Daniel A Welch

US Patent:

20210087233, Mar 25, 2021

Filed:

Nov 19, 2020

Appl. No.:

16/952251

Inventors:

Christopher Bryant - Burr Ridge IL, US
Joseph William Cormier - Bethesda MD, US
Daniel G. Welch - Denver CO, US

International Classification:

C07K 7/56
C07B 59/00
A61K 9/00

Abstract:

The present disclosure relates to deuterated forms of oxytocin, carbetocin and analogs thereof. The disclosed deuterated compounds may have similar biochemical potency and selectivity as the parent compound, and, in select instances, the selective deuteration may enable substantial benefits to their overall therapeutic profile, such as reduced adverse side effects with a decreased metabolic liability, extended pharmacological effective life, enhanced subject compliance, and/or may also decrease population pharmacokinetic variability. The present disclosure also includes pharmaceutical compositions of deuterated compounds, which may be used to treat various diseases and conditions.

US Patent:

20210076880, Mar 18, 2021

Filed:

Sep 11, 2020

Appl. No.:

17/019087

Inventors:

- Kent City MI, US
Daniel J. Welch - Kent City MI, US

International Classification:

A47K 3/40

Abstract:

A pre-installation method for a shower base includes obtaining a combination of layers forming the shower base where the combination of layers includes a waterproof membrane mounting surface and a subfloor facing surface opposite the waterproof membrane mounting surface. The method also includes adhering, in a remote location from an installation site, a waterproof membrane to the combination of layers forming the shower base. The method further includes water testing, in the remote location, the shower base with the adhered waterproof membrane.