Christopher D Larson

US Patent:

20210321613, Oct 21, 2021

Filed:

Jun 12, 2019

Appl. No.:

17/251005

Inventors:

- Cary NC, US
Vic Prasad - Leawood KS, US
Cameron Gibb - Apex NC, US
Christopher Lynn Larson - Cary NC, US

International Classification:

A01N 43/32
C07D 341/00

Abstract:

A process for preparation of thiocyclam base and salt. A method of manufacturing N,N-dimethyl-1,2,3-trithian-5-ylainine hydrochloride is described including the steps of: providing a mixture of thiosulfuric acid S, S′[2-(dimethylamino) trimethylene] ester monosodium salt and sodium hydroxide; adding an aqueous saline solution to the mixture of thiosulfuric acid S, S′-[-(dimethylamino) trimethylene] ester monosodium salt and sodium hydroxide; separating the phases of the mixture; collecting the solids from the mixture using filtration; washing the solids with organic solvent; and drying the solids, where the dried solids are methyl-1,2,3-trithian-5-ylamine hydrochloride, and where the yield of the N,N-dimethyl-1,2,3-trithian-5-ylamine hydrochloride is increased by incorporation of a body charge of diatomaceous earth into the saline addition step, forming a mixture of the diatomaceous C earth with the composition of this step, and filtering the charged mixture through a diatomaceous earth media prior to the separation step.

US Patent:

20200157043, May 21, 2020

Filed:

Nov 15, 2019

Appl. No.:

16/685703

Inventors:

- Cary NC, US
Vic PRASAD - Leawood KS, US
Christopher Lynn LARSON - Cary NC, US
Cameron Seath GIBB - Apex NC, US
Kirit DESAI - Gujarat, IN
Ashwani GUPTA - Gujarat, IN
Girish SISODE - Gujarat, IN

Assignee:

Arysta LifeScience Inc. - Cary NC

International Classification:

C07C 253/30

Abstract:

Disclosed herein a process preparation of 2,6-dichlorobenzonitrile. A process of making high yield, high purity 2,6-dichlorobenzonitrile including the selective de-nitrochlorination of 2-chloro-6-nitrohenzonitrile by treatment of the 2-chloro-6-nitrobenzonitrile with chlorine gas.