Daniel Ryan Rogers

US Patent:

6984643, Jan 10, 2006

Filed:

Jul 1, 2003

Appl. No.:

10/611049

Inventors:

Daisy Joe Du Bois - Palo Alto CA, US
Long Mao - San Diego CA, US
Daniel Harry Rogers - San Diego CA, US
John Patrick Williams - San Diego CA, US

Assignee:

Roche Palo Alto LLC - Palo Alto CA

International Classification:

C07D 401/12
A61K 31/506
A31P 11/06

US Classification:

514256, 514274, 514275, 544316, 544332, 544335

Abstract:

Compounds of Formula (I): wherein Aris aryl; Aris hydrogen, cycloalkyl, aryl or heteroaryl; Z is —C(═O) or a single bond; R, R, R, Rand Rare independently hydrogen or alkyl optionally substituted with hydroxy; alk is an alkylene chain of one to six carbon atoms; X is —O—, —NR(where Ris hydrogen or alkyl), (CRR)(where Rand Rare independently in each occurrence hydrogen or alkyl and m is an integer from 0 to 3), or —S(O)(wherein n is an integer from 0 to 2); or prodrugs thereof, and pharmaceutically acceptable salts thereof,are inhibitors of CCR3 useful for treating eosinophil induced diseases such as asthma.

US Patent:

7537009, May 26, 2009

Filed:

May 13, 2002

Appl. No.:

10/146088

Inventors:

Ron L. Hale - Woodside CA, US
Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel D. Rogers - Oakland CA, US
Soonho Song - Stanford CA, US
Martin J. Wensley - San Francisco CA, US
Daniel J. Myers - Mountain View CA, US
Jeffrey A. McKinney - Foster City CA, US
Reynaldo J. Quintana - Redwood City CA, US
Joshua D. Rabinowitz - Mountain View CA, US

Assignee:

Alexza Pharmaceuticals, Inc. - Mountain View CA

International Classification:

A61L 9/04

US Classification:

12820316, 12820014, 424 46

Abstract:

The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000 C. /s, thereby forming an vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10 μ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided.

US Patent:

20100294268, Nov 25, 2010

Filed:

Jul 30, 2010

Appl. No.:

12/847584

Inventors:

Martin J. WENSLEY - Los Gatos CA, US
Daniel MUFSON - Napa CA, US
Craig C. HODGES - Walnut Creek CA, US
Peter M. LLOYD - Walnut Creek CA, US
Daniel D. ROGERS - Oakland CA, US

Assignee:

ALEXZA PHARMACEUTICALS, INC. - Mountain View CA

International Classification:

A61M 11/00

US Classification:

12820014

Abstract:

A method and device are provided to generate an aerosol having a desired particle sizes, i.e., from molecular to about 10 microns, which can be used to effectively deliver a physiologically active compound to organs and tissues such as the lung, eye, mucosa and skin. The aerosol is formed through vaporization of the compound while mixing the resulting vapor with a gas, in a ratio, to form the desired particle size when a stable concentration of particles in the gas is reached.

US Patent:

20110240013, Oct 6, 2011

Filed:

Apr 1, 2011

Appl. No.:

13/078606

Inventors:

Ron L. Hale - Woodside CA, US
Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel D. Rogers - Oakland CA, US
Soonho Song - Stanford CA, US
Martin J. Wensley - San Francicso CA, US
Daniel J. Myers - Mountain View CA, US
Jeffrey A. McKinney - Foster City CA, US
Reynaldo J. Quintana - Redwood City CA, US
Joshua D. Rabinowitz - Princeton NJ, US

Assignee:

ALEXZA PHARMACEUTICALS, INC. - Mountain View CA

International Classification:

A61M 11/00

US Classification:

12820014

Abstract:

The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000 C./s, thereby forming a vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10μ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.

