Deborah A. Paul - Gurnee IL Mark F. Knigge - Grayslake IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
C12Q 170 G01N 33576 C12N 1506 C07K 1610
US Classification:
435 5
Abstract:
Monoclonal antibodies are described which specifically bind to Hepatitis E Virus (HEV), and more particularly to HEV orf-2 antigen. Also provided are hybridoma cell lines which secrete these monoclonal antibodies, methods for using these monoclonal antibodies, and assay kits which contain these monoclonal antibodies.
The invention is a diagnostic immunoassay which detects human T-cell lymphotropic virus-III (HTLV-III) antigen. The immunoassay utilizes a sandwich assay technique and the addition of a labeled second antibody to increase sensitivity. The second antibody is from an animal species different from the first.
Mouse Monoclonal Antibodies To Hepatitis E Virus And Methods For Using Same
Deborah A. Paul - Gurnee IL Mark F. Knigge - Grayslake IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
C12Q 170 G01N 33576 C07K 1608 C12N 518
US Classification:
435 5
Abstract:
Monoclonal antibodies are described which specifically bind to Hepatitis E Virus (HEV), and more particularly to HEV orf-3 antigen. Also provided are hybridoma cell lines which secrete these monoclonal antibodies, methods for using these monoclonal antibodies, and assay kits which contain these monoclonal antibodies.