Christopher S Young

US Patent:

7553855, Jun 30, 2009

Filed:

May 14, 2007

Appl. No.:

11/748073

Inventors:

Christopher R. Young - Waltham MA, US
Charles William Rowe - Medford MA, US

Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA

International Classification:

A61K 31/47

US Classification:

514312

Abstract:

Pharmaceutical compositions including N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and methods of using such compositions are described herein.

US Patent:

8076357, Dec 13, 2011

Filed:

May 26, 2009

Appl. No.:

12/471950

Inventors:

Christopher R. Young - Waltham MA, US
Charles William Rowe - Medford MA, US

Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA

International Classification:

A61K 31/47

US Classification:

514312

Abstract:

Pharmaceutical compositions including N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and methods of using such compositions are described herein.

US Patent:

8552034, Oct 8, 2013

Filed:

Apr 7, 2011

Appl. No.:

13/081750

Inventors:

Marinus Jacobus Verwijs - Framingham MA, US
Ritu Rohit Kaushik - Watertown MA, US
Irina Nikolaevna Kadiyala - Newton MA, US
Christopher Young - Waltham MA, US

Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA

International Classification:

A61K 31/443
C07D 405/12

US Classification:

514338, 5462837

Abstract:

A pharmaceutical composition comprising Compound 1, (3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid), and at least one excipient selected from: a filler, a diluent, a disintegrant, a surfactant, a binder, a glidant and a lubricant, the composition being suitable for oral administration to a patient in need thereof to treat a CFTR mediated disease such as Cystic Fibrosis. Methods for treating a patient in need thereof include administering an oral pharmaceutical formulation of Compound 1 to the patient.

US Patent:

20020130894, Sep 19, 2002

Filed:

Mar 15, 2001

Appl. No.:

09/809618

Inventors:

Christopher Young - Waltham MA, US
Michael Langlie - Belmont MA, US

International Classification:

G06F003/00

US Classification:

345/706000, 345/764000

Abstract:

A computer-implemented system includes generating a character and an object on a portion of a World Wide Web page, causing the character to interact with the object in response to a user input, and controlling movement of the character based on identities of the character and the object. An environment, such as a room, may also be generated for the character and the object. The environment houses the character and the object.

US Patent:

20100074949, Mar 25, 2010

Filed:

Aug 13, 2009

Appl. No.:

12/583066

Inventors:

William Rowe - Medford MA, US
Patricia Hurter - Harvard MA, US
Christopher Young - Waltham MA, US
Kirk Dinehart - Holliston MA, US
Marinus Jacobus Verwijs - Framingham MA, US
Kirk Overhoff - Waltham MA, US
Peter D.J. Grootenhuis - San Diego CA, US
Martyn Botfield - Concord MA, US
Alfredo Grossi - Somerville MA, US

International Classification:

A61K 9/28
A61K 31/47
A61K 9/42
A61K 9/44
A61P 3/00
A61P 19/10

US Classification:

424467, 514312, 424474, 424476

Abstract:

The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.

US Patent:

20100087490, Apr 8, 2010

Filed:

Sep 29, 2009

Appl. No.:

12/568717

Inventors:

Christopher Young - Waltham MA, US

Assignee:

VERTEX PHARMACEUTICALS INCORPORATED - Cambridge MA

International Classification:

A61K 31/443
C07D 405/12
A61P 43/00

US Classification:

514338, 5462837

Abstract:

The present invention relates to formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid in Form I, pharmaceutical packs or kits thereof, and methods of treatment therewith.

US Patent:

20100256184, Oct 7, 2010

Filed:

Feb 18, 2010

Appl. No.:

12/708359

Inventors:

William Rowe - Medford MA, US
Patricia Hurter - Harvard MA, US
Christopher R. Young - Waltham MA, US
Kirk Dinehart - Holliston MA, US
Marinus Jacobus Verwijs - Framingham MA, US
Kirk Overhoff - Waltham MA, US
Peter D.J. Grootenhuis - San Diego CA, US
Martyn Botfield - Concord MA, US
Alfredo Grossi - Somerville MA, US
Gregor Zlokarnik - La Jolla CA, US
Fredrick F. Van Goor - San Diego CA, US

Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA

International Classification:

A61K 31/47
A61P 19/10
A61P 19/08
A61P 11/00

US Classification:

514312

Abstract:

The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.

US Patent:

20120122922, May 17, 2012

Filed:

Nov 7, 2011

Appl. No.:

13/290491

Inventors:

Christopher R. Young - Waltham MA, US
Charles William Rowe - Medford MA, US

Assignee:

Vertex Pharmaceuticals Incorporated - Cambridge MA

International Classification:

A61K 31/47
A61P 11/00
A61P 27/02
A61P 25/16
A61P 25/28
A61P 3/06
A61P 25/00

US Classification:

514312

Abstract:

Pharmaceutical compositions including N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and methods of using such compositions are described herein.