David A Mcdaniel

US Patent:

6398753, Jun 4, 2002

Filed:

Oct 9, 1998

Appl. No.:

09/168683

Inventors:

David H. McDaniel - Virginia Beach VA 23454

International Classification:

A61B 1720

US Classification:

604 22

Abstract:

A system for enhancing and improving the transcutaneous or transdermal delivery of topical chemicals or drugs. A disposable container contains a substantially sterile unit dose of an active agent adapted for a single use in a medical treatment. The unit dose is formulated to enhance transport of the active agent through mammalian skin when the active agent is applied to the skin and the skin is exposed to light and/or ultrasound defined by at least one specific parameter.

US Patent:

6629971, Oct 7, 2003

Filed:

Feb 15, 2001

Appl. No.:

09/819081

Inventors:

David McDaniel - Virginia Beach VA 23452

International Classification:

A61B 1818

US Classification:

606 9, 606 32, 606127, 606131, 607 88, 607 98, 607101, 128898

Abstract:

A method for producing preferential damage to hair exiting mammalian skin. A agent having an average diameter for enabling the agent to penetrate the hair duct is selected. The agent is designed to attach to, or become physically incorporated into, the hair shaft, the hair follicle, the hair bulb or the hair duct. The agent has an electromagnetic radiation absorption characteristic which enables the agent to absorb a first wavelength of electromagnetic radiation from a skin-penetrating electromagnetic radiation source, such as a laser. The agent is applied to the skin so that the agent penetrates the skin and attaches to or becomes physically incorporated into the hair shaft, the hair follicle, the hair bulb or the hair duct. The agent is exposed to the first wavelength of electromagnetic radiation and absorbs the first wavelength of electromagnetic radiation.

US Patent:

6632218, Oct 14, 2003

Filed:

Oct 21, 1999

Appl. No.:

09/425156

Inventors:

Horace W. Furumoto - Wellesley MA
George Cho - Hopkinton MA
David H. McDaniel - Virginia Beach VA
Eric Koschmann - Hudson NH
Antonio G. Rizzo - Nashua NH

Assignee:

Cynosure, Inc. - Chelmsford MA

International Classification:

A61B 1818

US Classification:

606 9, 606 3, 128898, 607 88, 607 89

Abstract:

A long pulse alexandrite laser hair removal system is disclosed using light pulses of greater than 1 msec and fluences between 10 and 50 J/cm. The use of an alexandrite laser allows good penetration while still achieving an acceptable combination of hemoglobin and melanin absorption. The use an index-matching application on the skin sections to be treated is also described. This substance will be absorbed into the epidermal layer to provide better coupling of the laser light into the skin. Also, and most advantageously, it will reduce reflections at the epidermal-dermal junction, which can lead to the damage of the skin. Also a topical thermal or photochromic indicator is suggested since skin irradiation in the near-infrared generally does not produce any characteristic skin color change as is found when using pulsed dye lasers, for example.

US Patent:

6663659, Dec 16, 2003

Filed:

Jun 29, 2001

Appl. No.:

09/894899

Inventors:

David H. McDaniel - Virginia Beach VA 23452

International Classification:

A61N 5006

US Classification:

607 88, 607 90, 607 91, 606 3, 606 9, 128898

Abstract:

The invention is a system and method for the photomodulation of living tissue. When photomodulated, living tissue will exhibit bioactivation or bioinhibition according to the present invention and, when using the disclosed sources of narrowband multichromatic radiation can cause significant dermatologic advantages such as hair removal, hair growth stimulation, wrinkle reduction, acne reduction and scar removal, vitiligo, etc. This invention may be applied to non-dermatological medical treatments including tumor growth inhibition, cell regeneration, the stimulation of tissue in organs, etc.

US Patent:

6676655, Jan 13, 2004

Filed:

Apr 11, 2002

Appl. No.:

10/119772

Inventors:

David H. McDaniel - Virginia Beach VA

Assignee:

Light BioScience L.L.C. - Virginia Beach VA

International Classification:

A61B 1818

US Classification:

606 9, 606 3, 606 8, 607 88, 607 90, 607 91

Abstract:

Disclosed is a method for treating various dermatalogical conditions using electromagnetic radiation. Particularly preferred are narrowband, multichromatic electromagnetic radiation emitters having a dominant emissive wavelength corresponding to the peak absorption wavelength of the mammalian tissue targetted for treatment. Topical compositions are disclosed for pretreating the targetted tissue to alter the peak absorption wavelength of the tissue.

US Patent:

6887260, May 3, 2005

Filed:

Aug 22, 2001

Appl. No.:

09/933870

Inventors:

David H. McDaniel - Virginia Beach VA, US

Assignee:

Light BioScience, LLC - Virginia Beach VA

International Classification:

A61N005/006

US Classification:

607 88, 607 89, 607 91, 606 3, 606 9, 606 10

Abstract:

Disclosed is a system and method for treatment of skin disorders. More particularly, the disclosed invention is directed toward the treatment of acne and acne scarring by treating sebaceous oil glands and the surrounding tissue with an exogenous chromophore composition and then exposing the target tissue to visible, infrared, or ultraviolet light to inhibit the activity of the oil gland and eliminate acne bacteria. The treatment method of the present invention may be futher augmented by enhancing the penetration of the topical composition into the oil gland and surrounding tissue through the use of procedures including enzyme peeling, microderm abrasion, or ultrasound.

US Patent:

6936044, Aug 30, 2005

Filed:

Nov 8, 2001

Appl. No.:

09/986367

Inventors:

David H. McDaniel - Virginia Beach VA, US

Assignee:

Light BioScience, LLC - Virginia Beach VA

International Classification:

A61B018/18

US Classification:

606 9, 606 10, 607 88, 128898

Abstract:

A method and apparatus for producing hair growth stimulation using light energy, topical compositions, and combinations thereof. By using photomodulation resulting from cellular responses to exposure to specific wavelengths of light, optionally in conjunction with topical compositions and procedures for enhancing the penetration of such compositions, hair follicles are activated to produce hair growth.

US Patent:

7004933, Feb 28, 2006

Filed:

Jun 8, 2001

Appl. No.:

09/876157

Inventors:

David H. McDaniel - Virginia Beach VA, US

Assignee:

Light BioScience L.L.C. - Virginia Beach VA

International Classification:

A61M 31/00

US Classification:

604506, 604 22, 604500

Abstract:

A system for enhancing and improving the transcutaneous or transdermal delivery of topical chemicals or drugs. A disposable container contains a substantially sterile unit dose of an active agent adapted for a single use in a medical treatment. The unit dose is formulated to enhance transport of the active agent through mammalian skin when the active agent is applied to the skin and the skin is exposed to light and/or ultrasound defined by at least one specific parameter.