Daniel J Rieger

US Patent:

7109000, Sep 19, 2006

Filed:

Mar 1, 2002

Appl. No.:

10/087684

Inventors:

Shlomit R. Edinger - New Haven CT, US
John R. MacDougall - Hamden CT, US
Isabelle Millet - Milford CT, US
Karen Ellerman - Branford CT, US
David J. Stone - Guilford CT, US
Valerie Gerlach - Branford CT, US
William M. Grosse - Branford CT, US
Denise M. Lepley - Branford CT, US
Daniel K. Rieger - Branford CT, US
Catherine E. Burgess - Wethersfield CT, US
Stacie J. Casman - North Haven CT, US
Kimberly A. Spytek - New Haven CT, US
Ferenc L. Boldog - North Haven CT, US
Li Li - Branford CT, US
Muralidhara Padigaru - Branford CT, US
Vishnu Mishra - Gainesville FL, US
Meera Patturajan - Branford CT, US
Suresh G. Shenoy - Branford CT, US
Luca Rastelli - Branford CT, US
Velizar T. Tchernev - Branford CT, US
Corine A. M. Vernet - Branford CT, US
Bryan D. Zerhusen - Branford CT, US
Uriel M. Malyankar - Branford CT, US
Xiaojia Guo - Branford CT, US
Charles E. Miller - Guilford CT, US
Esha A. Gangolli - Madison CT, US

Assignee:

CuraGen Corporation - Branford CT

International Classification:

C12P 21/06
C07K 1/00

US Classification:

435 691, 530350, 536 231

Abstract:

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

US Patent:

7253266, Aug 7, 2007

Filed:

Jun 17, 2002

Appl. No.:

10/174394

Inventors:

Richard A. Shimkets - West Haven CT, US
Michael Jeffers - Branford CT, US
Sudhirdas K. Prayaga - East Haven CT, US
Ferenc L. Boldog - North Haven CT, US
Meijia Yang - East Lyme CT, US
Catherine Burgess - Wethersfield CT, US
Elma Fernandes - Branford CT, US
John L. Herrmann - Gilford CT, US
William J. LaRochelle - Madison CT, US
Henri Lichenstein - Madison CT, US
Linda Gorman - Branford CT, US
Mei Zhong - Branford CT, US
Muralidhara Padigaru - Branford CT, US
Carol E. A. Pena - New Haven CT, US
Denise M. Lepley - Branford CT, US
Daniel K. Rieger - Branford CT, US
William Grosse - Branford CT, US

Assignee:

CuraGen Corporation - Branford CT

International Classification:

C07K 14/50
A61K 38/18
A61K 38/00
G01N 33/53

US Classification:

530399, 530350, 514 12, 435975

Abstract:

The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses.

US Patent:

20030165851, Sep 4, 2003

Filed:

Nov 29, 2001

Appl. No.:

09/997425

Inventors:

Shlomit Edinger - New Haven CT, US
John MacDougal - Hamden CT, US
Isabelle Millet - Milford CT, US
Karen Ellerman - Branford CT, US
David Stone - Guilford CT, US
Valerie Gerlach - Branford CT, US
William Grosse - Branford CT, US
John Alsobrook - Madison CT, US
Denise Lepley - Branford CT, US
Daniel Rieger - Branford CT, US
Catherine Burgess - Wethersfield CT, US
Stacie Casman - North Haven CT, US
Kimberly Spytek - New Haven CT, US
Ference Boldog - North Haven CT, US
Li Li - Branford CT, US
Muralidhara Padigaru - Branford CT, US
Vishnu Mishra - Gainesville FL, US
Meera Patturajan - Branford CT, US
Suresh Shenoy - Branford CT, US
Luca Rastelli - Guilford CT, US
Velizar Tchernev - Branford CT, US
Corine Vernet - Branford CT, US
Bryan Zerhusen - Branford CT, US
Uriel Malyankar - Branford CT, US
Xiaojia (Sasha) Guo - Branford CT, US
Charles Miller - Guilford CT, US
Esha Gangolli - Madison CT, US

International Classification:

C12Q001/68
C07H021/04
C12N009/00
C12P021/02
C12N005/06

US Classification:

435/006000, 435/069100, 435/183000, 435/320100, 435/325000, 530/350000, 536/023200

Abstract:

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

US Patent:

20030199442, Oct 23, 2003

Filed:

Oct 1, 2002

Appl. No.:

10/262473

Inventors:

John Alsobrook - Madison CT, US
Catherine Burgess - Wethersfield CT, US
Linda Gorman - Branford CT, US
Xiaojia Guo - Branford CT, US
Denise Lepley - Branford CT, US
Meera Patturajan - Branford CT, US
Luca Rastelli - Guilford CT, US
Daniel Rieger - Branford CT, US
Kimberly Spytek - New Haven CT, US
Mei Zhong - Branford CT, US

International Classification:

A61K038/17
C12Q001/68
C07H021/04
C12P021/02
C12N005/06
C07K014/47
C12N009/00

US Classification:

514/012000, 435/006000, 435/069100, 435/183000, 435/320100, 435/325000, 530/350000, 536/023200

Abstract:

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving, any one of these novel human nucleic acids and proteins.

