Craig S Sass

US Patent:

20060153892, Jul 13, 2006

Filed:

Dec 20, 2005

Appl. No.:

11/313607

Inventors:

David Porter - Blountville TN, US
Craig Sass - Kingsport TN, US

International Classification:

B05D 3/02
A61F 13/00

US Classification:

424422000, 427002260

Abstract:

This invention relates to the reduction of interaction of biological systems with foreign substrates. Some applications require that the contact of a biological fluid with a foreign surface, such as a container for that fluid, have minimal interactions with that surface. Because the adsorption of proteins at surfaces mediates much biological response, minimization of protein adsorption is a goal to improve the overall biocompatibility of materials. Described herein is a technique in which silicone coatings that are cured by UV light are applied to surfaces. The silicone surface minimizes the adsorption of proteins, and because the coatings are cured by UV light, the cure is rapid and suitable for high-speed application. Additionally, because the UV treatment causes little or no heating of the substrate, this technique is especially suitable for temperature-sensitive substrates, such as those sometimes used for medical devices. The use of UV curing also allows patterned substrates to be developed.