Constantine G Haidaris from Redington Shores, FL, age 73

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Location:

Rochester, NY

Industry:

Higher Education

Work:

University of Rochester
Associate Professor

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Polypeptides And Immunogenic Conjugates Capable Of Inducing Antibodies Against Pathogens, And Uses Thereof
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US Patent:

7815918, Oct 19, 2010
Filed:

Dec 31, 2004
Appl. No.:

10/584871
Inventors:

Francis Gigliotti - Pittsford NY, US
Terry W. Wright - West Henrietta NY, US
Constantine G. Haidaris - Rochester NY, US
Jesse Wells - Rochester NY, US
Assignee:

University of Rochester - Rochester NY
International Classification:

A61K 39/00
A61K 39/38
A61K 38/00
C07K 14/00
US Classification:

4242741, 4241851, 4241841, 514 2, 530350, 530823
Abstract:

A number of immunologically active agents are described, including an isolated protein or polypeptide that includes the amino acid sequence of SEQ ID NO: 1, immunogenic conjugates containing either the protein or polypeptide, a full-length kexin, or a full length pneumococcal surface protein A (PspA), antibodies recognizing the protein or polypeptide or the immunogenic conjugates (particularly the epitope of SEQ ID NO: 1), and nucleic acid molecules that encode the protein or polypeptide, as well as DNA constructs, expression vectors, and host cells that contain the nucleic acid molecules. Disclosed uses of the antibodies, immunogenic conjugates, and DNA constructs include inducing passive or active immunity to treat or prevent pathogen infections, particularly by a organism, in a patient.

Vaccine Utilizing An Avirulent Strain Of Salmonella Typhimurium
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US Patent:

47643706, Aug 16, 1988
Filed:

Sep 12, 1984
Appl. No.:

6/650282
Inventors:

Patricia I. Fields - Cardiff CA
Constantine G. Haidaris - San Diego CA
Frederick L. Heffron - Cardiff CA
Assignee:

Scripps Clinic and Research Foundation - La Jolla CA
International Classification:

C12N 1500
C12N 120
C12N 100
A61K 3700
US Classification:

424 93
Abstract:

A vaccine against a microbial pathogen comprised of a live, immunogenic but prototrophic and avirulent mutant strain of the selected microbial pathogen in an amount effective to confer immunity. A method of obtaining a vaccine that induces a heightened cellular and humoral immune response to one of a variety of microbial pathogens in a warm blooded animal. A method for isolation of an avirulent strain of a selected pathogenic microorganism.

Optimized Antigens Of Pneumocystis And Use Thereof
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US Patent:

20140271656, Sep 18, 2014
Filed:

Aug 6, 2012
Appl. No.:

14/237133
Inventors:

Francis Gigliotti - Pittsford NY, US
Terry W. Wright - West Henrietta NY, US
Constantine G. Haidaris - Rochester NY, US
Patricia J. Simpson-Haidaris - Rochester NY, US
Assignee:

UNIVERSITY OF ROCHESTER - Rochester NY
International Classification:

C07K 14/44
A61K 39/00
C12N 9/02
C07K 16/20
US Classification:

4241391, 530350, 536 235, 536 234, 4241911, 5303879, 435188, 4353201
Abstract:

Immunologically active agents are described, including isolated A 12 protein or polypeptides; immunogenic conjugates containing A 12 protein or polypeptide of the present invention; antibodies recognizing the A 12 protein or polypeptide or the immunogenic conjugates of the present invention; and nucleic acid molecules that encode the A 12 protein or polypeptide of the present invention, as well as DNA constructs, expression vectors, and host cells that contain the nucleic acid molecules. Disclosed uses of the antibodies, immunogenic conjugates, and DNA constructs include inducing passive or active immunity to treat or prevent pathogen infections, particularly by a organism, in a subject.

Constantine G Haidaris