Debra L Allison

US Patent:

50682482, Nov 26, 1991

Filed:

Jun 22, 1989

Appl. No.:

7/369982

Inventors:

Allan N. Tischler - Oakland CA
Philippe L. Durette - New Providence NJ
Bruce E. Witzel - Westfield NJ
Kathleen M. Rupprecht - Cranford NJ
Timothy F. Gallagher - Harleysville PA
Marvin M. Goldenberg - Westfield NJ
Debra L. Allison - Basking Ridge NJ

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

A61K 3138

US Classification:

514443

Abstract:

Method for increasing resistance to gastro-intestinal irritation, and for the treatment of pain, fever, inflammation, arthritic conditions, asthma, allergic disorders, skin diseases, cardiovascular disorders, psoriasis, inflammatory bowel disease, glaucoma or other prostaglandin and/or leukotriene mediated diseases comprising the administration to a subject in need of such treatment, a non-toxic therapeutically effective amount of compound of formula I: ##STR1##.