Connie Lynn Ward

US Patent:

8383385, Feb 26, 2013

Filed:

Jan 19, 2011

Appl. No.:

13/009524

Inventors:

Sarah Teter - Mountain View CA, US
Connie Ward - Hamilton MO, US
Joel Cherry - Winters CA, US
Aubrey Jones - Davis CA, US
Paul Harris - Carnation WA, US
Jung Yi - Sacramento CA, US

Assignee:

Novozymes, Inc. - Davis CA

International Classification:

C12N 9/42
C12S 3/00
C12S 3/02
C12P 19/14
C11D 3/386

US Classification:

435209, 435267, 435274, 435 99, 510392

Abstract:

The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.