David Wadsworth Holmes

US Patent:

6605061, Aug 12, 2003

Filed:

Jun 13, 2001

Appl. No.:

09/880575

Inventors:

Robert A. VanTassel - Excelsior MN
Robert S. Schwartz - Rochester MN
David R. Holmes - Rochester MN

Assignee:

Tricardia, L.L.C. - Excelsior MN

International Classification:

A61M 5178

US Classification:

60416401, 604 9601, 604264, 604532

Abstract:

A catheter for injecting medicants into the endocardium, myocardium or other portions of the cardiovascular system is presented where the catheter has apertures therein for ejection and retraction of a needle. The catheter is designed for the apertures in the catheter to press against the tissue to be injected in the heart while the heart is beating. A needle for inserting a prescribed dose of a medicant is ejected through the aperture and a plunger, pump, or diaphragm is moved to deliver a dose of the medicant to tissue adjacent the aperture. By use of the catheter gene therapy, wherein a small does of a gene are injected into the endocardium of the right or left ventricle, can be used to grow new blood vessels in the injected area of a damaged heart. The apertures in the catheter can be spaced at a prescribed distance for the dosage of medicant to form a precise pattern of injections in the area to be treated. The catheters may be used for any treatments of a human or animal patient where injections are required in the heart, veins or arteries of the cardiovascular system.

US Patent:

6645143, Nov 11, 2003

Filed:

Sep 20, 2001

Appl. No.:

09/961564

Inventors:

Robert A. VanTassel - Excelsior MN
Robert S. Schwartz - Rochester MN
David R. Holmes - Rochester MN

Assignee:

Tricardia, L.L.C. - Excelsior MN

International Classification:

A61B 500

US Classification:

600300, 600486, 600505, 600500, 600549

Abstract:

A medical monitoring apparatus designed to be implanted in the vascular system is capable of sensing and transmitting via a telemetry link to an external monitor both pressure and temperature information. An internally or externally powered microcircuit component is supported on a stent-like structure and adapted to be placed in the vascular system. Placement in the ventricular septum permits measurement of pressure and temperature in the left ventricle without introducing thrombus generating materials in the left ventricle.

US Patent:

6652555, Nov 25, 2003

Filed:

Aug 18, 2000

Appl. No.:

09/642291

Inventors:

Robert A. VanTassel - Excelsior MN
Robert G. Hauser - Long Lake MN
Robert Schwartz - Rochester MN
David Holmes - Rochester MN
Gregg S. Sutton - Maple Grove MN
Thomas E. Borillo - Plymouth MN
Jeffrey Welch - New Hope MN

Assignee:

Atritech, Inc. - Minneapolis MN

International Classification:

A61M 2900

US Classification:

606200, 606151, 623 237, 128898

Abstract:

A membrane applied to the ostium of an atrial appendage is disclosed. The membrane prevents blood clots in the atrial appendage from escaping therefrom and entering the blood stream which can result in a blocked blood vessel, leading to strokes and heart attacks. The membrane may be permeable or impermeable with respect to blood flow. The membrane is configured to extend over the ostium of the left atrial appendage. The membrane has an outer periphery with a dimension larger than a corresponding dimension of the ostium. Securement means is provided to secure the outer periphery of the membrane in direct engagement with the atrial wall surrounding the ostium. The securement means may located between the membrane and the atrial wall, or the securement means may extend distally from the membrane through the ostium.

US Patent:

6652556, Nov 25, 2003

Filed:

Oct 26, 2000

Appl. No.:

09/697628

Inventors:

Robert A. VanTassel - Excelsior MN
Robert G. Hauser - Long Lake MN
Robert Schwartz - Rochester MN
David Holmes - Rochester MN
Gregg S. Sutton - Maple Grove MN
Thomas E. Borillo - Plymouth MN
Jeffrey Welch - New Hope MN

Assignee:

Atritech, Inc. - Minneapolis MN

International Classification:

A61M 2900

US Classification:

606200

Abstract:

Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure comprising a plurality of fingers which are radially outwardly expandable with respect to a longitudinal axis to permanently engage the interior wall of the left atrial appendage, wherein the filtering membrane is attached to the support structure extending across the ostium of the left atrial appendage.

US Patent:

6689150, Feb 10, 2004

Filed:

Jul 11, 2000

Appl. No.:

09/614091

Inventors:

Robert A. VanTassel - Excelsior MN
Robert G. Hauser - Long Lake MN
Robert Schwartz - Rochester MN
David Holmes - Rochester MN
Gregg S. Sutton - Maple Grove MN
Thomas E. Borillo - Plymouth MN
Jeffrey Welch - New Hope MN

Assignee:

Atritech, Inc. - Minneapolis MN

International Classification:

A61M 2900

US Classification:

606200, 604500

Abstract:

Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage. The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e. g. , an expansion balloon, to pass therethrough, and wherein the opening is resiliently biased towards the first size.

US Patent:

6969373, Nov 29, 2005

Filed:

Sep 28, 2001

Appl. No.:

09/967681

Inventors:

Robert S. Schwartz - Excelsior MN, US
Robert A. Van Tassel - Excelsior MN, US
David R. Holmes - Excelsior MN, US

Assignee:

Tricardia, LLC - Excelsior MN

International Classification:

A61M005/178
A61M001/00
A61B017/00

US Classification:

60417003, 604152, 60416401, 60416405, 606 1

Abstract:

A medical device is provided having a needle or a catheter, insertable into a living body, which defines a plurality of holes in fluid communication with a central lumen. The holes may be of various patterns located and angled to create a desired injectate cloud pattern when an injectate is forced through the central lumen and through the plurality of holes. One embodiment provides various designs including a moveable sheath or stylet used to selectively occlude one or more of the holes while in use, thereby providing an operating physician a way to manipulate the cloud pattern anytime during the introduction of the injectate. A reducer may be used in conjunction with these needles which provides an increased degree of control when injecting very small quantities of fluid.

US Patent:

7727189, Jun 1, 2010

Filed:

Aug 19, 2003

Appl. No.:

10/644388

Inventors:

Robert A VanTassel - Excelsior MN, US
Robert G Hauser - Long Lake MN, US
Robert Schwartz - Rochester MN, US
David Holmes - Rochester MN, US
Gregg S Sutton - Maple Grove MN, US
Thomas E Borillo - Plymouth MN, US
Jeffrey Welch - New Hope MN, US

Assignee:

Atritech, Inc. - Plymouth MN

International Classification:

A61M 29/00

US Classification:

604104

Abstract:

Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure comprising a plurality of fingers which are radially outwardly expandable with respect to a longitudinal axis to permanently engage the interior wall of the left atrial appendage, wherein the filtering membrane is attached to the support structure extending across the ostium of the left atrial appendage.

US Patent:

8027993, Sep 27, 2011

Filed:

Dec 28, 2006

Appl. No.:

11/646654

Inventors:

David Holmes - Bethesda MD, US
Gary Christoph - Columbia MD, US

Assignee:

Teradota US, Inc. - Dayton OH

International Classification:

G06F 17/30

US Classification:

707783, 726 27, 726 30

Abstract:

Techniques for establishing and enforcing row level database security are presented. Qualifiers are used to uniquely identify particular rows of a database table. The qualifiers are selectively combined to generate a hash value. The hash value is associated with a user. The user is permitted to accesses selective rows of the database table in response to the rows represented in the hash value, which is associated with the user.