US Patent:

20030219823, Nov 27, 2003

Filed:

Sep 6, 2002

Appl. No.:

10/236104

Inventors:

John Alsobrook - Madison CT, US
Catherine Burgess - Wethersfield CT, US
Shlomit Edinger - New Haven CT, US
Valerie Gerlach - Branford CT, US
Denise Lepley - Branford CT, US
Meera Patturajan - Branford CT, US
Carol Pena - New Haven CT, US
Daniel Rieger - Branford CT, US
Richard Shimkets - Guilford CT, US
Kimberly Spytek - New Haven CT, US
Raymond Taupier - East Haven CT, US
Mei Zhong - Branford CT, US

International Classification:

G01N033/53
A61K038/17
C07K014/47
C12P021/02
C12N005/06

US Classification:

435/007100, 435/069100, 435/320100, 435/325000, 530/350000, 536/023500, 514/012000

Abstract:

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

US Patent:

20030229016, Dec 11, 2003

Filed:

Dec 2, 2002

Appl. No.:

10/307928

Inventors:

John Alsobrook - Madison CT, US
David Anderson - Branford CT, US
Ferenc Boldog - North Haven CT, US
Catherine Burgess - Wethersfield CT, US
Elina Catterton - Madison CT, US
Shlomit Edinger - New Haven CT, US
Linda Gorman - Branford CT, US
Xiaojia Guo - Branford CT, US
Weizhen Ji - Branford CT, US
Ramesh Kekuda - Norwalk CT, US
Li Li - Branford CT, US
Meera Patturajan - Branford CT, US
Daniel Rieger - Branford CT, US
Suresh Shenoy - Branford CT, US
Kimberly Spytek - New Haven CT, US
Corine Vernet - Branford CT, US
Edward Voss - Wallingford CT, US
Mei Zhong - Branford CT, US

International Classification:

A61K038/17
C07K014/47
C12P021/02
C12N005/06
G01N033/53

US Classification:

514/012000, 530/350000, 435/069100, 435/320100, 435/325000, 536/023200, 435/007100

Abstract:

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

US Patent:

20030232347, Dec 18, 2003

Filed:

Aug 1, 2002

Appl. No.:

10/211689

Inventors:

David Anderson - Branford CT, US
John Alsobrook - Madison CT, US
Ferenc Boldog - North Haven CT, US
Catherine Burgess - Wethersfield CT, US
Stacie Casman - North Haven CT, US
Shlomit Edinger - New Haven CT, US
Esha Gangolli - Madison CT, US
Linda Gorman - Branford CT, US
Xiaojia Guo - Branford CT, US
Nikolai Khramtsov - Branford CT, US
Denise Lepley - Branford CT, US
John MacDougall - Hamden CT, US
Carol Pena - New Haven CT, US
John Peyman - New Haven CT, US
Meera Patturajan - Branford CT, US
Daniel Rieger - Branford CT, US
Richard Shimkets - Guilford CT, US
Glennda Smithson - Guilford CT, US
Kimberly Spytek - New Haven CT, US
Corine Vernet - Branford CT, US
Edward Voss - Wallingford CT, US
Mei Zhong - Branford CT, US

International Classification:

C12Q001/68
C07H021/04
C12P021/02
C12N005/06
C07K014/705

US Classification:

435/006000, 435/069100, 435/320100, 435/325000, 530/350000, 536/023500

Abstract:

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

US Patent:

20040002453, Jan 1, 2004

Filed:

Dec 2, 2002

Appl. No.:

10/307719

Inventors:

John Alsobrook - Madison CT, US
David Anderson - Branford CT, US
Catherine Burgess - Wethersfield CT, US
Shlomit Edinger - New Haven CT, US
Linda Gorman - Branford CT, US
Xiaojia Guo - Branford CT, US
Weizhen Ji - Branford CT, US
Li Li - Branford CT, US
Meera Patturajan - Branford CT, US
Carol Pena - Guilford CT, US
Daniel Rieger - Branford CT, US
Suresh Shenoy - Branford CT, US
Richard Shimkets - Guilford CT, US
Kimberly Spytek - New Haven CT, US
Raymond Taupier - East Haven CT, US
Mei Zhong - Branford CT, US

International Classification:

A61K038/17
C12P021/02
C12N005/06
C07K014/47
C07H021/04

US Classification:

514/012000, 530/350000, 435/069100, 435/320100, 435/325000, 536/023200

Abstract:

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.