David Thuong Chau

US Patent:

20060189599, Aug 24, 2006

Filed:

Oct 17, 2003

Appl. No.:

10/531523

Inventors:

Alan Green - Hauover NH, US
Wing Keung - Wayland MA, US
Joseph Schildkraut - Chestnut Hill MA, US
David Chau - White River Junction VT, US

International Classification:

A61K 31/551
A61K 31/5415
A61K 31/519

US Classification:

514220000, 514225800, 514259410

Abstract:

Certain atypical antipsychotic medications (particularly clozapine) or combinations of medications are useful to treat alcohol or other substance abuse, particularly in the general (non-schizophrenic) population. Generally stated, one aspect of the invention features a method of treating a patient suffering from alcohol or other substance abuse by administering to the patient medication effective to rectify an abuse-associated dysfunction in the DA-mediated brain reward circuit. A second aspect of the invention features administering medication that strongly antagonizes α2 andrenergic receptors and weakly antagonizes dopamine D2 receptors. Preferably, the ratio of α2 receptor blockade to D2o receptor blockade is similar to that of clozapine. The medication may be a single compound (such as clozapine or risperidone), or it may include two or more compounds which together achieve the specified function. For example, the medication may include a first component which weakly blocks the D2 receptor (such as clozapine, quetiapine or ziprasidone or a low dose of another anti-psychotic that is a more potent D2 blocker) and a5 second component (such as clozapine, risperidone or idazoxan) which strongly blocks α2 receptors, particularly the α2C receptor. Cocktails of the two components are also disclosed.

US Patent:

20090109619, Apr 30, 2009

Filed:

Oct 25, 2007

Appl. No.:

11/924217

Inventors:

Jeffrey L. Wise - Acton MA, US
David S. Chau - Chandler AZ, US
Stephen A. Hauser - Carlisle MA, US
Pasi J. Vaananen - Waltham MA, US

Assignee:

MOTOROLA, INC. - Schaumburg IL

International Classification:

H05K 7/20

US Classification:

361695

Abstract:

A method and apparatus cooling a chassis. The apparatus includes a telecommunication shelf structure or chassis () having a top side (), bottom side (), front side () and back side (). Slots that can support boards () are oriented between the top side and the bottom side. A first set of fans () pushes air flow through the slots from the front and bottom sides of the shelf structure to the top and back sides of the shelf structure, and a second set of fans () pulls air flow through the slots from the front and bottom sides of the shelf structure to the top and back of the shelf structure. The first and second set of fans form a fault tolerant and redundant fan configuration in the telecommunication shelf structure to achieve an S-shaped air flow through the telecommunication shelf structure.