Daniel F Gochberg

US Patent:

20120029340, Feb 2, 2012

Filed:

Jun 2, 2011

Appl. No.:

13/151556

Inventors:

Mark Does - Nashville TN, US
Robert Adam Horch - Nashville TN, US
Jeffrey S. Nyman - Nashville TN, US
Daniel Frank Gochberg - Nashville TN, US

Assignee:

Vanderbilt University - Nashville TN

International Classification:

A61B 5/055

US Classification:

600410

Abstract:

Systems and methods for characterizing bone structures are provided for characterizing bone structures. In the system and method, one or more H NMR or MRI signals associated with a bone structure are obtained. Thereafter one or more signal parameters are computed from the obtained signals, where each of the signal parameters comprising at least one of a relaxation rate constant or a corresponding signal amplitude associated with a component of the obtained signals defined by a Tvalue or a range of Tvalues. Finally, the mechanical properties or fracture risk for the bone structure are determined based on the computed signal parameters and stored correlation data.

US Patent:

20210116526, Apr 22, 2021

Filed:

Oct 16, 2020

Appl. No.:

17/073164

Inventors:

- Nashville TN, US
Daniel Gochberg - Nashville TN, US

International Classification:

G01R 33/483
G01R 33/48
G01R 33/54
A61B 5/055

Abstract:

In vivo methods for non-invasively imaging (or measuring without spatial localization) of neuro-electro-magnetic oscillations are achieved by a pulse sequence of radio frequency (RF) irradiation and magnetic field gradients. These RF and gradient pulses create an intermolecular zero-quantum coherence (iZQC), the frequency of which is: 1) controlled by one or more magnetic field gradients; and 2) made to match the frequency of the targeted neuro-electro-magnetic oscillation.