David C Sek from 115 Chestnut St, Andover, MA 01810, age 45

Resumes

Owner And Head Coach

view source

Location:

400 Crossing Blvd, Bridgewater, NJ 08807

Industry:

Pharmaceuticals

Work:

Revel Racing
Owner and Head Coach
Formatech Oct 2002 - Mar 2004
Research Associate
Pfizer Oct 2002 - Mar 2004
Principal Scientist
Tanical Therapeutics Jun 2001 - Jul 2002
Chemist I

Education:

Northeastern University 2007 - 2010
Master of Science, Masters, Biology, Chemistry Bates College 1997 - 2001
Bachelors, Bachelor of Science, Chemistry

Skills:

Hplc
Protein Chemistry
Pharmaceutical Industry
Nmr
Differential Scanning Calorimetry
Biotechnology
Fluorescence
Lifesciences
Tlc
Molecular Biology
Endurance
Coaching
Triathlon
Running
Road Biking
Swimming

Interests:

Rock Climbing
Snowboarding
New Technologies
Triathlons

Research Scientist At Pfizer

view source

Position:

Research Scientist I at Pfizer

Location:

Greater Boston Area

Industry:

Biotechnology

Work:

Pfizer since Mar 2004
Research Scientist I
Formatech Oct 2002 - Mar 2004
Research Associate
Tanical Therapeutics Jun 2001 - Jul 2002
Chemist I

Education:

Northeastern University 2007 - 2010
M.S., Chemistry and Chemical Biology Bates College 1997 - 2001
B.S., Chemistry

Interests:

Snowboarding, rock climbing, triathlons, new technologies

Us Patents

Protein Formulations Containing Sorbitol
view source
US Patent:

20080200655, Aug 21, 2008
Filed:

Feb 15, 2008
Appl. No.:

12/032478
Inventors:

David C. Sek - North Andover MA, US
Assignee:

Wyeth - Madison NJ
International Classification:

C07K 17/02
US Classification:

5303905
Abstract:

The present invention provides a method for suppressing protein aggregation in a liquid formulation during freeze-thaw by including sorbitol in the liquid formulation. The present invention also provides methods for storing and preparing a liquid formulation containing a protein and sorbitol such that the presence of sorbitol suppresses protein aggregation during freezing and/or thawing.

Use Of Sucrose To Suppress Mannitol-Induced Protein Aggregation
view source
US Patent:

20080200656, Aug 21, 2008
Filed:

Feb 15, 2008
Appl. No.:

12/032490
Inventors:

David C. Sek - North Andover MA, US
Nicholas W. Warne - Andover MA, US
Kin Ho - Andover MA, US
Donna L. Luisi - North Andover MA, US
Angela Kantor - Pepperell MA, US
Assignee:

WYETH - Madison NJ
International Classification:

C07K 17/02
US Classification:

5303905
Abstract:

The present invention provides a method for suppressing mannitol-induced protein aggregation by providing sucrose to a liquid formulation containing a protein. The present invention also provides methods for storing and preparing a liquid formulation containing a protein and a combination of mannitol and sucrose such that the presence of sucrose suppresses mannitol-induced protein aggregation.

High Protein Concentration Formulations Containing Mannitol
view source
US Patent:

20080139792, Jun 12, 2008
Filed:

Dec 5, 2007
Appl. No.:

11/950986
Inventors:

David C. Sek - North Andover MA, US
Kin Ho - Andover MA, US
Assignee:

WYETH - Madison NJ
International Classification:

C07K 16/00
C07K 2/00
US Classification:

5303911, 530350, 530386
Abstract:

The present invention provides a method for inhibiting mannitol-induced aggregation of a protein in a liquid formulation by increasing the protein concentration to an amount greater than 50 mg/ml. The present invention also provides methods for storing and preparing a liquid formulation containing mannitol and a protein concentration greater than 50 mg/ml.