Craig G Burkhart

US Patent:

6417179, Jul 9, 2002

Filed:

Oct 22, 2001

Appl. No.:

09/986237

Inventors:

Craig G. Burkhart - Toledo OH 43623
Craig N. Burkhart - Toledo OH 43623

International Classification:

A61K 3156

US Classification:

514178, 424455

Abstract:

An ear wax solution includes a detergent which is effective to treat the ear wax by a mechanism involving at least one of dissolving the ear wax, softening the ear wax, and reducing the attachment of the ear wax to the ear. The detergent is selected from anionic detergents, cationic detergents, zwitterionic detergents, ampholytic detergents, amphoteric detergents, nonionic detergents having a steroid skeleton, or mixtures thereof. The ear wax solution also includes a solvent which is water, a hydrophilic solvent, or a mixture thereof The ear wax solution also includes an alkaline material effective to make the solution alkaline. The ear wax solution further includes an ionic additive effective to increase the ionic strength of the solution.

US Patent:

6524602, Feb 25, 2003

Filed:

Oct 22, 2001

Appl. No.:

09/986209

Inventors:

Craig G. Burkhart - Toledo OH 43623
Craig N. Burkhart - Toledo OH 43623

International Classification:

A61K 3140

US Classification:

424405, 514 30, 424427

Abstract:

A formulation for the treatment of a parasitic skin disease includes a parasiticide to kill the parasite. The formulation also includes a polymer effective to increase retention of the formulation on the skin, and to reduce absorption of the formulation into the skin. Alternatively, the formulation may include a polymer such as a beta-sheet breaker peptide which is effective to increase absorption of the insecticide into the head lice and/or the eggs of the head lice. The formulation also includes a vehicle for the polymer and the parasiticide.

US Patent:

6737070, May 18, 2004

Filed:

Mar 6, 2002

Appl. No.:

10/091607

Inventors:

Craig N. Burkhart - Toledo OH 43623

International Classification:

A61K 700

US Classification:

424401, 424400, 424613, 424646, 514859, 514871, 514946, 514947

Abstract:

This invention relates to methods of increasing the efficacy of peroxides such as benzoyl peroxide in the treatment of skin conditions such as acne. In a preferred embodiment, the invention relates to methods of increasing radicals formed by peroxides on/in the skin, more specifically near/in the comedone, for topical use in dermatology. In a specific embodiment, the invention relates to the use of transitional metals such as Cu(1) and ferrous ions-to increase the efficacy of peroxides such as benzoyl peroxide. In another embodiment, the invention relates to a method by which a peroxide such as benzoyl peroxide and its activator are added to the skin surface at the same time. In another embodiment, the invention relates to the use of a more soluble form of peroxide such as benzoyl peroxide to increase its efficacy. In another embodiment, the invention relates to the addition of a side chain to a peroxide such as benzoyl peroxide so that it is activated by light. In a further embodiment, the invention relates to the addition of a tertiary amine to a peroxide such as benzoyl peroxide at the time of skin application, to improve the efficacy of the peroxide.

US Patent:

7323185, Jan 29, 2008

Filed:

May 18, 2004

Appl. No.:

10/847906

Inventors:

Craig N. Burkhart - Toledo OH, US

International Classification:

A61K 8/02
A61K 33/40
A61K 33/26

US Classification:

424401, 424400, 424613, 424646, 514859, 514871, 514946, 514947

Abstract:

This invention relates to methods of increasing the efficacy of peroxides such as benzoyl peroxide in the treatment of skin conditions such as acne. In a preferred embodiment, the invention relates to methods of increasing radicals formed by peroxides on/in the skin, more specifically near/in the comedone, for topical use in dermatology. In a specific embodiment, the invention relates to the use of transitional metals such as Cu(1) and ferrous ions to increase the efficacy of peroxides such as benzoyl peroxide. In another embodiment, the invention relates to a method by which a peroxide such as benzoyl peroxide and its activator are added to the skin surface at the same time. In another embodiment, the invention relates to the use of a more soluble form of peroxide such as benzoyl peroxide to increase its efficacy. In another embodiment, the invention relates to the addition of a side chain to a peroxide such as benzoyl peroxide so that it is activated by light. In a further embodiment, the invention relates to the addition of a tertiary amine to a peroxide such as benzoyl peroxide at the time of skin application, to improve the efficacy of the peroxide.

US Patent:

7326420, Feb 5, 2008

Filed:

Aug 12, 2004

Appl. No.:

10/917240

Inventors:

Craig G. Burkhart - Toledo OH, US
Craig N. Burkhart - Toledo OH, US

International Classification:

A61K 8/02
A61K 33/40
A61K 33/26

US Classification:

424400, 424401, 424613, 424646, 514859, 514871, 514946, 514947

Abstract:

A benzoyl peroxide composition having increased potency includes benzoyl peroxide, a tertiary amine and/or a transition metal, and a base that increases radicals formed by the peroxide.

US Patent:

20040151716, Aug 5, 2004

Filed:

Feb 2, 2004

Appl. No.:

10/770091

Inventors:

Richard Hamer - Belleville MI, US
Craig Burkhart - Toledo OH, US
Craig Burkhart - Providence RI, US

International Classification:

A61K038/46
A61K038/47
A61K038/48
A61N001/00

US Classification:

424/094630, 424/094600, 424/094610, 514/012000, 607/001000

Abstract:

Microbe mediated dermatological conditions in an organism are treated by the use of an agent which is capable of disrupting a microbial biofilm. The agent may be a chemical agent or a physical agent such as sonic energy or an electrical field. In addition, the tissue may be treated with antimicrobial compound. Also disclosed are therapeutic materials used in the method.

US Patent:

20110082124, Apr 7, 2011

Filed:

Dec 7, 2010

Appl. No.:

12/962505

Inventors:

Craig G. Burkhart - Toledo OH, US
Craig N. Burkhart - Chapel Hill NC, US

International Classification:

A61K 31/575
A61P 35/00
A61P 17/02

US Classification:

514171, 514182

Abstract:

A method of treating a lipoma involves contacting the lipoma with a detergent to dissolve the lipoma. For example, the detergent may be a cholate, deoxycholate or similar detergent. A method of treating cellulite and extra fat deposits involves contacting them with a detergent to help the dissolving of the fat tissues. A method of improving the art of lipoma and extra fat removal involves using certain detergents and controlling the pH, ionic forces and/or other factors to improve detergent action.

US Patent:

61032484, Aug 15, 2000

Filed:

May 22, 1998

Appl. No.:

9/083593

Inventors:

Craig G. Burkhart - Toledo OH
Craig N. Burkhart - Toledo OH

International Classification:

A61K 706
A01N 2500

US Classification:

424401

Abstract:

A topical preparation for applying to scalp hair for the treatment of head lice, the topical preparation including a killing agent effective to kill the head lice, a lipophilic carrier for the killing agent, the carrier including a surfactant effective to allow the topical preparation to be washed out of the hair, and the carrier having a viscosity within a range of from about 10,000 centipoise to about 85,000 centipoise at 21. degree. C. A topical therapy for head lice includes applying the topical preparation to dry scalp hair infested with head lice, and leaving the topical preparation on the hair at least about 15 minutes. The therapy preferably includes applying a second application of the topical preparation about 6-10 days after the first application.