David P Allison

US Patent:

20060059984, Mar 23, 2006

Filed:

Sep 23, 2004

Appl. No.:

10/947799

Inventors:

Mitchel Doktycz - Knoxville TN, US
David Allison - Lenoir City TN, US

International Classification:

G01L 1/04

US Classification:

073161000

Abstract:

A coupled spring system is applied to dynamic force spectroscopy measurements. A microcantilever-mounted probe acts as a first spring, and a supported micromachined membrane acts as a second spring. The coupled spring system provides a system spring constant that is lower than either spring individually. By probing different regions of the membrane, the spring constant of the system can be varied.

US Patent:

20150044092, Feb 12, 2015

Filed:

Aug 5, 2014

Appl. No.:

14/451967

Inventors:

- Oak Ridge TN, US
Mitchel J. DOKTYCZ - Knoxville TN, US
Scott T. RETTERER - Knoxville TN, US
David P. ALLISON - Lenoir City TN, US

International Classification:

A61L 2/03
A61L 29/12
A61L 27/44
A61L 27/48
A61L 31/12
A61L 31/14

US Classification:

422 23, 523113, 523115, 4284231, 4284258, 428461, 428523, 4284744, 428458, 428447, 428492, 4284735, 428412, 4284755, 428702, 428689

Abstract:

The invention relates in various embodiments to a composite useful as e.g. a medical implant device, and a method of treating fouling, including biofouling as may occur on an implant. The composite comprises a matrix phase and a patterned phase that comprises an energetically activatable wire intermixed with the matrix phase, the wire when energetically activated, which includes thermal activation, causes modification of at least a portion of the matrix phase to treat fouling that might otherwise occur. The method of treating biofouling may be practiced on a patent while the medical implant of the invention is in situ.

US Patent:

20140093572, Apr 3, 2014

Filed:

May 4, 2012

Appl. No.:

14/114797

Inventors:

Mitchel J. Doktycz - Knoxville TN, US
David P. Allison - Lenoir City TN, US
Charles F. Barnett - Knoxville TN, US
Scott T. Retterer - Knoxville TN, US

Assignee:

UT-BATTELLE, LLC - Oak Ridge TN

International Classification:

A61K 41/00

US Classification:

424489, 424649, 424618, 424630, 424646, 424400, 424617, 424639

Abstract:

A method, composition and structure to treat fouling. In one embodiment, the method of treating fouling includes providing a structure including a first component of a base material and a second component of an energetically activated nanostructure, and applying a stimuli to the structure that effectuates an increase or decrease in the temperature of the energetically activated nanostructure. The increase or decrease in the temperature of the energetically activated nanostructure modifies the chemical and/or mechanical properties of the base material. The modifications to the chemical and/or mechanical properties of the base material obstruct fouling of the structure.