David L Richman

US Patent:

59721901, Oct 26, 1999

Filed:

Nov 19, 1996

Appl. No.:

8/752669

Inventors:

David W. Richman - Huntington Beach CA

Assignee:

McDonnell Douglas Corporation - Huntington Beach CA

International Classification:

G01N 2726

US Classification:

204600

Abstract:

An electrophoresis chamber having the separation capability of a thicker chamber by the addition of a number of ports along the length of the chamber that can act as inlets or outlets. The device introduces cross flow by either a plurality of input and output ports along opposite walls of the chamber or by a tapered chamber having a plurality of output ports. Since the mobility of the particles is lateral to the direction of flow and the cross flow velocity is opposite in direction and greater than the maximum electrophoretic velocity of the particles being separated such particles are carried to the wall of a narrow linear chamber and will pass through ports provided in the wall spaced at strategic distances along the wall separation is achieved. In addition, because the sample and the outlet electrode surface are of like sign there is no deposition of the sample on the electrode surface.