David Ben Kita

US Patent:

6864052, Mar 8, 2005

Filed:

Jan 6, 2000

Appl. No.:

09/479608

Inventors:

Radoje Drmanac - Palo Alto CA, US
Snezana Drmanac - Palo Alto CA, US
David Kita - Foster City CA, US
Cory Cooke - Newark CA, US
Chongjun Xu - San Jose CA, US

Assignee:

Callida Genomics, Inc. - Sunnyvale CA

International Classification:

C12Q001/68
C07H021/04
C07H021/02
C12P019/34

US Classification:

435 6, 435 911, 435 9152, 536 231, 536 2432, 536 253

Abstract:

The invention provides methods for sequencing by hybridization (SBH) using pools of probes that allow greater efficiency in conducting SBH by reducing the number of separate measurements of hybridization signals required to identify each particular nucleotide in a target nucleic acid sequence. The invention also provides pools and sets of pools of probes, as well as methods of generating pools of probes.

US Patent:

6909749, Jun 21, 2005

Filed:

Jul 15, 2002

Appl. No.:

10/196739

Inventors:

Edward R. Ratner - Sunnyvale CA, US
Adityo Prakash - Redwood Shores CA, US
David B. Kita - Milpitas CA, US

Assignee:

PTS Corporation - San Jose CA

International Classification:

H04N007/12

US Classification:

37524016

Abstract:

In a method and apparatus for predicting and coding motion vectors in a video compression scheme, an ordered list of segments for a reference frame is used to create a hierarchy of segments with a plurality of levels. Motion vectors for segments in the top level are entropy coded, and these vectors are used to predict vectors for segments at the next level. Residual vectors are entropy coded to correct these predictions, and the process of prediction from above and coding residuals continues recursively down through the hierarchy of segment levels. Information about the previous motion of segments may be exploited in the prediction process. In a complementary method and apparatus for decoding motion vectors, the same segment hierarchy is used to predict motion vectors by the same method used during encoding, and these predicted vectors are added to residual motion vectors to reconstruct the actual motion vectors.

US Patent:

6964868, Nov 15, 2005

Filed:

Jan 28, 1999

Appl. No.:

09/297648

Inventors:

Lewis T. Williams - Tiburon CA, US
Jaime Escobedo - Alamo CA, US
Michael A. Innis - Moraga CA, US
Pablo Dominguez Garcia - San Francisco CA, US
Julie Sudduth-Klinger - Kensington CA, US
Christoph Reinhard - Alameda CA, US
Klaus Giese - Berlin, DE
Filippo Randazzo - San Francisco CA, US
Giulia C. Kennedy - San Francisco CA, US
David Pot - San Francisco CA, US
Altaf Kassam - Oakland CA, US
George Lamson - Moraga CA, US
Radoje Drmanac - Palo Alto CA, US
Radomir Crkvenjakov - Sunnyvale CA, US
Mark Dickson - Hollister CA, US
Snezana Drmanac - Palo Alto CA, US
Ivan Labat - San Francisco CA, US
Dena Leshkowitz - Sunnyvale CA, US
David Kita - Foster City CA, US
Veronica Garcia - Sunnyvale CA, US
Lee William Jones - San Jose CA, US

Assignee:

Nuvelo, Inc. - Sunnyvale CA

International Classification:

C12N005/10
C12N015/63
C12N001/21
C12N015/12

US Classification:

435325, 4353201, 4352523, 536 235

Abstract:

This invention relates to novel human polynucleotides and variants thereof, their encoded polypeptides and variants thereof, to genes corresponding to these polynucleotides and to proteins expressed by the genes. The invention also relates to diagnostic and therapeutic agents employing such novel human polynucleotides, their corresponding genes or gene products, e. g. , these genes and proteins, including probes, antisense constructs, and antibodies.

US Patent:

6970790, Nov 29, 2005

Filed:

Oct 14, 2004

Appl. No.:

10/967011

Inventors:

David Kita - Milpitas CA, US
Somalee Datta - Menlo Park CA, US
Adityo Prakash - Fremont CA, US
Eniko Fodor - Fremont CA, US

Assignee:

Verseon, LLC - Milpitas CA

International Classification:

C12Q001/00

US Classification:

702 22, 702 19

Abstract:

A method and apparatus for analysis of molecular combinations featuring two or more molecular subsets is described. The computational method estimates the electrostatic affinity of the system via utilization of a basis expansion representing charge density and electrostatic potential functions associated with the first and second molecular subsets in a coordinate system. An electrostatic affinity, representing a correlation of the charge density and electrostatic potential functions of the first and second molecular subsets, is computed via suitable application of translation and rotation operators to the basis expansion coefficients over a sequence of different sampled configurations for the molecular combination. The method may also be combined with other methods for computation of shape complementarity in determining a composite or augmented score reflecting both electrostatic affinity and shape complementarity for configurations of a molecular combination.

