David Galen Linde

US Patent:

20100280335, Nov 4, 2010

Filed:

Jan 26, 2010

Appl. No.:

12/694044

Inventors:

David L. Carlson - Fridley MN, US
Timothy J. Denison - Minneapolis MN, US
Ali H. Shoeb - Winchester MA, US
David E. Linde - Corcoran MN, US

Assignee:

Medtronic, Inc. - Minneapolis MN

International Classification:

A61B 5/00
A61B 5/11

US Classification:

600301, 600595

Abstract:

A patient state is detected with at least one classification boundary generated by a supervised machine learning technique, such as a support vector machine. In some examples, the patient state detection is used to at least one of control the delivery of therapy to a patient, to generate a patient notification, to initiate data recording, or to evaluate a patient condition. In addition, an evaluation metric can be determined based on a feature vector, which is determined based on characteristics of a patient parameter signal, and the classification boundary. Example evaluation metrics can be based on a distance between at least one feature vector and the classification boundary and/or a trajectory of a plurality of feature vectors relative to the classification boundary over time.

US Patent:

20100280579, Nov 4, 2010

Filed:

Jan 26, 2010

Appl. No.:

12/694053

Inventors:

Timothy J. Denison - Minneapolis MN, US
David L. Carlson - Fridley MN, US
Ali H. Shoeb - Winchester MA, US
David E. Linde - Corcoran MN, US

Assignee:

Medtronic, Inc. - Minneapolis MN

International Classification:

A61N 1/36

US Classification:

607 62

Abstract:

A patient state is detected with at least one classification boundary generated by a supervised machine learning technique, such as a support vector machine. The patient state can be, for example, a patient posture state. In some examples, the patient state detection is used to at least one of control the delivery of therapy to a patient, to generate a patient notification, to initiate data recording, or to evaluate a patient condition. In addition, an evaluation metric can be determined based on a feature vector, which is determined based on characteristics of a patient parameter signal, and the classification boundary. Example evaluation metrics can be based on a distance between at least one feature vector and the classification boundary and/or a trajectory of a plurality of feature vectors relative to the classification boundary over time.

US Patent:

20130053722, Feb 28, 2013

Filed:

Aug 20, 2012

Appl. No.:

13/589270

Inventors:

David L. Carlson - Fridley MN, US
Pedram Afshar - Minneapolis MN, US
Timothy J. Denison - Minneapolis MN, US
Jonathon E. Giftakis - Maple Grove MN, US
David E. Linde - Corcoran MN, US
Scott R. Stanslaski - Shoreview MN, US

Assignee:

Medtronic, Inc. - Minneapolis MN

International Classification:

A61B 5/05
A61N 1/36

US Classification:

600554, 607 45

Abstract:

Various embodiments concern identifying a biomarker in the presence of electrical stimulation. Various embodiments concern delivering electrical stimulation to a patient and sensing one or more signals while the electrical stimulation is being delivered, the one or more signals including data indicative of physiological activity. Various embodiments further include determining an intensity of the electrical stimulation and determining whether the data indicates the presence of a biomarker based on a variable threshold, the variable threshold being variable based on the intensity of the electrical stimulation. Various embodiments concern determining a relationship between stimulation intensity and a biomarker parameter to determine the variability of the variable threshold.

US Patent:

46274456, Dec 9, 1986

Filed:

Apr 8, 1985

Appl. No.:

6/720906

Inventors:

Fernando S. Garcia - Eden Prairie MN
Hartmut Ginnow-Merkert - Eden Prairie MN
Paul J. Anderson - Eden Prairie MN
David E. Linde - Eden Prairie MN
Bertram J. Hudson - Eden Prairie MN

Assignee:

Garid, Inc. - Eden Prairie MN

International Classification:

A61B 514

US Classification:

128770

Abstract:

Hand-held shirt-pocket portable medical diagnostic system for checking measurement of blood glucose, urea nitrogen, hemoglobin, blood components or other body qualities. The system includes the engagement of a disposable needle or lance probe package which carries a chemical reagent strip such as blood reacting chemistry. The system includes a pen structure having a visual readout, a microcomputer, and photosensing circuitry which measures the change of color of the blood reacting chemistry of the disposable probe package. The pen also includes a spring arrangement for actuating a needle or lance into the skin for transferring blood from a finger or other area to the chemical reagent strip. A disposable probe structure package includes configurations for transferring of the blood to the reagent strip of the reagent strip to the blood. The pen can also create a vacuum about a time period that the needle is penetrating the skin.

