Daniel P Rogers

US Patent:

6682716, Jan 27, 2004

Filed:

May 13, 2002

Appl. No.:

10/146515

Inventors:

Craig C. Hodges - Walnut Creek CA
Peter M. Lloyd - Walnut Creek CA
Daniel Mufson - Napa CA
Daniel D. Rogers - Oakland CA
Martin J. Wensley - San Francisco CA

Assignee:

Alexza Molecular Delivery Corporation - Palo Alto CA

International Classification:

A61K 912

US Classification:

424 45, 424 46, 424450, 424789, 514 54, 514220, 514252, 12820014, 12820315

Abstract:

The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to the delivery of drug containing aerosols having particles with a mass median aerodynamic diameter less than 1 for inhalation therapy. In a composition aspect of the present invention the drug containing aerosol comprises particles having a mass median aerodynamic diameter between 10 nm and 1. Preferably, the particles have a mass median aerodynamic diameter between 10 nm and 900 nm. More preferably, the particles have a mass median aerodynamic diameter between 10 nm and 800 nm, 10 nm and 700 nm, 10 nm and 600 nm, 10 nm and 500 nm, 10 nm and 400 nm, 10 nm and 300 nm, 10 nm and 200 nm, or 10 nm and 100 nm.

US Patent:

7766013, Aug 3, 2010

Filed:

Oct 26, 2001

Appl. No.:

10/057197

Inventors:

Martin J. Wensley - San Francisco CA, US
Daniel Mufson - Napa CA, US
Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel D. Rogers - Oakland CA, US

Assignee:

Alexza Pharmaceuticals, Inc. - Mountain View CA

International Classification:

H05B 3/00

US Classification:

12820327, 12820014, 12820326, 424 45, 424 46

Abstract:

A method and device are provided to generate an aerosol having a desired particle sizes, i. e. , from molecular to about 10 microns, which can be used to effectively deliver a physiologically active compound to organs and tissues such as the lung, eye, mucosa and skin. The aerosol is formed through vaporization of the compound while mixing the resulting vapor with a gas, in a ratio, to form the desired particle size when a stable concentration of particles in the gas is reached.

US Patent:

7942147, May 17, 2011

Filed:

May 13, 2002

Appl. No.:

10/146080

Inventors:

Craig C. Hodges - Walnut Creek CA, US
Peter M. Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel D. Rogers - Oakland CA, US
Martin J. Wensley - San Francisco CA, US

Assignee:

Alexza Pharmaceuticals, Inc. - Mountain View CA

International Classification:

H05B 3/00

US Classification:

12820327, 12820014, 12820326

Abstract:

The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a device that forms drug containing aerosols for use in inhalation therapy. In a device aspect of the present invention, a device for delivering drug containing aerosols for inhalation therapy is provided. The device includes a housing and an airway that has a gas/vapor mixing airway. The airway further includes a subassembly, which has a metallic substrate coated on its surface with a composition comprising a drug.

US Patent:

8240507, Aug 14, 2012

Filed:

Jun 20, 2008

Appl. No.:

12/214699

Inventors:

David L. Breeser - Minneapolis MN, US
Daniel J. Rogers - Lindstrom MN, US
John C. Holman - Ham Lake MN, US

Assignee:

Graco Minnesota Inc. - Minneapolis MN

International Classification:

B67B 1/00

US Classification:

222 20, 137215, 13762533, 222 22, 222 72, 222 74, 22215314

Abstract:

A valve comprises a valve cartridge, a valve stem and a valve seal. The valve cartridge comprises a generally cylindrical cartridge body, a bore extending longitudinally through the cartridge body, and an outlet passage and intermittent inlet passages extending through a side wall of the cartridge body to intersect the bore. The valve stem comprises an elongate body configured to slide within the bore, and a neck and a seal channel circumscribing the elongate body. The valve seal is seated within the seal channel. The valve stem slides within the bore to move the seal channel past the inlet passages. Portions of the cartridge body between the inlet passages retain the valve seal within the valve channel until the inlet passages are open to the neck. In one embodiment, the inlet passages form a crenelated edge. In another embodiment, the inlet passages form a ported end.

