Craig Linwood Attkisson

US Patent:

20100278915, Nov 4, 2010

Filed:

Apr 29, 2010

Appl. No.:

12/770486

Inventors:

James Joseph McDermott - Ashland VA, US
R. Gary Hollenbeck - Ellicott City MD, US
Craig Linwood Attkisson - Ashland VA, US

International Classification:

A61K 9/00
A61K 31/485
A61K 9/14
A61P 11/02
A61P 11/14
A61P 37/08
A61P 31/16
A61P 11/10

US Classification:

424484, 514282, 424490

Abstract:

The invention provides oral formulations for the treatment of cold and allergy symptoms. Each formulation combines an antihistamine, an antitussive, and/or a decongestant into one extended release composition. The invention further provides for methods of making and using such formulations, as well as for methods for preventing abuse or extraction of a single drug present in an oral extended release composition comprising two or more of an antihistamine, antitussive, and/or decongestant.

US Patent:

20100280059, Nov 4, 2010

Filed:

Apr 29, 2010

Appl. No.:

12/770484

Inventors:

James Joseph McDermott - Ashland VA, US
R. Gary Hollenbeck - Ellicott City MD, US
Craig Linwood Attkisson - Ashland VA, US

International Classification:

A61K 31/485
A61P 11/00
A61P 11/02
A61P 11/14

US Classification:

514282

Abstract:

The invention provides oral formulations for the treatment of cold and allergy symptoms. Each formulation combines an antihistamine, an antitussive, and/or a decongestant into one extended release composition. The invention further provides for methods of making and using such formulations, as well as for methods for preventing abuse or extraction of a single drug present in an oral extended release composition comprising two or more of an antihistamine, antitussive, and/or decongestant.

US Patent:

20100092562, Apr 15, 2010

Filed:

May 1, 2009

Appl. No.:

12/434413

Inventors:

R. Gary Hollenbeck - Ellicott City MD, US
James Joseph McDermott - Glen Allen VA, US
Craig Linwood Attkisson - Richmond VA, US

International Classification:

A61K 9/16
A61P 11/00
A61P 37/08

US Classification:

424488, 424484, 424490

Abstract:

The present invention relates to liquid sustained release suspension dosage forms. In particular, the invention encompasses sustained release compositions comprising a dispersed phase, which contains an ion-exchange matrix drug complex, a diffusion controlling membrane coating and a dispersion medium comprising an excipient capable of impeding water activity such that drug dissolution is inhibited prior to administration. Further, the invention provides for compositions wherein several active ingredients associate in a single bead in the dispersed phase, such that the abuse potential of such active ingredients is reduced. The invention also encompasses sustained release formulations of combination drugs comprising an extended release phase and an immediate release phase. The formulations of the invention may be used to treat a variety of conditions and symptoms, including those that require administration of several drugs, such as cold and allergy symptoms. In one of the embodiments, the sustained release composition combines an antihistamine, an antitussive and a decongestant. The invention further provides for methods of making and using such formulations.