Daniel P Carr

US Patent:

6759520, Jul 6, 2004

Filed:

Oct 28, 1999

Appl. No.:

09/428692

Inventors:

Daniel B. Carr - Chestnut Hill MA
Andrzej W. Lipkowski - Warsaw, PL
Richard Kream - Roslindale MA
Aleksandra Misicka-Kesik - Piastow, PL

Assignee:

The New England Medical Center Hospitals, Inc. - Boston MA

International Classification:

C07K 100

US Classification:

530402, 530300, 514 2

Abstract:

The present invention provides a novel chimeric peptide containing an opioid peptide moiety and a nociceptive peptide moiety for producing analgesia.

US Patent:

6913760, Jul 5, 2005

Filed:

Aug 6, 2002

Appl. No.:

10/213584

Inventors:

Daniel B. Carr - Chestnut Hill MA, US
Andrzej W. Lipkowski - Warsaw, PL
Donald L. Wise - Belmont MA, US
Vasif Hasirci - Ankara, TR

Assignee:

New England Medical Hospitals, Inc. - Boston MA

International Classification:

A61E013/00
A61E002/00
A61K009/14

US Classification:

424422, 424423, 424426, 424428, 424484, 424485, 424486

Abstract:

The invention provides a drug delivery compositions and methods for treating pain. A drug delivery composition contains a polymer and at least two drugs sucha as an analgesic agent and an anesthetic agent.

US Patent:

7723467, May 25, 2010

Filed:

Jul 13, 2005

Appl. No.:

11/180971

Inventors:

Andrzej W. Lipkowski - Warsaw, PL
Daniel B. Carr - Chestnut Hill MA, US

Assignee:

New England Medical Center Hospitals, Inc. - Boston MA

International Classification:

A61K 38/00
A61K 9/00
A61K 8/02
A01N 25/34
A61K 38/04

US Classification:

530300, 424400, 424401, 424402, 424404, 514 2, 530327

Abstract:

The invention features an antimicrobial composition comprising a substance P peptide and methods of inhibiting growth of a microorganism by contacting the microorganism with a substance P peptide. Bacterial and fungal pathogens are inhibited by the substance P compositions.

US Patent:

8580954, Nov 12, 2013

Filed:

Mar 22, 2007

Appl. No.:

11/689931

Inventors:

Curtis Wright - Rockport MA, US
Daniel B. Carr - Chestnut Hill MA, US
Fred H. Mermelstein - Newton MA, US

Assignee:

Hospira, Inc. - Lake Forest IL

International Classification:

C07H 15/04
C07H 3/06
C08B 37/10
C08B 37/16

US Classification:

53612312

Abstract:

The present invention is directed to a pharmaceutical composition containing a unit dose of a diclofenac compound effective to induce analgesia; and a beta-cyclodextrin compound; wherein the dose of the diclofenac compound is less than 10 mg. The present invention is also directed to methods of treating a subject in need of analgesia with the pharmaceutical compositions of the invention.

US Patent:

20030032599, Feb 13, 2003

Filed:

Nov 20, 2001

Appl. No.:

09/988792

Inventors:

Andrzej Lipkowski - Warsaw, PL
Daniel Carr - Chestnut Hill MA, US

International Classification:

A61K038/08

US Classification:

514/015000

Abstract:

The invention features an antimicrobial composition comprising a substance P peptide and methods of inhibiting growth of a microorganism by contacting the microorganism with a substance P peptide. Bacterial and fungal pathogens are inhibited by the substance P compositions.

US Patent:

20060105947, May 18, 2006

Filed:

Apr 21, 2004

Appl. No.:

10/828623

Inventors:

Daniel Carr - Chestnut Hill MA, US
Andrzej Lipkowski - Warsaw, PL
Richard Kream - Roslindale MA, US
Aleksandra Misicka-Kesik - Piastow, PL

International Classification:

C07K 14/675
A61K 38/22

US Classification:

514012000, 530399000

Abstract:

The present invention provides a novel chimeric peptide containing an opioid peptide moiety and a nociceptive peptide moiety for producing analgesia

US Patent:

20060241053, Oct 26, 2006

Filed:

Aug 7, 2003

Appl. No.:

10/524343

Inventors:

Andrzej Lipkowski - Warszawa, PL
Daniel Carr - Chestnut Hill MA, US
Iwona Bonney - Somerville MA, US
Dariusz Kosson - Warsawa, PL
Aleksandra Misjecka-Kesik - Piastow, PL

International Classification:

A61K 38/10

US Classification:

514016000, 514018000

Abstract:

Application of peptides with analgesic properties as the active ingredient in devices for the direct application of medication to the site of their expected analgesic activity, particularly in the central nervous system.

US Patent:

20070232567, Oct 4, 2007

Filed:

Mar 22, 2007

Appl. No.:

11/689939

Inventors:

Curtis Wright - Rockport MA, US
Daniel B. Carr - Chestnut Hill MA, US
Fred H. Mermelstein - Newton MA, US

International Classification:

A61K 31/724
A61K 31/415
A61K 31/405
A61K 31/192
A61K 31/365

US Classification:

514 58, 514406, 514471, 514569, 514570, 514420

Abstract:

The present invention is directed to pharmaceutical compositions containing (a) a dosage of a non-steroidal anti-inflammatory drug (NSAID) effective to induce analgesia an anti-inflammatory effect, or an anti-pyretic effect and (b) a beta-cyclodextrin compound; wherein the dosage of the NSAID compound is less than the minimum approved dose for the route of administration. Additionally, the present invention is directed to methods for treating a mammal in need of an analgesic, an anti-inflammatory, or an anti-pyretic agent comprising administering the pharmaceutical composition of the present invention.