Christopher R Shelton

US Patent:

6909029, Jun 21, 2005

Filed:

Sep 26, 2001

Appl. No.:

09/963990

Inventors:

George P. Livi - King of Prussia PA, US
Christopher Shelton - King of Prussia PA, US

Assignee:

SmithKline Beecham Corporation - Philadelphia PA

International Classification:

G01N033/00
A01K067/00
A01K067/033

US Classification:

800 3, 800 13

Abstract:

This invention relates to methods for producing a transgenic that expresses a human 7TMR pan-neuronally, such that said transgenic exhibits a known phenotype. These transgenic can be used in a variety of ways, including, but not limited to: (1) screening and identifying substances that bind to and activate particular human 7TMRs; (2) screening for substances that antagonize human 7TMR activation; (3) identifying human 7TMRs that may respond to particular substances; and (4) evaluating the specificity and efficacy of substances on human 7TMR activation.

US Patent:

20040231008, Nov 18, 2004

Filed:

Jun 18, 2004

Appl. No.:

10/871892

Inventors:

George Livi - King of Prussia PA, US
Christopher Shelton - King of Prussia PA, US

Assignee:

SmithKline Beecham Corporation

International Classification:

A01K067/033
A01K067/00

US Classification:

800/008000

Abstract:

This invention relates to methods for producing a transgenic that expresses a human 7TMR pan-neuronally, such that said transgenic exhibits a known phenotype. These transgenic can be used in a variety of ways, including, but not limited to: (1) screening and identifying substances that bind to and activate particular human 7TMRs; (2) screening for substances that antagonize human 7TMR activation; (3) identifying human 7TMRs that may respond to particular substances; and (4) evaluating the specificity and efficacy of substances on human 7TMR activation.

US Patent:

20210335141, Oct 28, 2021

Filed:

Apr 26, 2021

Appl. No.:

17/240689

Inventors:

- Carrollton TX, US
John T. Lee - Flower Mound TX, US
Jerry Crawford - Flower Mound TX, US
Steven Remis - Coppell TX, US
Christopher Shelton - McKinney TX, US

International Classification:

G09B 5/02
G07D 11/26
G06F 21/32
G09B 5/08

Abstract:

Implementations described and claimed herein provide systems and methods for improving cash management system operation. In one implementation, a method for improving cash management system operation includes detecting an intervention event in connection with user activity of a user involving a cash management system. The method determines whether the intervention event meets an intervention threshold. A customized intervention particular to the intervention event and a the user is generated when the intervention event meets the intervention threshold. The customized intervention is output for presentation to the user. The customized intervention improves the user activity involving the cash management system.

US Patent:

20150133493, May 14, 2015

Filed:

Jul 3, 2014

Appl. No.:

14/323438

Inventors:

- New York NY, US
Hakim Djaballah - Scarsdale NY, US
Yueming Li - New York NY, US
Christopher Chad Shelton - New York NY, US

International Classification:

C07D 493/04
C07D 335/06
C07D 215/20
C07D 311/56

US Classification:

514312, 549400, 514457, 549 23, 514432, 549384, 546155

Abstract:

Compounds including those of the Formula Iwhere X, R, Rand subscript t are as defined herein, useful as γ-secretase inhibitors, are provided, as are compositions comprising the compounds, as well as methods for use of the compounds for treating or preventing neurodegenerative diseases, such as, for instance, Alzheimer's disease.