Daniel W Weinstein

US Patent:

20010025100, Sep 27, 2001

Filed:

Jan 5, 2001

Appl. No.:

09/755325

Inventors:

Daniel Weinstein - New York NY, US

Assignee:

The Rockefeller University

International Classification:

C07H021/04
C12P021/02
C12N005/06

US Classification:

536/023500, 435/325000, 435/069100, 530/381000

Abstract:

The present invention provides a vertebrate translation initiation factor (eIF-4AIII), that plays a role in the differentiation of an embryonic cell to an epidermal cell. This translation initiation factor interacts with BMP-4 in a positive regulatory loop. The nucleic acid and amino acid sequences are also disclosed. Also disclosed are methods of using the translation initiation factor, nucleic acids encoding the same, and corresponding antibodies and the like.

US Patent:

20030181704, Sep 25, 2003

Filed:

May 5, 2003

Appl. No.:

10/429997

Inventors:

Daniel Weinstein - New York NY, US

Assignee:

Rockefeller University, The - New York NY

International Classification:

C12N009/22
C07H021/04
C12P021/02
C12N005/06
C12N001/21
C12N015/74

US Classification:

536/023200, 435/069100, 435/320100, 435/325000, 435/252300, 435/199000

Abstract:

The present invention provides a vertebrate translation initiation factor (eIF-4AIII), that plays a role in the differentiation of an embryonic cell to an epidermal cell. This translation initiation factor interacts with BMP-4 in a positive regulatory loop. The nucleic acid and amino acid sequences are also disclosed. Also disclosed are methods of using the translation initiation factor, nucleic acids encoding the same, and corresponding antibodies and the like.

US Patent:

58615598, Jan 19, 1999

Filed:

Oct 17, 1997

Appl. No.:

8/953457

Inventors:

Harvey Donald Solomon - Niskayuna NY
Daniel Weinstein - San Jose CA
Ronald Edward DeLair - Niskayuna NY

Assignee:

General Electric Company - Schenectady NY

International Classification:

G01N 1900

US Classification:

73799

Abstract:

A double cantilever beam (DCB) assembly is disclosed, comprising a fracture specimen having a notch which defines first and second spaced, substantially parallel, outwardly extending beams, terminating at a closed end where crack growth occurs and extending to an open end. The beams are connected to each other along at least a portion of a facing surface of each beam by two, substantially parallel ligaments, spaced from each other on the facing surfaces of the beams. Another disclosed embodiment is a corrosive environment measuring apparatus, comprising a double cantilever beam assembly disposed in an aqueous portion of a reactor vessel, and including the features described above. The reactor vessel is often a constituent of a nuclear reactor, and the DCB assembly is often disposed in a tube which is selectively lowered into the aqueous portion of the reactor vessel. The tube is usually a local power range monitor tube.

US Patent:

53864425, Jan 31, 1995

Filed:

Jun 25, 1993

Appl. No.:

8/083140

Inventors:

Thomas P. Diaz - San Martin CA
Peter L. Andresen - Schenectady NY
William R. Catlin - Schenectady NY
Gary W. Contreras - San Jose CA
Ronald E. De Lair - Schenectady NY
William D. Miller - San Jose CA
Harvey D. Solomon - Schenectady NY
Daniel Weinstein - San Jose CA

Assignee:

General Electric Company - San Jose CA

International Classification:

G21C 1700

US Classification:

376245

Abstract:

An apparatus and a method for measuring and controlling the crack growth rate within a double cantilever beam type test specimen. The arms of the test specimen are fitted with a pressure-actuated bellows to induce a predetermined load and with a sensing assembly to provide feedback on the amount of beam displacement resulting from application of that load. In this manner a loaded test specimen may be remotely mounted and adjusted inside the reactor pressure vessel or piping of a nuclear reactor in order to maintain a stress intensity which is constant or which varies in a predetermined manner for inducing stress corrosion cracking or corrosion fatigue in the specimen.

US Patent:

61979473, Mar 6, 2001

Filed:

May 25, 1999

Appl. No.:

9/318443

Inventors:

Daniel C. Weinstein - New York NY

Assignee:

The Rockefeller University - New York NY

International Classification:

C07H 2104

US Classification:

536 235

Abstract:

The present invention provides a vertebrate translation initiation factor (eIF-4AIII), that plays a role in the differentiation of an embryonic cell to an epideimal cell. This translation initiation factor interacts with BMP-4 in a positive regulatory loop. The nucleic acid and amino acid sequences are also disclosed. Also disclosed are methods of using the translation initiation factor, nucleic acids encoding the same, and corresponding antibodies and the like.

US Patent:

53696751, Nov 29, 1994

Filed:

Jun 25, 1993

Appl. No.:

8/083141

Inventors:

Thomas P. Diaz - San Martin CA
Gary W. Contreras - San Jose CA
Gerald M. Gordon - Soquel CA
Veronica L. McCarthy - Fremont CA
Daniel Weinstein - San Jose CA

Assignee:

General Electric Company - San Jose CA

International Classification:

G21C 1700

US Classification:

376249

Abstract:

Electrically controlled load activating mechanisms that can be used inside the containment vessel of a nuclear reactor in conjunction with bellows-loaded DCB crack growth sensors installed inside the reactor pressure vessel or piping of a nuclear reactor. One mechanism is a liquid-filled, double-bellows master/slave arrangement connected by a capillary tube to transmit the loading provided by a linear motion device. Another mechanism uses a heat-resistant gas bottle that can be heated in a furnace to increase the gas pressure to expand the bellows of the DCB sensor. A third mechanism uses a pump or compressor to provide the necessary expansion force. The loading is controlled via electrical connections that do not require special pressure boundary penetrations of the containment vessel.

US Patent:

62916513, Sep 18, 2001

Filed:

Jan 12, 1999

Appl. No.:

9/228603

Inventors:

Daniel C. Weinstein - New York NY

Assignee:

The Rockerfeller University - New York NY

International Classification:

C07K 1600
C12N 512
C12P 2108

US Classification:

5303873

Abstract:

The present invention provides a unique src-family kinase (SFK) that plays a key role in the transformation of early-stage embryonic cells to mesodermal cells. Furthermore, this src-family kinase is likely to be a proto-oncogene. The nucleic acid and amino acid sequences are disclosed.

US Patent:

59522135, Sep 14, 1999

Filed:

Jan 13, 1998

Appl. No.:

9/006675

Inventors:

Daniel C. Weinstein - New York NY

Assignee:

The Rockefeller University - New York NY

International Classification:

C12N 912
C12N 120
C12N 1500
C12N 500

US Classification:

435194

Abstract:

The present invention provides a unique src-family kinase (SFK) that plays a key role in the transformation of early-stage embryonic cells to mesodermal cells. Furthermore, this src-family kinase is likely to be a proto-oncogene. The nucleic acid and amino acid sequences are disclosed.