US Patent:

20130304620, Nov 14, 2013

Filed:

Mar 11, 2013

Appl. No.:

13/792811

Inventors:

Bruce Bower - Menlo Park CA, US
Shirley Foster - Kentfield CA, US
Steve Grove - San Jose CA, US
Margaret Mackenzie - San Anselmo CA, US
Daniel Rogers - Lafayette CA, US

Assignee:

Plastic Jungle, Inc. - San Mateo CA

International Classification:

G06Q 40/04

US Classification:

705 37

Abstract:

Techniques are provided for providing value to a user in exchange for the user's value-ascertainable item. In one technique, the user, while in a merchant's store, uses a mobile device to scan a QR code that triggers a browser application to send a request to an exchange service over a network. The request includes data that is associated with the merchant. The user provides card data of a particular gift card to the exchange service. The exchange service checks the balance of the card and sends an offer for the card to the user. If the user accepts, then the exchange service sends account information and/or a bar code to the user's mobile device. The account information or bar code can be used immediately by the user to purchase one or more items at the store.

US Patent:

20130325044, Dec 5, 2013

Filed:

May 31, 2012

Appl. No.:

13/485324

Inventors:

Andrew Chen Wang - Fremont CA, US
Daniel David Rogers - Oakland CA, US

Assignee:

MEDICAL INSTRUMENT DEVELOPMENT LABORATORIES, INC. - San Leandro CA

International Classification:

A61F 9/007
A61B 17/32
F16L 11/00

US Classification:

606161, 138109

Abstract:

Multi-stage tubing connecting a pneumatic pulse generator to a surgical cutter and for transmitting pressure pulses from the pneumatic pulse generator to the surgical cutter. The multi-stage tubing includes a first-stage and a second-stage. The first-stage has a first end connected to an output port of the pneumatic pulse generator, a second end opposite the first end, and a first inner channel for transmitting the pressure pulses to the surgical cutter. The first inner channel has a first cross-sectional area. The second-stage has a first end in pneumatic communication with the second end of the first-stage, a second end opposite the first end of the second-stage, and a second inner channel for transmitting the pressure pulses to the surgical cutter. The second inner channel has a second cross-sectional area that is different than the first cross-sectional area.

US Patent:

46225030, Nov 11, 1986

Filed:

Sep 26, 1985

Appl. No.:

6/781393

Inventors:

Leif J. Sundblom - Castro Valley CA
Daniel D. Rogers - Berkeley CA
Wayne W. Rogers - Napa CA

Assignee:

Medical Instrument Development Laboratories, Inc. - San Leandro CA

International Classification:

G05D 1500

US Classification:

318645

Abstract:

A variable pneumatic output device for use with ophthmalic micro-surgical instruments including a reversible servo motor which operates in response to instructions from an electronic control circuit. The rotatable drive shaft of the servo motor is operatively connected to the adjustable level control of a precision pressure regulator which operates between a fully open level and a fully closed level. The pressure regulator is operatively connected between a pressurized air source and the pneumatically driven micro-surgical instrument and according to the instructions of the electronic control circuitry, the servo motor, through the connecting drive to the regulator, adjusts the level of pneumatic output to the surgical instrument.

US Patent:

48102423, Mar 7, 1989

Filed:

Jul 31, 1986

Appl. No.:

6/892356

Inventors:

Leif J. Sundblom - Castro Valley CA
Daniel D. Rogers - Berkeley CA

Assignee:

Alcon Laboratories Inc. - Ft. Worth TX

International Classification:

A61M 100

US Classification:

604 28

Abstract:

There is disclosed herein a system for providing control of multiple functions needed to perform eye surgery. A microprocessor based system controls a vacuum generation system using venturis and linear valves and a pneumatic system for driving vitrectomy probes and pneumatic scissors in either a variable frequency, multicut mode or a proportional cut mode where the cutting pressure is proportional to the position of a foot operated position sensor. The frequency of the vitrectomy probe cutting action can also be controlled and the level of vacuum can be controlled from a foot operated position sensor which can also be used to turn on or off a fragmentation device. The footswitch can also be used to turn irrigation fluid on or off, and the flow rate can be controlled from a control on the front panel. By making a certain foot motion in any certain aspiration modes, reflux of the aspiration line can be controlled. The vacuum level is continuously monitored over all aspiration conditions and adjusted to stay as close as possible to the desired vacuum level.