US Patent:

20030051728, Mar 20, 2003

Filed:

Oct 26, 2001

Appl. No.:

10/057198

Inventors:

Peter Lloyd - Walnut Creek CA, US
Martin Wensley - San Francisco CA, US
Daniel Mufson - Napa CA, US
Craig Hodges - Walnut Creek CA, US
Daniel Rogers - Oakland CA, US

International Classification:

A61M011/00
F23D011/00
A62B007/00

US Classification:

128/203260, 128/200140, 128/204130, 128/204250

Abstract:

A method and device are provided to generate an aerosol having a desired particle sizes, i.e., from molecular to about 10 microns, which can be used to effectively deliver a physiologically active compound to organs and tissues such as the lung, eye, mucosa and skin. The aerosol is formed through vaporization of the compound while simultaneously mixing the resulting vapor with air or other gas. The purity of the compound is maintained meet FDA requirements by closely controlling its degradant levels during vaporization.

US Patent:

20040096402, May 20, 2004

Filed:

Oct 30, 2003

Appl. No.:

10/696959

Inventors:

Craig Hodges - Walnut Creek CA, US
Peter Lloyd - Walnut Creek CA, US
Daniel Mufson - Napa CA, US
Daniel Rogers - Oakland CA, US
Martin Wensley - San Francisco CA, US

Assignee:

Alexza Molecular Delivery Corporation - Palo Alto CA

International Classification:

B29B009/00
A61L009/04
A61K009/14

US Classification:

424/046000, 264/005000

Abstract:

The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to the delivery of drug containing aerosols having particles with a mass median aerodynamic diameter less than 1 for inhalation therapy. In an aspect of the present invention the drug containing aerosol comprises particles having a mass median aerodynamic diameter between 10 nm and 1. Preferably, the particles have a mass median aerodynamic diameter between 10 nm and 900 nm. More preferably, the particles have a mass median aerodynamic diameter between 10 nm and 800 nm, 10 nm and 700 nm, 10 nm and 600 nm, 10 nm and 500 nm, 10 nm and 400 nm, 10 nm and 300 nm, 10 nm and 200 nm, or 10 nm and 100 nm.

US Patent:

20070031631, Feb 8, 2007

Filed:

Aug 4, 2005

Appl. No.:

11/197846

Inventors:

Garry Lundstrom - Forest Lake MN, US
Deborah Jaffey - Falcon Heights MN, US
Daniel Rogers - Grant MN, US

International Classification:

B32B 3/02

US Classification:

428064100

Abstract:

The invention is directed toward techniques for shielding a reflector of a data storage medium from ultra-violet (UV) and solar radiation. Reflectors comprise materials, such as silver, that may degrade and lose their reflective properties when exposed to UV light. In some cases, exposing the reflector to UV light may degrade a recording layer positioned adjacent the reflector in a recordable data storage medium. Degradation of the reflector and/or the recording layer can lead to significant data losses in the data storage medium. The techniques described herein position a blocking material adjacent the reflector in order to protect the reflector and data stored on the data storage medium from exposure to UV light. The blocking material may comprise UV absorbing properties in order to substantially eliminate transmission of UV light through the backside of a data storage medium.

US Patent:

20070258344, Nov 8, 2007

Filed:

May 4, 2006

Appl. No.:

11/418584

Inventors:

Daniel Rogers - Grant MN, US
Jathan Edwards - Afton MN, US

International Classification:

G11B 7/00

US Classification:

369112010, 369094000

Abstract:

Techniques are described for simultaneously accessing multiple layers of an optical data storage medium using optical elements. The techniques include passing light through one or more optical elements included in an optical device to generate multiple light beams with focus points on two or more layers of a multi-layer optical disk. In some cases, the optical device may include a single optical element that generates multiple light beams. In other cases, the optical device may include two or more optical elements that each generates a single light beam. In either case, the optical device may simultaneously access two or more of the layers of the optical disk. An optical element may comprise a diffractive optical element or a holographic optical element designed to accommodate the separation distance between each of the layers of a multi-layer optical disk and a power ratio for the layers of the multi-layer optical disk.