David F Power

US Patent:

6492361, Dec 10, 2002

Filed:

Oct 5, 2000

Appl. No.:

09/680810

Inventors:

Christopher A. Muller - Foothill Ranch CA
Elizabeth A. Bancroft - Irvine CA
Janet K. Cheetham - Laguna Niguel CA
Harold G. Jensen - Lake Forest CA
Teresa H. Kuan - Placentia CA
David F. Power - Trabuco Canyon CA
Kevin D. Skule - Rancho Santa Margarita CA

Assignee:

Allergan Sales, Inc - Irvine CA

International Classification:

A62K 3902

US Classification:

5142355, 514250, 514254, 514912

Abstract:

Compositions including a quinolone component in an amount effective as an antibiotic when the composition is placed in a mammalian eye, and a carrier component in an amount effective to act as a carrier for the quinolone component are provided. The present compositions are substantially free of other components effective as preservatives. Preferably the quinolone component has fungistatic activity. In one very useful embodiment, the compositions include a NSAID component in an amount effective to reduce inflammation or pain when the composition is placed in a mammalian eye. Methods of using the present compositions, for example, to resolve microbial infections and/or to reduce inflammation and/or pain in a mammalian eye are included within the scope of the present invention.

US Patent:

6548497, Apr 15, 2003

Filed:

Apr 19, 2001

Appl. No.:

09/838772

Inventors:

Janet K. Cheetham - Laguna Niguel CA
Harold G. Jensen - Lake Forest CA
Christopher A. Muller - Foothill Ranch CA
David F. Power - Trabuco Canyon CA
Kevin D. Skule - Rancho Santa Margarita CA

Assignee:

Allergan Sales, Inc. - Irvine CA

International Classification:

A61K 31535

US Classification:

5142355, 514912

Abstract:

Methods for reducing non-inflammatory pain caused by injuries and traumas include administering to a mammal eye having non-inflammatory pain a therapeutically effective amount of a composition comprising a quinolone component in an amount effective as an antibiotic and a NSAID component in an amount effective, in combination with the quinolone component, to provide a reduction in non-inflammatory pain.

US Patent:

6552020, Apr 22, 2003

Filed:

Jul 24, 2000

Appl. No.:

09/624129

Inventors:

Christopher A. Muller - Foothill Ranch CA
Elizabeth A. Bancroft - Irvine CA
Janet K. Cheetham - Laguna Niguel CA
Harold G. Jensen - Lake Forest CA
Teresa H. Kuan - Placentia CA
David F. Power - Trabuco Canyon CA
Kevin D. Skule - Rancho Santa Margarita CA

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 31535

US Classification:

5142355, 514250, 514912

Abstract:

Compositions including a quinolone component, such as ofloxacin, having fungistatic activity in the compositions, present in an amount effective as an antibiotic when the composition is placed in a mammalian eye, a NSAID component present in an amount to reduce inflammation or pain when the composition is placed in the eye, and a carrier component in an amount effective to act as a carrier for the quinolone component and NSAID component are provided. Methods of using the present compositions, for example, to resolve microbial infections and/or to reduce inflammation and/or pain in a mammalian eye are included within the scope of the present invention. Methods for treating corneal injuries are also included. In addition, methods for treating ocular infections, for example, corneal infections, are included.

US Patent:

7135455, Nov 14, 2006

Filed:

Nov 15, 2004

Appl. No.:

10/990054

Inventors:

Michael E. Stern - Mission Viejo CA, US
David Power - Trabuco Canyon CA, US

Assignee:

Allergan, Inc - Irvine CA

International Classification:

A61K 38/12

US Classification:

514 11

Abstract:

Methods of treating humans or animals having various conditions are disclosed which include administering a cyclosporine component. Among the conditions treated are dry mouth syndrome, verruciform xanthoma, achlorhydria, mucous cysts, oral submucous fibrosis, oral nevi, cancer of the oral mucosa, maloplakia of the genito-urinary tract, vulvovaginitis, helicobacter plylori infection, duodenal ulcers, peptic ulcers, conditions affecting the uterus and appendicitis.

US Patent:

7151085, Dec 19, 2006

Filed:

Nov 15, 2004

Appl. No.:

10/990055

Inventors:

Michael E. Stern - Mission Viejo CA, US
David Power - Trabuco Canyon CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 38/12

US Classification:

514 11

Abstract:

Methods of treating humans or animals having various conditions are disclosed which include administering a cyclosporinee component. Among the conditions treated are dry mouth syndrome, verruciform xanthoma, achlorhydria, mucous cysts, oral submucous fibrosis, oral nevi, cancer of the oral mucosa, maloplakia of the genito-urinary tract, vulvovaginitis, helicobacter plylori infection, duodenal ulcers, peptic ulcers, conditions affecting the uterus and appendicitis.

US Patent:

7368426, May 6, 2008

Filed:

May 5, 2006

Appl. No.:

11/429050

Inventors:

Michael E. Stern - Mission Viejo CA, US
David Power - Trabuco Canyon CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 38/13
A61K 38/12

US Classification:

514 11, 530321

Abstract:

Methods of treating humans or animals having rheumatoid arthritis are disclosed which include topically administering a therapeutically effective amount of a cyclosporine component to the human or animal, thereby treating the rheumatoid arthritis.

US Patent:

7902155, Mar 8, 2011

Filed:

Jun 30, 2006

Appl. No.:

11/479741

Inventors:

Michael E. Stern - Mission Viejo CA, US
David Power - Trabuco Canyon CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 38/13

US Classification:

514 205

Abstract:

Methods of treating humans or animals having dysfunctional oral mucosal tissue are disclosed which include topically administering cyclosporine A, salts thereof and/or mixtures thereof in an oral cavity of the human or animal.

US Patent:

8008338, Aug 30, 2011

Filed:

May 28, 2004

Appl. No.:

10/856192

Inventors:

Christopher A. Muller - Foothill Ranch CA, US
Janet K. Cheetham - Laguna Niguel CA, US
Teresa H. Kuan - Placentia CA, US
David F. Power - Trabuco Canyon CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 31/40

US Classification:

514413, 514912

Abstract:

Compositions comprising ketorolac tromethamine at a therapeutically effective concentration of less than 0. 5% are disclosed herein. Methods of treating or preventing ocular pain using said compositions are also disclosed herein.