US Patent:

52792943, Jan 18, 1994

Filed:

Mar 26, 1990

Appl. No.:

7/499085

Inventors:

Paul J. Anderson - Bloomington MN
Ross A. Jessen - Chaska MN
David R. Linde - Maple Grove MN
Richard E. Jones - Bloomington MN
Bert Walter - Mendota Heights MN
Paul E. Christenson - Apple Valley MN

Assignee:

Cascade Medical, Inc. - Eden Prairie MN

International Classification:

A61B 514

US Classification:

128633

Abstract:

Hand-held shirt-pocket portable instrument for quantitative measurement of glucose or analysis in biological fluids. The system accepts a disposable diagnostic reagent test device which has a reagent carrier and mode of identifying to the instrument the reagent lot characteristics. The instrument includes a housing structure having a visual LCD readout, a microprocessor, and photosensing circuitry which measures the change of color of the reagent carrier upon reaction in the reacting chemistry of the disposable test device. The housing also includes a spring arrangement for actuating a disposable lancet into the skin for generating blood. The disposable diagnostic reagent unit includes a configuration for transporting of the blood in the regent unit. The system includes verification and calibration sequences for the electronics, the chemistry of an unused disposable unit, the presence of a blood sample, and the ambient temperature. The system also provides for storing a plurality of analysis readings.

US Patent:

47873981, Nov 29, 1988

Filed:

Jul 25, 1986

Appl. No.:

6/889185

Inventors:

Fernando S. Garcia - Eden Prairie MN
Hartmut G. Merkert - Eden Prairie MN
Paul J. Anderson - Eden Prairie MN
David E. Linde - Eden Prairie MN
Bertram J. Hudson - Eden Prairie MN

Assignee:

Garid, Inc. - Eden Prairie MN

International Classification:

A61B 514

US Classification:

128770

Abstract:

Hand-held shirt-pocket portable glucose medical monitoring system for checking measurement of blood glucose or other body qualities. The system includes a disposable diagnostic reagent-lancet unit which carries a chemcial reagent strip of blood reacting chemistry. The system includes a housing structure having a visual LCD readout, a microprocessor, and photosensing circuitry which measures the change of color of the blood reacting chemistry of the disposable unit. The housing also includes a spring arrangement for actuating a lancet into the skin for sampling and transporting blood from a finger to a chemical reagent. The disposable unit includes medical and fluid configurations for transporting of the blood to the reagent strip. The system inlcudes verification and calibration sequences for the electronics, the chemistry of an unused disposable unit, the presence of a blood sample, and multiple readings to an average result. The system also provides for storing a plurality of readings.

US Patent:

20220266031, Aug 25, 2022

Filed:

Feb 16, 2022

Appl. No.:

17/651374

Inventors:

- Minneapolis MN, US
David E. Linde - Corcoran MN, US
Scott R. Stanslaski - Shoreview MN, US
Christopher L. Pulliam - Plymouth MN, US
Rene A. Molina - Maple Grove MN, US
Abbey Beuning Holt Becker - Shoreview MN, US
David L. Carlson - Fridley MN, US
Nicholas D. Buse - New Brighton MN, US
Duane L. Bourget - Andover MN, US
Thaddeus S. Brink - St. Paul MN, US

International Classification:

A61N 1/36
A61N 1/05
A61N 1/372

Abstract:

An example method includes determining, by an implantable medical device (IMD), an electrode of a plurality of electrodes of a lead to be used to deliver electrical stimulation to a patient at a particular time; selecting, by the IMD and based on the determined electrode, a set of electrodes of the plurality of electrodes; and sensing, by the IMD and via the selected set of electrodes, electrical signals of the patient at the particular time.

US Patent:

20230069981, Mar 9, 2023

Filed:

Aug 8, 2022

Appl. No.:

17/818246

Inventors:

- Minneapolis MN, US
Scott R. Stanslaski - Shoreview MN, US
Abbey Beuning Holt Becker - Shoreview MN, US
Rene A. Molina - Maple Grove MN, US
Caleb C. Zarns - Minneapolis MN, US
David E. Linde - Bremerton WA, US
Nicholas D. Buse - New Brighton MN, US
Thaddeus S. Brink - St. Paul MN, US

International Classification:

A61N 1/36

Abstract:

An example system includes stimulation generation circuitry configured to deliver electrical stimulation to a patient; sensing circuitry configured to sense one or more biomarker signals; and processing circuitry configured to: cause delivery of electrical stimulation with the patient in a first patient state; receive a first instance of a biomarker signal in presence of the electrical stimulation with the patient in the first patient state; cause delivery of electrical stimulation with the patient in a second patient state; receive a second instance of the biomarker signal in presence of the electrical stimulation with the patient in the second patient state; determine whether a difference between the first instance of the biomarker signal and the second instance of the biomarker signal satisfies a threshold; select a therapy mode based on whether the difference satisfies the threshold; and cause delivery of electrical stimulation in accordance with the selected therapy mode.