US Patent:

6985527, Jan 10, 2006

Filed:

Mar 7, 2002

Appl. No.:

10/093072

Inventors:

Michial Gunter - Fremont CA, US
David B. Kita - Milpitas CA, US
Oliver W. Shih - San Jose CA, US
Carroll Philip Gossett - Mt. View CA, US

Assignee:

PTS Corporation - San Jose CA

International Classification:

H04N 7/18

US Classification:

37524016, 37524017

Abstract:

A method and apparatus for estimating the motion of an image region (the “center” region) from a source video frame to a target video frame. The motion estimation is locally constrained in that the estimated motion of the “center region” is affected by the estimated motion of neighboring regions. Advantageously, this may reduce common motion matching problems such as false and ambiguous matches. In one embodiment, the locally-constrained motion estimation may be implemented by biasing an error map of the center region using error maps of the neighboring regions.

US Patent:

7099513, Aug 29, 2006

Filed:

Jun 18, 2002

Appl. No.:

10/175510

Inventors:

Schuyler Cullen - Palo Alto CA, US
Edward R. Ratner - Sunnyvale CA, US
Rasmus Larsen - San Francisco CA, US
David B. Kita - Milpitas CA, US

Assignee:

PTS Corporation - San Jose CA

International Classification:

G06K 9/36

US Classification:

382239, 382251

Abstract:

A process and apparatus for allocating bits between the stages of a multi-stage digital image compression scheme with quantizer feedback is disclosed. The process selects a quantization schedule (from a finite number of possibilities) for all stages that minimizes an estimate of total distortion while keeping total bit demand below a constraint; uses said schedule to actually quantize one stage of the compression scheme; selects a new quantization schedule for the remaining stages using estimates for distortion and bit demand that are updated to reflect the quantization of the previous stage; actually quantizes the next stage according to the new quantization schedule; and continues recursively until it has chosen an actual quantization scale for every stage of the compression scheme.

US Patent:

7122373, Oct 17, 2006

Filed:

May 13, 1999

Appl. No.:

09/313292

Inventors:

Lewis T. Williams - Tiburon CA, US
Jaime Escobedo - Alamo CA, US
Michael A. Innis - Moraga CA, US
Pablo Dominguez Garcia - San Francisco CA, US
Julie Sudduth-Klinger - Kensington CA, US
Christoph Reinhard - Alameda CA, US
Klaus Giese - Berlin, DE
Filippo Randazzo - San Francisco CA, US
Giulia C. Kennedy - San Francisco CA, US
David Pot - San Francisco CA, US
Altaf Kassam - Oakland CA, US
George Lamson - Moraga CA, US
Radoje Drmanac - Palo Alto CA, US
Radomir Crkvenjakov - Sunnyvale CA, US
Mark Dickson - Hollister CA, US
Snezana Drmanac - Palo Alto CA, US
Ivan Labat - Sunnyvale CA, US
Dena Leshkowitz - Sunnyvale CA, US
David Kita - Foster City CA, US
Veronica Garcia - Sunnyvale CA, US
Lee William Jones - Sunnyvale CA, US

Assignee:

Nuvelo, Inc. - Sunnyvale CA

International Classification:

C12N 5/10
C12N 15/63
C12N 15/11

US Classification:

435325, 4353201, 536 235

Abstract:

This invention relates to novel human polynucleotides and variants thereof, their encoded polypeptides and variants thereof, to genes corresponding to these polynucleotides and to proteins expressed by the genes. The invention also relates to diagnostic and therapeutic agents employing such novel human polynucleotides, their corresponding genes or gene products, e. g. , these genes and proteins, including probes, antisense constructs, and antibodies.

US Patent:

7133566, Nov 7, 2006

Filed:

Dec 20, 2001

Appl. No.:

10/029135

Inventors:

Adityo Prakash - Redwood Shores CA, US
David Kita - Foster City CA, US
Edward Ratner - Sunnyvale CA, US
Oliver Shih - San Jose CA, US
Hitoshi Watanabe - San Jose CA, US

Assignee:

Altera Corporation - San Jose CA

International Classification:

G06K 9/36

US Classification:

382243

Abstract:

A method of reconstructing a previously occluded area of a video image frame exposed by the motion of a segment within said image frame. In one embodiment the method involves approximating the color values of the pixels in the newly exposed area from the color values of the neighboring image segments. The process is refined by identifying a set of neighboring segments to the exposed area, called fill segments, that most closely resemble the color values of the pixels within the exposed area. These fill segments are then used to reconstruct the color values of the exposed area. In one embodiment, the identities of the fill segments are transmitted to an exemplary decoder.