Cynthia L Parrish

US Patent:

7504413, Mar 17, 2009

Filed:

Nov 9, 2005

Appl. No.:

11/271147

Inventors:

Xiangping Qian - Foster City CA, US
Gustave Bergnes - Pacifica CA, US
Dashyant Dhanak - West Chester PA, US
Steven D. Knight - West Chester PA, US
Nicholas D. Adams - Royersford PA, US
Cynthia A. Parrish - King of Prussia PA, US

Assignee:

Cytokinetics, Inc. - South San Francisco CA
SmithKline Beecham Corporation - Philadelphia PA

International Classification:

C07D 471/02
A61K 31/4439

US Classification:

514300, 546121

Abstract:

Provided herein are certain substituted N-phenethylbenzamide of formula V:.

US Patent:

7582668, Sep 1, 2009

Filed:

Nov 8, 2006

Appl. No.:

11/598250

Inventors:

Xiangping Qian - Foster City CA, US
Luke W. Ashcraft - San Francisco CA, US
Jianchao Wang - Foster City CA, US
Bing Yao - Millbrae CA, US
Hong Jiang - Palo Alto CA, US
Gustave Bergnes - Pacifica CA, US
Bradley P. Morgan - Moraga CA, US
Dashyant Dhanak - West Chester PA, US
Steven D. Knight - West Chester PA, US
Nicholas D. Adams - Royersford PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin J. Duffy - Philadelphia PA, US
Duke Fitch - Spring City PA, US
Rosanna Tedesco - Philadelphia PA, US

Assignee:

Cytokinetics, Incorporated - South San Francisco CA
SmithKline Beecham Corporation - Philadelphia PA

International Classification:

A61K 31/4178
C07D 403/10

US Classification:

514397, 5483147

Abstract:

Provided are compounds of Formula I and pharmaceutically acceptable salts thereof which may be useful for the treatment of cancer or other proliferative disorders.

US Patent:

7618981, Nov 17, 2009

Filed:

May 3, 2005

Appl. No.:

11/121709

Inventors:

Xiangping Qian - South San Francisco CA, US
Andrew I. McDonald - South San Francisco CA, US
Han-Jie Zhou - South San Francisco CA, US
Luke W. Ashcraft - South San Francisco CA, US
Bing Yao - South San Francisco CA, US
Hong Jiang - South San Francisco CA, US
Jennifer Kuo Chen Huang - South San Francisco CA, US
Jianchao Wang - South San Francisco CA, US
Bradley P. Morgan - South San Francisco CA, US
Gustave Bergnes - South San Francisco CA, US
Dashyant Dhanak - Philadelphia PA, US
Steven D. Knight - Philadelphia PA, US
Nicholas D. Adams - Philadelphia PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin Duffy - Philadelphia PA, US
Duke Fitch - Philadelphia PA, US
Rosanna Tedesco - Philadelphia PA, US

Assignee:

Cytokinetics, Inc. - South San Fransico CA
SmithKline Beecham Corporation - Philadelphia PA

International Classification:

C07D 471/02
A61K 31/4439

US Classification:

514300, 546121

Abstract:

Provided are compounds of Formula V and pharmaceutically acceptable salts thereof which may be useful for the treatment of cancer or other proliferative disorders.

US Patent:

7795448, Sep 14, 2010

Filed:

May 6, 2005

Appl. No.:

11/124608

Inventors:

Xiangping Qian - South San Francisco CA, US
Andrew I. McDonald - South San Francisco CA, US
Han-Jie Zhou - South San Francisco CA, US
Luke W. Ashcraft - South San Francisco CA, US
Bing Yao - South San Francisco CA, US
Hong Jiang - South San Francisco CA, US
Jennifer Kuo Chen Huang - South San Francisco CA, US
Jianchao Wang - South San Francisco CA, US
Bradley P. Morgan - South San Francisco CA, US
Gustave Bergnes - South San Francisco CA, US
Dashyant Dhanak - Philadelphia PA, US
Steven D. Knight - Philadelphia PA, US
Nicholas D. Adams - Philadelphia PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin Duffy - Philadelphia PA, US
Duke Fitch - Philadelphia PA, US
Rosanna Tedesco - Philadelphia PA, US

Assignee:

Cytokinetics, Incorporated - South San Francisco CA

International Classification:

C07D 233/64
C07D 231/12
A61K 31/415
A61K 31/4164

US Classification:

5483381, 5483751, 514399, 514406

Abstract:

Provided are compounds of Formula V and pharmaceutically acceptable salts thereof which may be useful for the treatment of cancer or other proliferative disorders.

