher Carlos Gerth

US Patent:

20050110990, May 26, 2005

Filed:

Oct 15, 2004

Appl. No.:

10/966893

Inventors:

Christopher Gerth - Newport Beach CA, US
Mineo Yamakawa - Campbell CA, US

International Classification:

G01J003/44

US Classification:

356301000

Abstract:

The device and method disclosed herein concern detecting, identifying, and or quantifying analytes, such as nucleic acids, with high resolution and fast response times using surface enhanced coherent anti-Stokes Raman spectroscopy. In certain embodiments of the invention, a small number molecular sample of the analyte such as a nucleotide, passes through a microfluidic channel, microchannel, or nanochannel and sample cell that contains Raman-active surfaces, and is detected by surface enhanced, coherent anti-Stokes Raman spectroscopy (SECARS). Other embodiments of the invention concern an apparatus for analyte detection.