3350 La Jolla Village Dr Suite 9-111F, San Diego, CA 92161 8585528585 (Phone), 8586426476 (Fax)
VA SAN DIEGO HEALTHCARE SYSTEM 3350 La Jolla Village Dr, San Diego, CA 92161 8585528585 (Phone), 8585527485 (Fax)
Certifications:
Infectious Disease, 1986 Internal Medicine, 1982
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School University of Missouri / Columbia Campus Graduated: 1979 Medical School Letterman Army Medical Center Graduated: 1979 Medical School Brooke Army Medical Center Graduated: 1979
University of Missouri, School of Medicine (Columbia) - Doctor of Medicine Brooke Army Medical Center - Fellowship - Infectious Disease (Internal Medicine) Letterman Army Medical Center - Residency - Internal Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine American Board of Internal Medicine Sub-certificate in Infectious Disease (Internal Medicine)
Name / Title
Company / Classification
Phones & Addresses
Mr David Looney Attorney
David A Looney, Co, LPA Attorneys & Lawyers
1735 South Main St.,, Akron, OH 44301 3304085186
David Looney Manager
Albertsons Grocery Stores
29941 Alicia Pkwy, Laguna Beach, CA 92677 Website: albertsons.com
David James Looney
David Looney MD Internist
3350 Ln Jolla Vlg Dr, San Diego, CA 92161 8585528585
Eric Poeschla - San Diego CA, US David Looney - Encinitas CA, US Flossie Wong-Staal - San Diego CA, US
International Classification:
C12N007/01
US Classification:
435/235100
Abstract:
The invention provides non-primate lentiviral vectors, packaging cells and packaging plasmids based, for example, on feline and ungulate retroviruses. In particular, the packaging plasmids are designed for expression in human cells (which are also used as packaging cells). The vectors of the invention transduce human cells, including difficult to target non-dividing cells of the hematopoietic and nervous system, in vitro and in vivo. The vectors are suitable for general gene transfer to these cells and for gene therapy to treat conditions mediated by these non-dividing cells including cancer and HIV infection.
Non-Primate Lentiviral Vectors And Packaging Systems
Eric Poeschla - San Diego CA, US David Looney - Encinitas CA, US Flossie Wong-Staal - San Diego CA, US
International Classification:
A61K048/00 C12N015/867 C12N007/00
US Classification:
424/093200, 514/044000, 435/456000, 435/235100
Abstract:
The invention provides non-primate lentiviral vectors, packaging cells and packaging plasmids based, for example, on feline and ungulate retroviruses. In particular, the packaging plasmids are designed for expression in human cells (which are also used as packaging cells). The vectors of the invention transduce human cells, including difficult to target non-dividing cells of the hematopoietic and nervous system, in vitro and in vivo. The vectors are suitable for general gene transfer to these cells and for gene therapy to treat conditions mediated by these non-dividing cells including cancer and HIV infection.
Compositions And Methods For Regulating Gene Transcription
Kevin V. Morris - San Diego CA, US David J. Looney - Encinitas CA, US Steven E. Jacobsen - Agoura Hills CA, US
International Classification:
A61K 31/7105 C12Q 1/68 C12Q 1/70 C12N 5/00
US Classification:
514 44 A, 435 6, 435 5, 435375
Abstract:
The invention is directed to compositions and methods for RNA-mediated gene regulation, e.g., transcription regulation, e.g., by transcriptional silencing of genes. In one aspect, the invention provides methods using siRNAs directed at a transcription regulator, e.g., a promoter or enhance sequence, of a gene target molecule. In one aspect, this results in in vivo DNA methylation and/or modification of associated chromatin (e.g., histone proteins) accompanied by and/or partial or complete transcription gene silencing in a cell, such as a mammalian cell, e.g., a human cell.
News
Study: Gene Therapy for HIV Safe, But Effectiveness Still Unclear
Dr. David Looney, director of the Center for AIDS Research at the University of California, San Diego, said the research is still "exciting and promising" since it shows that modified immune cells can last a long time, potentially decades.
Church at Charleston Park - Pastor (2013) Destiny Worship Center - Crestview Campus Pastor (2011-2013) Northwood Church at Carnes - Music Minister (2002-2011)
Education:
Liberty University - Theology, Lee University - Communications