David B Keys

US Patent:

20170081712, Mar 23, 2017

Filed:

Sep 22, 2016

Appl. No.:

15/273200

Inventors:

- Carlsbad CA, US
Shoulian DONG - Mountain View CA, US
Theodore E. STRAUB - Lexington MA, US
David N. KEYS - Alameda CA, US

International Classification:

C12Q 1/68
G01N 27/30
G01N 27/414

Abstract:

A system for detecting one or more target molecules includes a reaction device and a temperature controller. The reaction device comprises a plurality of reaction sites and plurality of field effect transistors corresponding to the plurality of reaction sites. At least two of the reaction sites may receive a reaction solution including two target molecules. The temperature controller is configured to control a temperature of at least one of the reaction sites or the reaction solution received by the at least one reaction site. At least some of the reaction sites may receive a reagent supporting an amplification reaction. When the reaction is subjected to an amplification assay, an amplified product is produced in the at least some of the reaction sites. The plurality of field effect transistors are configured to detect at least one of the amplified products.

US Patent:

20160251707, Sep 1, 2016

Filed:

Mar 1, 2016

Appl. No.:

15/057443

Inventors:

- Carlsbad CA, US
Kelly Li - San Jose CA, US
Andreas Tobler - Fremont CA, US
Caifu Chen - Palo Alto CA, US
David Keys - Alameda CA, US

International Classification:

C12Q 1/68

Abstract:

This disclosure relates to methods and kits for karyotyping in which chromosomes are interrogated by amplifying loci that are not within copy number variable regions thereof.