Daniel Leon Armstrong

US Patent:

7776582, Aug 17, 2010

Filed:

Dec 9, 2008

Appl. No.:

12/331108

Inventors:

Daniel W. Armstrong - Arlington TX, US
Jie Ding - Waunakee WI, US

Assignee:

Sigma-Aldrich Co. - St. Louis MO

International Classification:

C12P 41/00

US Classification:

435280

Abstract:

The invention relates to the use of optically enhanced chiral ionic liquids, particularly for gas chromatography and as a reaction solvent. Specific optically enhanced chiral cationic liquids are described as is a class of optically enhanced chiral anionic liquids.

US Patent:

8097721, Jan 17, 2012

Filed:

Jan 31, 2008

Appl. No.:

12/023468

Inventors:

Daniel W. Armstrong - Arlington TX, US
Junmin Huang - Piscataway NJ, US

Assignee:

Sigma-Aldrich Co. LLC - St. Louis MO

International Classification:

C07D 243/00
C07D 403/00
C07D 207/00
C07C 211/00
C07F 9/02

US Classification:

540567, 5483137, 548524, 564305, 568 17

Abstract:

Polyionic liquid salts are provided comprising polycationic or polyanionic molecules. Further provided are solvents comprising one or more polyionic liquid salts, and the use of such polyionic liquid salts as stationary phases in gas chromatography, and as a reagent in electrospray ionization-mass spectrometry (ESI-MS).

US Patent:

8168830, May 1, 2012

Filed:

Jan 31, 2007

Appl. No.:

11/701537

Inventors:

Daniel W. Armstrong - Arlington TX, US
Jared Anderson - Toledo OH, US

Assignee:

Sigma-Aldrich Co. LLC - St. Louis MO

International Classification:

C07C 217/00
C07C 213/00
C07F 9/02
C07D 233/00
C07D 211/70
C07D 207/00

US Classification:

564463, 568 9, 5483351, 548579, 564281, 546348

Abstract:

The present invention relates to diionic liquid salts of dicationic or dianionic molecules, as well as solvents comprising such diionic liquids and the use of such diionic liquids as the stationary phase in a gas chromatographic column.

US Patent:

8481722, Jul 9, 2013

Filed:

Dec 13, 2011

Appl. No.:

13/324469

Inventors:

Daniel W Armstrong - Arlington TX, US
Junmin Huang - Piscataway NJ, US

Assignee:

Sigma-Aldrich Co. LLC - St. Louis MO

International Classification:

C07D 243/04
C07D 207/04
C07C 211/44
C07F 9/02

US Classification:

540567, 548524, 564388, 568 17

Abstract:

Polyionic liquid salts are provided comprising polycationic or polyanionic molecules. Further provided are solvents comprising one or more polyionic liquid salts, and the use of such polyionic liquid salts as stationary phases in gas chromatography, and as a reagent in electrospray ionization-mass spectrometry (ESI-MS).

US Patent:

20100148126, Jun 17, 2010

Filed:

Nov 24, 2009

Appl. No.:

12/625207

Inventors:

Xiyun Guan - Arlington TX, US
Dilani A. Jayawardhana - Arlington TX, US
Daniel W. Armstrong - Arlington TX, US
Deqiang Wang - Champaign IL, US
Qitao Zhao - Arlington TX, US

Assignee:

BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM - Austin TX

International Classification:

H01B 1/12
C07D 233/00
C07K 1/00
G01N 31/00
G01R 27/08

US Classification:

252500, 5483351, 530350, 2524081, 324694

Abstract:

The present invention is a nanopore stochastic sensing system comprising modified protein pores for detection and sequencing of oligonucleotides. The system comprises a genetically modified protein pore with a variety of non-covalent bonding recognition sites to significantly slow down the translocation of ssDNA in the pores. The present invention also describes identification and application of DNA fingerprints, which are a sequence of small current modulation events for the determination of the sequence of ssDNA molecules. In separate embodiments the present invention describes a system and a method for the detection of monovalent cations, liquid explosives, water-insoluble compounds, biomolecules and oligonucleotides. The system comprising a wild-type or genetically modified protein pore with or without a molecular adaptor. Analyte samples and mixtures are added along with specially synthesized ionic liquids.

US Patent:

20110024292, Feb 3, 2011

Filed:

Jun 17, 2010

Appl. No.:

12/817597

Inventors:

Daniel W. Armstrong - Arlington TX, US
Ping Sun - Arlington TX, US
Zachary S. Breitbach - Arlington TX, US
Chunlei Wang - Plainsboro NJ, US

International Classification:

B01J 20/22
C07H 15/04
C07H 15/18
C07H 15/26
B01D 15/08
B01D 53/02
B01D 57/02

US Classification:

204451, 536120, 536 53, 536116, 536 551, 210656, 95 84

Abstract:

The present invention relates to derivatized cyclofructan compounds, compositions comprising derivatized cyclofructan compounds, and methods of using compositions comprising derivatized cyclofructan compounds for chromatographic separations of chemical species, including enantiomers. Said compositions may comprise a solid support and/or polymers comprising derivatized cyclofructan compounds.

US Patent:

20120211696, Aug 23, 2012

Filed:

Mar 30, 2012

Appl. No.:

13/435163

Inventors:

Daniel W. Armstrong - Arlington TX, US
Jared Anderson - Toledo OH, US

Assignee:

SIGMA-ALDRICH CO. LLC - St. Louis MO

International Classification:

C09K 3/00

US Classification:

2521823, 25218212

Abstract:

The present invention relates to diionic liquid salts of dicationic or dianionic molecules, as well as solvents comprising such diionic liquids and the use of such diionic liquids as the stationary phase in a gas chromatographic column.

US Patent:

20130074580, Mar 28, 2013

Filed:

Sep 24, 2012

Appl. No.:

13/625659

Inventors:

Daniel W. Armstrong - Arlington TX, US

Assignee:

SIGMA-ALDRICH CO. LLC - St. Louis MO

International Classification:

G01N 1/22

US Classification:

73 2341

Abstract:

This disclosure provides methods and devices for quantitating, separating and/or detecting water in a liquid, gas or solid sample comprising one or more chemicals, the method comprising: providing the liquid, gas or solid sample comprising water and the one or more chemicals; and exposing said liquid, gas or solid sample to at least one solid support including at least one dicationic and/or tricationic species of Formula I or II adsorbed, absorbed or immobilized on the solid support.