David G Klein

US Patent:

6515745, Feb 4, 2003

Filed:

Oct 19, 2001

Appl. No.:

10/036062

Inventors:

Gerard H. Vurens - Palo Alto CA
David L. Klein - Palo Alto CA

Assignee:

HDI Instrumentation - Santa Clara CA

International Classification:

G01J 404

US Classification:

356369, 3562372, 356630, 250225

Abstract:

An optical measurement system for evaluating the surface of a substrate or the thickness and optical characteristics of a thin film layer overlying the substrate includes a light source for generating a light beam, a static polarizing element for polarizing the light beam emanating from the light source, and a measurement system for measuring the light reflected from the substrate location. The measurement system includes a static beam splitting element for splitting the light reflected from the substrate into s-polarized light and p-polarized light. The measurement system further includes two optical sensors for separately measuring the amplitude of the s-polarized light and the intensity of the p-polarized light. A control system analyzes the measured amplitude of the s-polarized light and the p-polarized to determine changes in the topography of substrate or changes in the thickness or optical characteristics of the thin film layer.

US Patent:

6678043, Jan 13, 2004

Filed:

Oct 31, 2000

Appl. No.:

09/703411

Inventors:

Gerard H. Vurens - Palo Alto CA 94303
David L. Klein - Palo Alto CA 94301

International Classification:

G01N 2188

US Classification:

3562372, 356369, 382145

Abstract:

There is described method and apparatus to create multi-dimensional non-spatial histograms of surfaces and to compare such histograms to show whether the surfaces substantially conform to one another. This analysis is particularly applicable to comparing die on wafers to determine whether manufactured devices conform to a master or whether one die is like another.

US Patent:

7374725, May 20, 2008

Filed:

Feb 11, 2004

Appl. No.:

10/777581

Inventors:

David L. Klein - Palo Alto CA, US
Stephen G. Boyer - Stockton CA, US
Gregory Andronaco - Palo Alto CA, US

Assignee:

Gener8, Inc. - Mountain View CA

International Classification:

B01L 3/00

US Classification:

422102

Abstract:

A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e. g. , oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.

US Patent:

7713486, May 11, 2010

Filed:

Feb 1, 2008

Appl. No.:

12/024973

Inventors:

David L. Klein - Palo Alto CA, US
Stephen G. Boyer - Stockton CA, US
Gregory Andronaco - Palo Alto CA, US

Assignee:

Microreactor Technologies, Inc. - Mountain View CA

International Classification:

B01L 3/00

US Classification:

422102

Abstract:

A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e. g. , oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.

US Patent:

7718134, May 18, 2010

Filed:

Feb 5, 2008

Appl. No.:

12/026450

Inventors:

David L. Klein - Palo Alto CA, US
Stephen G. Boyer - Stockton CA, US
Gregory Andronaco - Palo Alto CA, US

Assignee:

Microreactor Technologies, Inc. - Mountain View CA

International Classification:

B01L 3/00

US Classification:

422102

Abstract:

A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e. g. , oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.

US Patent:

7849459, Dec 7, 2010

Filed:

Nov 4, 2004

Appl. No.:

10/981255

Inventors:

Michael John Burkhart - Round Rock TX, US
David Klein - Georgetown TX, US
Brian Thomas Lillie - Cedar Park TX, US
Daniel Mark Schumacher - Pflugerville TX, US
Thomas J. Watson - Pflugerville TX, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 9/445
G06F 9/44

US Classification:

717174, 717168, 717120, 717108, 717116

Abstract:

Methods, systems, and products are provided for deploying Java applications in resource constrained environments. Embodiments include identifying a resource constraint of a target system and filtering the Java application in dependence upon the identified resource constraint. In many embodiments, identifying a resource constraint of a target system includes identifying limited runtime processing capabilities of the target system and filtering the Java application in dependence upon the identified resource constraint includes preprocessing a tag library of the Java application. In some embodiments, preprocessing a tag library is carried out by identifying a tag library descriptor of the Java application and copying a listener from the tag library descriptor to a deployment descriptor for the Java application.

US Patent:

7851204, Dec 14, 2010

Filed:

Jun 9, 2006

Appl. No.:

11/450855

Inventors:

David L. Klein - Palo Alto CA, US
Robert D. Laidlaw - Albany CA, US
Gregory Andronaco - Palo Alto CA, US
Stephen G. Boyer - Moss Beach CA, US

Assignee:

Pall Microreactor Technologies, Inc. - Mountain View CA

International Classification:

C12M 1/34
C12M 3/00

US Classification:

4352872, 4353053

Abstract:

A closure for a microreactor includes a cap that is configured to be inserted into a well of the microreactor. The cap, or at least a portion of the cap, is compliant so as to form a seal with the well when the cap is inserted. The cap includes an aperture that provides an airway between the inside of the well to the external environment when the cap is inserted into the well. A porous plug is inserted in the aperture, e. g. , either directly or in tube that extends through the aperture. The porous plug permits gas within the well to pass through the aperture while preventing liquids from passing through to reduce evaporation and preventing microbes from passing through to provide a sterile environment. A one-way valve may also be used to help control the environment in the well.

US Patent:

7887766, Feb 15, 2011

Filed:

Mar 29, 2010

Appl. No.:

12/749374

Inventors:

David L. Klein - Palo Alto CA, US
Stephen G. Boyer - Stockton CA, US
Gregory Andronaco - Palo Alto CA, US

Assignee:

Pall Microreactor Technologies, Inc. - Mountain View CA

International Classification:

B01L 3/00

US Classification:

422407

Abstract:

A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e. g. , oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.

Address:

212 Montell Dr, Georgetown, TX 78628

VIN:

1GYFK63897R351305

Make:

CADILLAC

Model:

ESCALADE

Year:

2007