Michael J. Welch - Creve Couer MO Deborah W. McCarthy - Maryland Heights MO Ruth E. Shefer - Newton MA Robert E. Klinkowstein - Winchester MA
Assignee:
Washington University - St. Louis MO
International Classification:
G21G 110
US Classification:
376195
Abstract:
Radionuclides are produced according to the present invention at commercially significant yields and at specific activities which are suitable for use in radiodiagnostic agents such as PET imaging agents and radiotherapeutic agents and/or compositions. In the method and system of the present invention, a solid target having an isotopically enriched target layer electroplated on an inert substrate is positioned in a specially designed target holder and irradiated with a charged-particle beam. The beam is preferably generated using an accelerator such as a biomedical cyclotron at energies ranging from about 5 MeV to about 25 MeV. The target is preferably directly irradiated, without an intervening attenuating foil, and with the charged particle beam impinging an area which substantially matches the target area. The irradiated target is remotely and automatically transferred from the target holder, preferably without transferring any target holder subassemblies, to a conveyance system which is preferably a pneumatic or hydraulic conveyance system, and then further transferred to an automated separation system. The system is effective for processing a single target or a plurality of targets.
Aurora Heights Public School Aurora Morocco 1962-1970, Norfolk House School Victoria Saudi Arabia 1969-1971, Aurora High School Aurora Morocco 1971-1975
Community:
Bill Insley, Cameron Hutchinson, Kevin Shillington, Jessica Elsdon