David R Piotrowski

US Patent:

20160058768, Mar 3, 2016

Filed:

Nov 12, 2015

Appl. No.:

14/939264

Inventors:

- New York NY, US
Robert Dullea - Groton MA, US
Julie Jia Li Hawkins - Weston CT, US
Allyn T. Londregan - Barrington RI, US
Paula M. Loria - Killingworth CT, US
Bruce Maguire - Chester CT, US
Kim F. McClure - Mystic CT, US
Donna N. Petersen - Salem CT, US
David W. Piotrowski - Waterford CT, US

International Classification:

A61K 31/519
A61K 31/4725
A61K 31/4545

Abstract:

The present invention is directed at substituted amide compounds, pharmaceutical compositions containing such compounds and the use of such compounds to reduce plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans.

US Patent:

20140315928, Oct 23, 2014

Filed:

Apr 15, 2014

Appl. No.:

14/253084

Inventors:

- New York NY, US
Robert Dullea - Groton MA, US
Julie Jia Li Hawkins - Weston CT, US
Allyn T. Londregan - Barrington RI, US
Paula M. Loria - Killingworth CT, US
Bruce Maguire - Chester CT, US
Kim F. McClure - Mystic CT, US
Donna N. Petersen - Salem CT, US
David W. Piotrowski - Waterford CT, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D 401/14
A61K 31/519
A61K 45/06
C07D 413/14
A61K 31/437
A61K 31/4709
A61K 31/4545
C07D 487/04
C07D 471/04

US Classification:

5142593, 544281, 546117, 514300, 546143, 514310, 546194, 514318, 546113

Abstract:

The present invention is directed at substituted amide compounds, pharmaceutical compositions containing such compounds and the use of such compounds to reduce plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans.