Daniel A Chenet

US Patent:

20130294972, Nov 7, 2013

Filed:

Oct 19, 2012

Appl. No.:

13/655947

Inventors:

James C. Hone - New York NY, US
Matteo Palma - New York NY, US
Daniel Alexandre Chenet - New York NY, US
Shalom J. Wind - White Plains NY, US

International Classification:

G01N 33/53

US Classification:

422 69, 430296, 4271632

Abstract:

The disclosed subject matter provides a zero-mode waveguide (ZMW) including a substrate and at least one nano-well thereon and having a bottom surface and a side wall comprising gold. A surface of the side wall is passivated with a first functional molecule comprising polyethylene glycol. The bottom surface of the nano-well can be functionalized with at least one second molecule comprising polyethylene glycol, for example, a silane-PEG molecule. The second molecule can further include a moiety, such as biotin, which is capable of binding a target biomolecule, which in turn can bind to a biomolecule of interest for single molecule fluorescence imaging analysis. Fabrication techniques of the ZMW are also provided.

US Patent:

20220326057, Oct 13, 2022

Filed:

Jun 10, 2022

Appl. No.:

17/837527

Inventors:

- Franklin Lakes NJ, US
Daniel Chenet - Jersey City NJ, US

International Classification:

G01F 1/7084
G01F 1/684
G01F 1/69

Abstract:

A flow sensor including a fluid flow path, a first sensor configured to determine a first measurement of a thermal diffusivity and/or a viscosity of a fluid in the fluid flow path, a second sensor configured to determine a second measurement of a fluid flow velocity and/or a volumetric flow rate of the fluid in the fluid flow path, and at least one processor configured to adjust the second measurement based on the first measurement. A method including receiving fluid in a fluid flow path of a flow sensor, determining a first measurement of a thermal diffusivity and/or a viscosity of the fluid in the fluid flow path, determining a second measurement of a fluid flow velocity and/or a volumetric flow rate of the fluid in the fluid flow path, and adjusting the second measurement based on the first measurement.

US Patent:

20210270653, Sep 2, 2021

Filed:

Jun 28, 2019

Appl. No.:

17/256031

Inventors:

- Franklin Lakes NJ, US
Daniel Chenet - Jersey City NJ, US

International Classification:

G01F 1/708
G01F 1/69
G01F 1/684

Abstract:

A flow sensor including a fluid flow path, a first sensor configured to determine a first measurement of a thermal diffusivity and/or a viscosity of a fluid in the fluid flow path, a second sensor configured to determine a second measurement of a fluid flow velocity and/or a volumetric flow rate of the fluid in the fluid flow path, and at least one processor configured to adjust the second measurement based on the first measurement. A method including receiving fluid in a fluid flow path of a flow sensor, determining a first measurement of a thermal diffusivity and/or a viscosity of the fluid in the fluid flow path, determining a second measurement of a fluid flow velocity and/or a volumetric flow rate of the fluid in the fluid flow path, and adjusting the second measurement based on the first measurement.

US Patent:

20150023840, Jan 22, 2015

Filed:

Jul 28, 2014

Appl. No.:

14/444793

Inventors:

- New York NY, US
James C. Hone - New York NY, US
Matteo Palma - New York NY, US
Daniel Alexandre Chenet - New York NY, US
Shalom J. Wind - White Plains NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

G01N 33/53
G02B 1/12
G02B 1/10
C23C 22/83
G02B 6/10

US Classification:

422 8211, 216 24

Abstract:

The disclosed subject matter provides a nanoaperture having a bottom surface and a side wall comprising gold. A surface of the side wall is passivated with a first functional molecule comprising polyethylene glycol. The bottom surface of the nanoaperture can be functionalized with at least one second molecule comprising polyethylene glycol, for example, a silane-PEG molecule. The second molecule can further include a moiety, such as biotin, which is capable of binding a target biomolecule, which in turn can bind to a biomolecule of interest for single molecule fluorescence imaging analysis. Fabrication techniques of the nanoaperture are also provided.