Deborah A Law

US Patent:

20030059852, Mar 27, 2003

Filed:

Mar 8, 2001

Appl. No.:

09/801089

Inventors:

David Phillips - San Mateo CA, US
Deborah Law - San Francisco CA, US
Lisa Alaimo - Los Altos CA, US

Assignee:

COR Therapeutics, Inc.

International Classification:

G01N033/53
A61K038/16
C07K014/00

US Classification:

435/007800, 514/007000, 530/350000

Abstract:

The present invention discloses that phosphorylation of cytoplasmic tyrosine residues in the -subunit of integrins is needed for signal protein association. The invention provides methods of identifying signaling partners involved in integrin mediated signaling, methods of identifying agents which block integrin mediated signaling, methods of using agents which block integrin mediated signaling to modulate biological and pathological processes, and agents which block integrin mediated signaling.

US Patent:

62109138, Apr 3, 2001

Filed:

Oct 18, 1996

Appl. No.:

8/734607

Inventors:

David R. Phillips - San Mateo CA
Deborah Ann Law - San Francisco CA
Lisa Nannizzi Alaimo - Los Altos CA

Assignee:

COR Therapeutics, Inc. - South San Francisco CA

International Classification:

G01N 3353
G01N 33567
G01N 33555
A61K 3800

US Classification:

435 78

Abstract:

The present invention discloses that phosphorylation of cytoplasmic tyrosine residues in the. beta. -subunit of integrins is needed for signal protein association. The invention provides methods of identifying signaling partners involved in integrin mediated signaling, methods of identifying agents which block integrin mediated signaling, methods of using agents which block integrin mediated signaling to modulate biological and pathological processes, and agents which block integrin mediated signaling.

US Patent:

20220332823, Oct 20, 2022

Filed:

Mar 31, 2022

Appl. No.:

17/709712

Inventors:

- Cambridge MA, US
Deborah LAW - Hillsborough CA, US
Amanda Elizabeth HANSON - Newton MA, US
Martin Yu FAN - Boston MA, US

International Classification:

C07K 16/28

Abstract:

The invention provides methods of treating cancer and methods for selecting treatment approaches for cancer.

US Patent:

20210380942, Dec 9, 2021

Filed:

Oct 24, 2019

Appl. No.:

17/288376

Inventors:

- Cambridge MA, US
Deborah LAW - Hillsborough CA, US
Amanda Elizabeth HANSON - Newton MA, US
Martin Yu FAN - Boston MA, US

International Classification:

C12N 5/0783
A61K 35/17

Abstract:

The invention provides compositions and methods for the treatment of cancer and infectious diseases.

US Patent:

20190367613, Dec 5, 2019

Filed:

May 14, 2019

Appl. No.:

16/411744

Inventors:

- Cambridge MA, US
Deborah LAW - Hillsborough CA, US
Amanda Elizabeth HANSON - Newton MA, US
Martin Yu FAN - Boston MA, US

International Classification:

C07K 16/28

Abstract:

The invention provides methods of treating cancer and methods for selecting treatment approaches for cancer.