Christopher D Wheeler

US Patent:

7159928, Jan 9, 2007

Filed:

Jan 7, 2005

Appl. No.:

10/905511

Inventors:

Matthew Hill - Irvine CA, US
Henrik Fisker - Newport Beach CA, US
David Woodhouse - Newport Coast CA, US
Christopher Wheeler - Newport Beach CA, US

Assignee:

Ford Global Technologies, LLC - Dearborn MI

International Classification:

B60J 5/00
B60J 9/00

US Classification:

296153, 2961467, 29614611

Abstract:

A door for use in a vehicle and including an interior panel portion having an outer boundary facing toward an interior portion of the vehicle and including an opening. An insert positioned within at least a portion of the opening.

US Patent:

7705010, Apr 27, 2010

Filed:

Feb 22, 2006

Appl. No.:

11/813461

Inventors:

Keith L. Black - Los Angeles CA, US
Christopher Wheeler - Newbury Park CA, US

Assignee:

Cedars-Sinai Medical Center - Los Angeles CA

International Classification:

A61K 31/506

US Classification:

514275

Abstract:

The invention relates to compositions, methods and kits for the treatment of cancer. ATP-dependent potassium channel agonists, salts thereof, or chemical analogs thereof, for example, minoxidil sulfate, have been found to possess anti-neoplastic properties. Administering minoxidil sulfate may prolong the life of a cancer patient; for example, a patient with a brain tumor.

US Patent:

20200400688, Dec 24, 2020

Filed:

Feb 13, 2019

Appl. No.:

16/968795

Inventors:

- Los Angeles CA, US
CHRISTOPHER WHEELER - Los Angeles CA, US

Assignee:

CEDARS-SINAI MEDICAL CENTER - Los Angeles CA

International Classification:

G01N 33/68
A61K 39/00
C07K 14/705
C07K 14/57

Abstract:

Methods and systems for diagnosing, providing prophylaxis, and treating one or more age-related neurodegeneration or pathological cognitive impairment are provided. An increased presence of CD103+ resident memory CD8+ T cells (CD8+ T) can be detected in blood sample obtained from the human subjects with one or more symptoms of loss of short-term or long-term memory, decreased ability to maintain focus, and decreased problem-solving capacity. An increased presence of CD103+ CD8+ Tcan be compared to a value obtained from one or a pool of healthy human subjects with none of the one or more symptoms. One or more of a therapeutically effective amount of: an inhibitor of cluster of differentiation (CD103), an inhibitor of perforin-1, and an inhibitor of interferon gamma (IFNγ) can be administered as treatment of age-related neurodegeneration or pathological cognitive impairment. Pathological neurodegeneration can include Parkinson's disease, multiple sclerosis, or Alzheimer' s disease.

US Patent:

20190343122, Nov 14, 2019

Filed:

May 26, 2017

Appl. No.:

16/304762

Inventors:

- Santa Monica CA, US
Christopher Wheeler - Santa Monica CA, US

International Classification:

A01N 49/00
A01N 57/16
A01N 25/00
A01N 27/00
C12N 15/82

Abstract:

Systems and methods of preventing or reducing crop damage from pests are provided. In one embodiment, the method comprises: a) applying a mating disruption tactic to a field plot; and b) disrupting expression of one or more target genes in one or more pests, wherein crop damage is reduced in the field plot. In another embodiment, the method comprises applying an attract-and-kill tactic to a field plot, wherein said attract-and-kill tactic comprises: a) applying one or more semiochemicals or factors; and b) disrupting expression of one or more target genes in one or more pests, wherein said disruption is capable of killing the one or more pests, wherein crop damage is reduced in the field plot.

US Patent:

20190082685, Mar 21, 2019

Filed:

Dec 22, 2016

Appl. No.:

16/064024

Inventors:

- Santa Monica CA, US
Pedro COELHO - Santa Monica CA, US
Christopher WHEELER - Santa Monica CA, US

International Classification:

A01N 37/02

Abstract:

Systems and methods for managing resistance to insecticidal traits and chemicals are provided. In one aspect, systems and methods are provided that: 1) delay the development of resistance to transgenic insecticidal crops and/or chemical insecticides (preemptive strategies), and 2) rescue one or more pests' susceptibility to transgenic insecticidal crops and/or chemical insecticides once pest resistance has developed (responsive strategies).