Chrysanthi Williams from Trinity, FL, age 51

Sample Chamber Volume Reducer
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US Patent:

7846715, Dec 7, 2010
Filed:

May 13, 2008
Appl. No.:

12/120139
Inventors:

Aaron M. Owens - Plymouth MN, US
Chrysanthi Williams - Minnetonka MN, US
Troy D. Nickel - Minneapolis MN, US
International Classification:

C12M 1/00
US Classification:

4352831, 4352841, 4352931, 7386371, 623911
Abstract:

An apparatus includes a chamber insert capable of being received by a sample chamber of a conditioning system. The received chamber insert reduces the volume of the sample chamber and defines a cavity that substantially surrounds a sample holder located in the sample chamber.

System And Method For Stimulation And Characterization Of Biologic Materials
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US Patent:

20090019950, Jan 22, 2009
Filed:

Jul 20, 2007
Appl. No.:

11/780729
Inventors:

David L. Dingmann - St. Paul MN, US
Frank C. Conati - Minneapolis MN, US
Troy D. Nickel - Minneapolis MN, US
Aaron M. Owens - Plymouth MN, US
Chrysanthi Williams - Minnetonka MN, US
International Classification:

G01N 1/14
US Classification:

7386302, 7386301, 7386333, 7386483
Abstract:

A multi-sample biologic material stimulation and characterization system includes individual flow paths for each sample. Each individual flow path can maintain sterile conditions and may be chemically monitored. The mean flow rate and pulsatile flow rate through each sample may be individually controlled. Pressure at the sample is controlled independently of the flow rate through downstream variable flow restrictors. An axial force may be applied to each sample. A radial force may be applied via hydrostatic pressure of chamber fluid surrounding each sample. A real-time controller manages the system and saves information gathered from the transducers and actuators of the system.

System For Mechanical Stimulation And Characterization Of Biologic Samples
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US Patent:

20130160577, Jun 27, 2013
Filed:

Dec 21, 2011
Appl. No.:

13/332495
Inventors:

Chrysanthi Williams - Minnetonka MN, US
Troy D. Nickel - Minneapolis MN, US
Brock N. Jacobites - Westborough MA, US
Harry Malkasian - Westford MA, US
Aaron M. Owens - Plymouth MN, US
International Classification:

G01N 3/00
US Classification:

738656
Abstract:

A system for applying mechanical stimulation to a biologic sample includes a first biologic sample chamber having a biologic sample holder therein, a support structure for holding the first biologic sample chamber, and a first actuator that can supply a mechanical load to a biologic sample held by the biologic sample holder. The actuator is configured to move into a first position proximate to the chamber in which the actuator can transmit the load to the biologic sample via a first transmission path that includes the biologic sample holder. A controller is configured to automatically move the first actuator into the first position.

Bioreactor Chamber
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US Patent:

20180072976, Mar 15, 2018
Filed:

Nov 17, 2017
Appl. No.:

15/816654
Inventors:

- Milford MA, US
Stefanie Vawn Biechler - Minneapolis MN, US
David Louis Dingmann - St. Paul MN, US
Charles W. Groepper - Waconia MN, US
Tomas M. Hayes - Blaine MN, US
Chrysanthi Williams - Minnetonka MN, US
International Classification:

C12M 3/00
C12M 1/00
C12M 1/12
Abstract:

A bioreactor system includes a sample chamber capable of receiving a specimen and a cover which can be placed on the chamber to enclose the specimen within the chamber. A first member is movable between (i) a closed position in which the member restricts the cover from being moved away from the chamber in a first direction, and (ii) an open position in which the member does not restrict the cover from being moved away from the chamber. When the first member is in the closed position there is a substantially liquid proof seal between the cover and the chamber.

Specimen Conditioning And Imaging System
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US Patent:

20160054403, Feb 25, 2016
Filed:

Aug 22, 2014
Appl. No.:

14/466163
Inventors:

- Milford MA, US
Jason L. Chinavare - Minnetonka MN, US
Thomas M. Hays - Blaine MN, US
Troy D. Nickel - Minneapolis MN, US
Chrysanthi Williams - Minnetonka MN, US
Anthony Blythe - Calgary, CA
Jeffrey Frank Dunn - Calgary, CA
Steven Michael Jones - Calgary, CA
Janet Lenore Ronsky - Calgary, CA
International Classification:

G01R 33/30
G01N 1/38
Abstract:

A conditioning system includes a sample chamber capable of receiving a specimen as well as first and second specimen-holding fixtures positioned within the sample chamber and configured to apply mechanical stimulation to a specimen held by the fixtures. The system has at least one port capable of providing a fluid to the sample chamber. The chamber is sized and shaped so that it can be inserted into an imaging device which can record images of a specimen held by the fixtures.

Bioreactor Chamber
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US Patent:

20150329816, Nov 19, 2015
Filed:

May 14, 2014
Appl. No.:

14/277216
Inventors:

- Milford MA, US
Stefanie Vawn Biechler - Minneapolis MN, US
David Louis Dingmann - St. Paul MN, US
Charles W. Groepper - Waconia MN, US
Thomas M. Hays - Blaine MN, US
Chrysanthi Williams - Minnetonka MN, US
Assignee:

TA INSTRUMENTS-WATERS L.L.C. - Milford MA
International Classification:

C12M 1/00
C12M 3/00
Abstract:

A bioreactor system includes a sample chamber capable of receiving a specimen and a cover which can be placed on the chamber to enclose the specimen within the chamber. A first member is movable between (i) a closed position in which the member restricts the cover from being moved away from the chamber in a first direction, and (ii) an open position in which the member does not restrict the cover from being moved away from the chamber. When the first member is in the closed position there is a substantially liquid proof seal between the cover and the chamber.

Chrysanthi Williams