US Patent:

8163919, Apr 24, 2012

Filed:

Jan 7, 2009

Appl. No.:

12/350114

Inventors:

Xiangping Qian - South San Francisco CA, US
Andrew I. McDonald - South San Francisco CA, US
Han-Jie Zhou - South San Francisco CA, US
Luke W. Ashcraft - South San Francisco CA, US
Bing Yao - South San Francisco CA, US
Hong Jiang - South San Francisco CA, US
Jennifer Kuo Chen Huang - South San Francisco CA, US
Jianchao Wang - South San Francisco CA, US
Bradley P. Morgan - South San Francisco CA, US
Gustave Bergnes - South San Francisco CA, US
Dashyant Dhanak - Philadelphia PA, US
Steven D. Knight - Philadelphia PA, US
Nicholas D. Adams - Philadelphia PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin Duffy - Philadelphia PA, US
Duke Fitch - Philadelphia PA, US
Rosanna Tedesco - Philadelphia PA, US

Assignee:

Cytokinetics, Incorporated - South San Francisco CA

International Classification:

C07D 471/02
A61K 31/4439

US Classification:

546121, 514300

Abstract:

Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.

US Patent:

8207340, Jun 26, 2012

Filed:

Jan 7, 2009

Appl. No.:

12/350094

Inventors:

Xiangping Qian - South San Francisco CA, US
Andrew I. McDonald - San Francisco CA, US
Han-Jie Zhou - San Francisco CA, US
Luke W. Ashcraft - South San Francisco CA, US
Bing Yao - South San Francisco CA, US
Hong Jiang - South San Francisco CA, US
Jennifer Kuo Chen Huang - South San Francisco CA, US
Jianchao Wang - South San Francisco CA, US
Bradley P. Morgan - South San Francisco CA, US
Gustave Bergnes - South San Francisco CA, US
Dashyant Dhanak - Philadelphia PA, US
Steven D. Knight - Philadelphia PA, US
Nicholas D. Adams - Philadelphia PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin Duffy - Philadelphia PA, US
Duke Fitch - Philadelphia PA, US
Rosanna Tedesco - Philadelphia PA, US

Assignee:

Cytokinetics, Incorporated - South San Francisco CA

International Classification:

C07D 471/02
A61K 31/47

US Classification:

546121, 514300

Abstract:

Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.

US Patent:

20070050409, Mar 1, 2007

Filed:

Dec 16, 2005

Appl. No.:

11/305871

Inventors:

Taras Bugir - Golden CO, US
Cynthia Parrish - Littleton CO, US
Candace Helgerson - Denver CO, US

Assignee:

Harris Corporation - Melbourne FL

International Classification:

G06F 7/00

US Classification:

707104100

Abstract:

Embodiments of systems, program products, and methods to manage content and distribution of media are provided. An embodiment of a system, for example, can include a communication network for transmitting media files, a content management server having a processor and memory coupled to the processor, a database accessible to the processor of the content management server and including media files associated with metadata records, a plurality of content management developer computers to provide content management developers with online access over the communication network to the media files and associated metadata records to thereby edit the metadata records, a plurality of user computers accessible to the communication network to provide the users with access to the media files over the communication network to thereby view and edit at least portions of respective metadata records. The system also includes content management program product stored in the memory of the content management server to manage content and distribution of media.

US Patent:

20070067427, Mar 22, 2007

Filed:

Dec 16, 2005

Appl. No.:

11/305873

Inventors:

Taras Bugir - Golden CO, US
Cynthia Parrish - Littleton CO, US
Candace Helgerson - Denver CO, US

Assignee:

Harris Corporation - Melbourne FL

International Classification:

G06F 15/173

US Classification:

709223000

Abstract:

Embodiments of systems, program products, and methods to manage content and distribution of media are provided. An embodiment of a system, for example, can include a communication network for transmitting media files, a content management server having a processor and memory coupled to the processor, a database accessible to the processor of the content management server and including media files associated with metadata records, a plurality of content management developer computers to provide content management developers with online access over the communication network to the media files and associated metadata records to thereby edit the metadata records, a plurality of user computers accessible to the communication network to provide the users with access to the media files over the communication network to thereby view and edit at least portions of respective metadata records. The system also includes content management program product stored in the memory of the content management server to manage content and distribution of media.