Daniel James Gibson

US Patent:

8058024, Nov 15, 2011

Filed:

Dec 15, 2008

Appl. No.:

12/316705

Inventors:

Gregory S. Schultz - Gainesville FL, US
John I. Azeke - Gainesville FL, US
Daniel J. Gibson - Gainesville FL, US
Olajompo B. Moloye - Neshanic Station NJ, US
Priscilla Lorraine Phillips - Gainesville FL, US
Weihong Tan - Gainesville FL, US
Christopher D. Batich - Gainesville FL, US

Assignee:

University of Florida Research Foundation, Inc. - Gainesville FL

International Classification:

C12Q 1/37

US Classification:

435 23

Abstract:

The subject invention provides novel devices and methods for the detection of the presence and/or activity of proteases in biological samples.

US Patent:

8551764, Oct 8, 2013

Filed:

Nov 15, 2011

Appl. No.:

13/296939

Inventors:

Gregory S. Schultz - Gainesville FL, US
John I. Azeke - Gainesville FL, US
Daniel J. Gibson - Gainesville FL, US
Priscilla Lorraine Phillips - Gainesville FL, US
Weihong Tan - Gainesville FL, US
Christopher D. Batich - Gainesville FL, US

Assignee:

University of Florida Research Foundation, Inc. - Gainesville FL

International Classification:

C12M 1/34

US Classification:

4352871, 4352887

Abstract:

The subject invention provides novel devices and methods for the detection of the presence and/or activity of proteases in biological samples.

US Patent:

20080176263, Jul 24, 2008

Filed:

Dec 7, 2007

Appl. No.:

11/952943

Inventors:

Gregory Schultz - Gainesville FL, US
John I. Azeke - Gainesville FL, US
Daniel J. Gibson - Gainesville FL, US
Olajompo Busola Moloye - Gainesville FL, US
Priscilla Lorraine Phillips - Gainesville FL, US
Weihong Tan - Gainesville FL, US
Christopher D. Batich - Gainesville FL, US

Assignee:

University of Florida Research Foundation, Inc. - Gainesville FL

International Classification:

C12Q 1/37
C12M 1/34
G01N 21/75

US Classification:

435 23, 4352871, 436172, 4352879

Abstract:

The present invention provides diagnostic methods and devices that can be used to assay a medium, such as tissue in vivo or a sample in vitro (e.g. biological sample or environmental sample), in order to determine the presence, quantity, and/or concentration ratio of one or more target analytes.

US Patent:

20120078162, Mar 29, 2012

Filed:

May 4, 2010

Appl. No.:

13/318916

Inventors:

Daniel J. Gibson - Gainesville FL, US
Sonal S. Tuli - Gainesville FL, US
Gregory S. Schultz - Gainesville FL, US

Assignee:

University of Florida Research Foundation Inc. - Gainesville FL

International Classification:

A61M 37/00

US Classification:

604 21, 604 20

Abstract:

Electromotive delivery of macromolecules can be provided using a delivery device including a first chamber for contacting a macromolecule delivery medium to a surface of a tissue or other anatomy of a patient; and a second chamber for contacting a receiving medium to the patient. A first electrode can be disposed in the first chamber so as to not directly contact the macromolecule delivery medium. A second medium having a buffering agent can be used to keep the first electrode from coming into direct contact with the macromolecule delivery medium. A second electrode can be disposed within the receiving medium in the second chamber such that the second electrode does not directly contact the patient. An electric field can be generated using the first and second electrodes in order to cause the macromolecule delivery medium to move into the tissue of interest from the first chamber of the delivery device.

US Patent:

20120135443, May 31, 2012

Filed:

Jun 28, 2010

Appl. No.:

13/376508

Inventors:

Gregory S. Schultz - Gainesville FL, US
Daniel J. Gibson - Gainesville FL, US

International Classification:

G01N 21/64

US Classification:

435 23

Abstract:

The subject invention provides novel devices and methods for the detection and quantification of neutrophil elastase activity in biological samples.

US Patent:

20120136054, May 31, 2012

Filed:

Jun 3, 2010

Appl. No.:

13/322012

Inventors:

Gregory S. Schultz - Gainesville FL, US
Daniel J. Gibson - Gainesville FL, US

International Classification:

A61K 31/22
G01N 21/64
G01N 21/62
G01N 31/22
A61P 17/02

US Classification:

514551, 436116, 422 8205, 422 8208

Abstract:

The subject invention presides novel devices and methods for the measurement of nitric oxide in biological samples, including wound fluid samples. These advantageous devices and methods can be used for clinicians to monitor the wound's nitric oxide metabolism and/or response to treatment.

US Patent:

20200397873, Dec 24, 2020

Filed:

Sep 8, 2020

Appl. No.:

17/014402

Inventors:

- Gainesville FL, US
Daniel J. Gibson - Gainesville FL, US
Gregory Scott Schultz - Gainesville FL, US

International Classification:

A61K 38/48
A61K 41/00
A61K 38/54
A61K 47/69
A61K 49/18
A61K 9/00
A61P 17/02
A61P 27/02
A61K 38/47
A61K 38/00

Abstract:

Described herein are formulations that can include one or more enzymes that can break down one or more components of scar tissue. Also provided herein are methods of treating scar tissue by administering a formulation provided herein to a subject in need thereof.

US Patent:

20200096446, Mar 26, 2020

Filed:

Nov 26, 2019

Appl. No.:

16/696002

Inventors:

- Gainesville FL, US
Daniel J. Gibson - Gainesville FL, US

International Classification:

G01N 21/64
G01N 33/543

Abstract:

Processes which require the mixing of solutions in definite proportions typically require precise equipment to measure and dispense the solutions to maintain the proportions within a tolerable range. Some processes are not amenable to precise collection, transportation, or mixing of solutions and would therefore cause the proportions to be uncontrolled. Disclosed herein are systems, devices, and methods that allow imprecise volumes of solutions to be utilized while maintaining control of the system.