Sergei Gryaznov - San Mateo CA, US Krisztina Pongracz - Oakland CA, US Daria Zielinska - Sunnyvale CA, US
International Classification:
C07H 19/16 C07H 19/12
US Classification:
536027300, 536028300, 536055300
Abstract:
Orthogonally protected 3′-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3′-amino group in the presence of the unprotected nucleoside base.
Synthesis Of Protected 3'-Amino Nucleoside Monomers
Sergei M. Gryaznov - San Mateo CA, US Krisztina Pongracz - Oakland CA, US Daria Zielinska - Sunnyvale CA, US
International Classification:
C07H 19/06 C07H 1/00 C07H 19/19
US Classification:
536 273
Abstract:
Orthogonally protected 3′-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3′-amino group in the presence of the unprotected nucleoside base.
Synthesis Of Protected 3'-Amino Nucleoside Monomers
- Foster City CA, US Krisztina Pongracz - Oakland CA, US Daria Zielinska - Emerald Hills CA, US
International Classification:
C07H 19/16 C07H 19/06 C07H 19/12 C07H 19/10
Abstract:
Orthogonally protected 3′-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3′-amino group in the presence of the unprotected nucleoside base.
Synthesis Of Protected 3'-Amino Nucleoside Monomers
- Foster City CA, US Krisztina Pongracz - Oakland CA, US Daria Zielinska - Emerald Hills CA, US
International Classification:
C07H 19/16 C07H 19/12 C07H 19/10 C07H 19/06
Abstract:
Orthogonally protected 3′-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3′-amino group in the presence of the unprotected nucleoside base.
Synthesis Of Protected 3'-Amino Nucleoside Monomers
- Menlo Park CA, US Krisztina Pongracz - Oakland CA, US Daria Zielinska - Emerald Hills CA, US
International Classification:
C07H 19/16 C07H 19/12 C07H 19/10 C07H 19/06
Abstract:
Orthogonally protected 3′-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3′-amino group in the presence of the unprotected nucleoside base.
Synthesis Of Protected 3'-Amino Nucleoside Monomers
- Menlo Park CA, US Krisztina Pongracz - Oakland CA, US Daria Zielinska - Emerald Hills CA, US
International Classification:
C07H 19/16 C07H 19/06
Abstract:
Orthogonally protected 3′-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3′-amino group in the presence of the unprotected nucleoside base.
C-Myc Antisense Oligonucleotides And Methods For Using The Same To Treat Cell-Proliferative Disorders
- Menlo Park CA, US Daria ZIELINSKA - Emerald Hills CA, US Ronald A. PRUZAN - Palo Alto CA, US Jeffrey N. LINDQUIST - Redwood City CA, US
International Classification:
C12N 15/113
Abstract:
Provided herein are antisense oligonucleotides that can effectively prevent or decrease c-myc protein expression as well as decrease overall rates of cell proliferation in in vitro and mammalian in vivo models of cell proliferative disorders as well as methods for using the same.
Synthesis Of Protected 3'-Amino Nucleoside Monomers
- Menlo Park CA, US Krisztina Pongracz - Oakland CA, US Daria Zielinska - Emerald Hills CA, US
Assignee:
Geron Corporation - Menlo Park CA
International Classification:
C07H 19/16 C07H 19/10 C07H 19/06
US Classification:
536 268, 536 2714, 536 282
Abstract:
Orthogonally protected 3′-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3′-amino group in the presence of the unprotected nucleoside base.
Polish Academy of Sciences Lodz
PhD, Organic Chemistry
Poznan University of Technology
MS, Organic Chemistry
Skills:
Drug Discovery Biotechnology Drug Development Lifesciences Technology Transfer Biochemistry Cell Biology Chemistry Assay Development Hplc Gmp Nmr Biomarkers Organic Chemistry Protein Chemistry